Renal Hypertension

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1033 relevant articles (24 outcomes, 83 trials/studies) found for this Disease

Description: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.

Also Known As:

Hypertension, Renal; Hypertensions, Renal; Renal Hypertensions

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Hypertension: 1033

Renovascular Hypertension: 2009

Female Urogenital Diseases and Pregnancy Complications

Female Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Hypertension: 1033

Renovascular Hypertension: 2009

Cardiovascular Diseases: 20552

Vascular Diseases: 7633

Hypertension: 76484

Renal Hypertension: 1033

Renovascular Hypertension: 2009

Related Diseases

1.	Hypertension (High Blood Pressure)
2.	Cardiomegaly (Heart Hypertrophy)
3.	Renal Artery Obstruction (Renal Artery Stenosis)
4.	Pheochromocytoma
5.	Heart Failure

Experts

1.	Prewitt, R L: 2 articles (09/2001 - 02/2000)
2.	Dobrian, A D: 2 articles (09/2001 - 02/2000)
3.	Heinig, Marcelo: 1 article (12/2006)
4.	Johnson, Richard J: 1 article (12/2006)
5.	Lobo, Peter I: 1 article (02/2006)
6.	Burtner, Christopher: 1 article (02/2006)
7.	Okusa, Mark D: 1 article (02/2006)
8.	Hu, Daniel C: 1 article (02/2006)
9.	Hong, Anna: 1 article (02/2006)
10.	Rizkalla, Bishoy: 1 article (04/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Renal Hypertension:

1.	Enalapril FDA LinkGeneric 01/01/1987 - "[Development of renal function in the transplanted patient with renal hypertension treated with enalapril]" 09/01/1989 - "Enalapril, the first nonsulfhydryl ACE inhibitor approved for general use in the United States, has demonstrated efficacy and safety in controlling blood pressure in patients with essential hypertension, renal parenchymal disease, renovascular hypertension, and diabetes with hypertension. " 09/01/1997 - "These included rodent models of renal hypertension in which candesartan cilexetil also demonstrated efficacy equivalent to or greater than enalapril. " 05/01/1997 - "METHODS: Two weeks after the surgery to produce chronic renal hypertension, half the hypertensive rats were treated orally with enalapril (30 mg/kg), an angiotensin-converting enzyme inhibitor, for 5 weeks. " 02/01/1992 - "We studied the effect of enalapril treatment on the contractile response to beta-adrenergic stimulation with isoproterenol in renal hypertension. " Order ALL the reference details at left...
2.	Captopril (Capoten)FDA LinkGeneric 01/22/1994 - "CONCLUSIONS: The post-captopril renogram may be a useful test in the functional study of renal behaviour in patients with vasculo-renal hypertension." 09/01/1996 - "The captopril test in children with renovascular and renal hypertension." 12/01/1991 - "[Effect of the ACE-inhibitor captopril on the blood pressure and kidney function of patients with essential and renal hypertension]" 04/19/1988 - "Captopril also delayed the onset of renal hypertension, with mean arterial pressure reaching hypertensive levels only 2 weeks after clipping. " 11/01/1987 - "The effect of captopril in renal hypertension in children." Order ALL the reference details at left...
3.	ReninIBA 08/01/1976 - "A comparison of the renin stimulation values of patients with renal hypertension also revealed a significant reduction (p less than 0.01). " 01/01/1984 - "This study demonstrates that unlike the AV3V region the SFO is not critical for the development of non-renin dependent renal hypertension." 10/01/1972 - "Prognostic value of simultaneous renal venous renin and split function studies in unilateral renal hypertension." 06/01/1997 - "Renin angiotension system may be involved in the cardiac hypertrophic and MHC gene switch during the development and maintenance of 2K1C renal hypertension." 01/01/1996 - "The significance of aortorenal and selective angiography of renal arteries with determination of peripheral blood plasma renin activity as well as of individual vein renalis and vein cava blood samples in diagnosing of renal hypertension. " Order ALL the reference details at left...
4.	SodiumIBA 11/01/2005 - "In models of genetic hypertension, renal tubular dysfunction could be involved in the increased sodium and water reabsorption. " 05/01/2003 - "In the pathogenesis of renal hypertension sodium retention is involved with volume expansion and an impaired ratio of the formation of vasoactive (vasopressor and vasodepressor) substances. " 06/29/1998 - "In the pathogenesis of renal hypertension an important role is played by sodium and fluid retention and activation of the renin-angiotensin system. " 07/01/1992 - "Sympathetic nervous system in high sodium one-kidney, figure-8 renal hypertension." 01/01/1992 - "At the prehypertensive stage of essential hypertension, renal dopaminergic activity was suppressed, which induced the retention of body fluids and sodium. " Order ALL the reference details at left...
5.	Angiotensin IIIBA 11/01/1966 - "[Studies on the metabolism of I-132 angiotensin II in experimental renal hypertension and its alteration by renal veno-portal anastomosis in dogs]" 11/01/2004 - "Sympathetic activity in patients with CRF can be normalized, and angiotensin II-independent sympathetic hyperactivity contributes to the pathogenesis of renal hypertension. " 03/01/1998 - "However, the arterial hypertension, renal vasoconstriction, and reduