|1.||Graves Disease (Basedow Disease)
|3.||Thyroid Neoplasms (Thyroid Cancer)
|1.||Rapoport, Basil: 28 articles (05/2015 - 03/2003)|
|2.||McLachlan, Sandra M: 27 articles (05/2015 - 03/2003)|
|3.||Laurberg, Peter: 25 articles (02/2016 - 10/2002)|
|4.||Nagayama, Yuji: 20 articles (10/2015 - 03/2002)|
|5.||Chen, Chun-Rong: 17 articles (05/2015 - 01/2004)|
|6.||Patanè, Salvatore: 14 articles (04/2012 - 05/2009)|
|7.||Marte, Filippo: 14 articles (04/2012 - 05/2009)|
|8.||Bartalena, Luigi: 13 articles (01/2015 - 10/2002)|
|9.||Davies, Terry F: 13 articles (06/2013 - 04/2006)|
|10.||Miyauchi, Akira: 12 articles (03/2015 - 04/2004)|
02/01/2006 - "Radioactive iodine provides a simple, effective, and safe treatment for cats with hyperthyroidism and is regarded by most authorities to be the treatment of choice. "
07/01/1999 - "In cases of iodine-related hyperthyroidism the concept of early and radical surgical treatment, following stabilization of the patient in a reasonably short amount of time shows best results and is thus favored. "
06/01/2008 - "The increase in remnant thyroid tissue radioactive iodine uptake was significantly greater in the patients operated upon for hyperthyroidism compared with those operated upon for nontoxic multinodular goitre (p = 0.0001). "
12/01/2007 - "Treatment with inorganic iodine for 7 months successfully relieved all symptoms of hyperthyroidism in both patients."
12/01/2003 - "Radioactive iodine was found to be a safe and an effective treatment for hyperthyroidism in Nigerian patients, but a high rate of default precludes adequate long-term follow-up."
|2.||Methimazole (Thiamazole)FDA LinkGeneric
09/01/2004 - "The objective of this study was to determine whether transdermal methimazole was as safe and effective as oral methimazole for the control of hyperthyroidism in cats. "
06/01/2014 - "Transdermal methimazole is a safe option for the long-term management of feline hyperthyroidism. "
04/01/2003 - "To determine whether once daily administration of methimazole was as effective and safe as twice daily administration in cats with hyperthyroidism. "
08/01/2001 - "This study evaluated the effect of methimazole pretreatment on the efficacy of 131I therapy in Graves' hyperthyroidism. "
05/01/1993 - "Study 1: GHRH (1 microgram/kg b.w.) was injected i.v. in 38 hyperthyroid patients and in 30 normal subjects; in 11 of the patients the GHRH test was repeated following methimazole-induced remission of hyperthyroidism. "
|3.||Antithyroid Agents (Antithyroid Drugs)IBA
03/01/1997 - "Effective treatment of fetal hyperthyroidism in pregnant women with high titers of thyroid stimulating autoantibody is possible by judicious administration of antithyroid drugs to the mother. "
02/20/1976 - "QKd is useful index not only for the rapid assessment of thyroid function as proposed by previous investigaters, but also for the rpaid evaluation of efficacy of antithyroid drugs administered in hyperthyroidism."
01/01/1995 - "All patients were treated with antithyroid drugs for at least 12 months; 29 patients had stable remission 24 or more months after withdrawal of treatment; 76 patients had persistent disease--66 unremitting/relapsing hyperthyroidism, 10 stable hypothyroidism--36 or more months after onset of disease. "
02/01/1983 - "If great care is taken to avoid overtreatment of the fetus, the treatment with antithyroid drugs is superior to surgical treatment, since surgery completely neglects the problem of fetal hyperthyroidism."
06/01/2013 - "TRAb can accurately predict short-term relapses of hyperthyroidism after a course of antithyroid drugs but are less effective in predicting long-term relapses or remissions. "
06/01/1985 - "[Importance of thyroid hormone determination in the diagnosis of hyperthyroidism--significant improvement in medical assessment using decision theory results]."
09/01/1985 - "Signs of hyperthyroidism may be subtle or misleading, particularly in the elderly; the well-informed clinician keeps the diagnosis in mind, and if the initial thyroid hormone tests are not definitive, employs additional tests that are cost-effective in the individual clinical situation."
10/01/1988 - "Although undetectable levels of TSH, compatible with hyperthyroidism, are occasionally noted in euthyroid patients with severe nonthyroidal illness and during the first trimester of pregnancy, false-positive results are less often recorded for TSH than for free or total thyroid hormone measurements. "
01/01/1985 - "The risk of recurrent hyperthyroidism can be eliminated indefinitely in patients with autonomously functioning thyroid tissue (AFTT) by selective surgery or radioiodine, whereas medical treatment inhibits only the actual thyroid hormone over-production. "
10/25/1975 - "[Letter: Severe hyperthyroidism cured by thyroid hormone therapy]."
|5.||Thyroxine (Levothyroxine)FDA LinkGeneric
02/01/2004 - "They have been used successfully to treat primary thyroidal hyperthyroidism and thyroxine overdose. "
06/01/1991 - "The administration of a dose of 131I selected by assessing the severity of the clinical signs, the size of the thyroid gland(s) and the serum level of thyroxine was an effective treatment for hyperthyroidism."
01/01/2012 - "Antioxidant and Protective Effects of Bupleurum falcatum on the L-Thyroxine-Induced Hyperthyroidism in Rats."
12/01/2003 - "The symptoms regressed in two of these patients without any specific treatment, one patient was treated with L thyroxin for hyperthyroidism without any improvement in the symptoms and one other patient had normal thyroid function. "
02/01/1998 - "The reduced bone mineral density associated with hyperthyroidism appears to be restored, maintained and in some cases possibly improved while on long-term thyroxine replacement post-radioiodine."
01/01/1986 - "The test of TSH-binding inhibiting antibodies is proving to be very useful for diagnosis and prognosis of hyperthyroidism. "
01/01/1997 - "In contrast to this transient, self-limited character of "autoimmune congenital hyperthyroidism", due to the clearance of maternal antibodies from the infant's circulation, some cases of persistent congenital hyperthyroidism without signs of thyroid autoimmunity have been recognized. "
10/31/1986 - "In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism. "
02/01/1986 - "We correctly predicted that C3 and an older sibling, C2, would have delayed onset of hyperthyroidism (approximately 45 days of age) due to interaction of these antibodies. "
01/01/2011 - "Studies in two small families of recombinant inbred strains showed that susceptibility to developing TSHR antibodies (measured by TSH binding inhibition, TBI) was linked to the MHC region whereas genes on different chromosomes contributed to hyperthyroidism. "
03/01/1980 - "Hyperthyroidism occurred at the age of 3 10/12 years and was treated successfully with propylthiouracil for 4 years. "
12/01/1984 - "Hyperthyroidism was effectively treated with propylthiouracil (PTU) with slightly increased basal TSH level and normal response of TSH to TRH. "
12/01/2006 - "[The effect of propylthiouracil on the efficacy of radioiodine (I-131) therapy in graves hyperthyroidism]."
10/01/1987 - "Remission in children with hyperthyroidism treated with propylthiouracil. "
04/01/2012 - "The aim of this study is to investigate the CIMT in patients with Graves' hyperthyroidism and the effect of propylthiouracil (PTU) therapy on CIMT. "
|8.||Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
04/01/1988 - "We report a prospective multicenter study, undertaken to compare the efficacy of 10 highly sensitive thyrotropin assay kits for the diagnosis of hyperthyroidism. "
08/01/1997 - "In the remission group, to exclude the influence of subclinical hyperthyroidism, thyrotropin (TSH) levels were followed and subjects with low levels excluded. "
08/01/1984 - "In contrast, there is now a large body of work which shows that thyrotrophin receptor antibody levels, central to the aetiology of Graves' hyperthyroidism, fall during antithyroid treatment and that remission may be related to this fall in a fashion which is dependent on the dose and duration of treatment. "
10/01/2006 - "A study population of 4087 subjects (2050 women) without overt hyperthyroidism or increased serum thyrotropin levels was available for the present study. "
09/01/2005 - "To evaluate the prevalence of latent and manifest hyperthyroidism in a non-selected group of patients admitted for contrast enhanced CT studies blood samples were tested for the levels of thyroid-stimulating hormone (TSH). "
07/01/2006 - "The results of this study indicate that twice daily administration of carbimazole ointment to the inner pinna of the ear is an effective treatment for hyperthyroidism in cats. "
01/01/2005 - "We conclude that carbimazole therapy is effective in treating nonautoimmune hyperthyroidism. "
01/01/1994 - "Carbimazole treatment was effective in controlling hyperthyroidism. "
06/01/2006 - "Carbimazole ameliorates hyperthyroidism but reduces radioiodine uptake and adversely affects the outcome of simultaneous radioiodine therapy. "
06/01/2012 - "We performed a prospective observational study in 20 adults (19 women) with acquired hyperthyroidism before and during carbimazole treatment. "
|10.||Thyrotropin Receptors (Thyrotropin Receptor)IBA
05/01/2014 - "The main difference in the clinical outcome of hyperthyroidism was that no patients with a TSH receptor mutation achieved euthyroidism throughout the follow-up, while 23.5% of patients without any mutation entered remission. "
02/01/2006 - "Adenovirus encoding the thyrotropin receptor A-subunit improves the efficacy of dendritic cell-induced Graves' hyperthyroidism in mice."
01/01/2006 - "Our previous studies using HEK-293 cells expressing the extracellular domain of the TSH receptor (TSHR) showed that Stat4-/- mice, which lack Th1 cells, are susceptible, whereas Stat6-/- mice, which lack Th2 cells, are resistant to the induction of Graves' hyperthyroidism. "
10/01/2015 - "All patients were further classified into three subgroups: a GD-active group (hyperthyroidism and TRAb (thyroid stimulating hormone receptor antibody) >7.5 U/L) (N=15), a GD-inactive group (euthyreosis and TRAb<1 U/L) (N=8), and other GD patients (euthyreosis and TRAb>1 U/L) (N=14). "
10/01/2015 - "The purpose of this article is to summarize the recent advances on experimental Graves' hyperthyroidism and orbitopathy as studied in two widely used mouse models, which involve repetitive genetic vaccinations using either adenovirus or in-vivo electroporation of the eukaryotic expression plasmid expressing the thyrotropin receptor (TSHR) as a vector. "
06/01/2002 - "In these patients, prompt treatment of their hyperthyroidism by total thyroidectomy may be the best option. "
07/01/1999 - "In most of the patients, immunologic remission was obtained by subtotal thyroidectomy except for their having recurrent hyperthyroidism. "
01/01/2011 - "This study evaluates quality of life in a standardized analogue fashion, with significant improvement reported in all quality of life measures and we conclude that thyroidectomy remains an excellent treatment option for patients with hyperthyroidism."
01/01/2009 - "Surgical thyroidectomy of patients with Graves' hyperthyroidism does not lead to immediate remission of the autoimmune abnormality, and the combination thyroidectomy+withdrawal of antithyroid medication+L-T(4) replacement of the mother involves a high risk of foetal hyperthyroidism. "
12/01/2006 - "Three (4%) patients who underwent subtotal thyroidectomy developed recurrent hyperthyroidism; all were treated successfully with radioiodine ablation. "
01/01/2015 - "After treatment of hyperthyroidism a significant decrease in free T3 (FT3) and free T4 (FT4) concentrations was accompanied by marked decrease of serum sclerostin (from 43.7 ± 29.3 to 28.1 ± 18.4 pmol/L; p < 0.001), OC (from 35.6 ± 22.0 to 27.0 ± 14.3 ng/mL; p < 0.001), and CTX (from 0.49 ± 0.35 to 0.35 ± 0.23 ng/dL; p < 0.005), accompanied by an increase of PTH (from 29.3 ± 14.9 to 39.8 ± 19.8; p < 0.001). "
02/01/1997 - "The purpose of this study was to determine whether the improvement in muscle performance after treatment of hyperthyroidism is only a result of an increased muscle mass or if it also depends on the improvement of intrinsic contractile function. "
05/01/2008 - "After treatment, all patients with cold nodules remained euthyroid: five patients with hot nodules normalized thyroid function, and the remaining sixteen showed a partial remission of hyperthyroidism. "
04/01/2007 - "Symptoms of CHF subsided and LVEF improved after treatment for hyperthyroidism. "
07/01/1992 - "Three months after treatment, a biochemical and clinical remission of hyperthyroidism was observed in 8 of 10 patients with toxic nodules. "
|3.||Drug Therapy (Chemotherapy)
01/01/2006 - "Graves' hyperthyroidism: how long should antithyroid drug therapy be continued to achieve remission?"
12/01/2000 - "The data here presented suggest that protocols I and II based on relatively low doses of radioiodine are rather effective in reducing Graves' hyperthyroidism in patients not submitted previously to antithyroid drug therapy. "
01/01/1985 - "Chemotherapy led to a remission of hyperthyroidism and tumoral syndrome for 4 months. "
02/01/1974 - "[Chemotherapy of hyperthyroidism and its remission in Japan]."
02/01/2001 - "The present study was designed to evaluate systolic cardiac function in patients with hyperthyroidism during a short-term and a long-term pharmacotherapy. "
02/01/1977 - "[Study of the space and time distribution of radiation dose as a basis for interpreting differences in the dose/effect relationship in external and metabolic radiotherapy of hyperthyroidism (author's transl)]."
04/01/2012 - "Permanent treatment of hyperthyroidism (by radioiodine or surgery) should be planned in patients with moderate-to-severe and active GO, followed by a course of ivGC associated with orbital radiotherapy, particularly when eye muscle involvement is present. "
01/01/2002 - "[Radiotherapy of hyperthyroidism--why, what for, when, how?]."
06/01/2001 - "While waiting for the remote effect of radiotherapy, the patient was given an antithyroid drug to control hyperthyroidism."
07/01/1999 - "We also review the literature on the three treatment options for hyperthyroidism in DS: surgery, medical treatment, and radiotherapy. "
|5.||Transplantation (Transplant Recipients)
01/01/2015 - "One patient was diagnosed with hyperthyroidism 2.5 years after transplantation. "
09/01/2007 - "Clinical hyperthyroidism appeared 7 months after transplantation, and a hypothyroid state was noted 2 months later. "
01/01/1998 - "Hyperthyroidism in a renal transplant recipient."
09/01/2007 - "These two illustrative cases, one of acquisition of hyperthyroidism and the other of remission of Sjgrens syndrome after transplantation, highlights that HSCT can induce adoptive autoimmune disease or cure coincidental autoimmune disease. "
09/01/2004 - "The occurrence of hyperthyroidism and/or Graves' disease (GD) in transplant recipients receiving immunosuppressive therapy is extremely rare. "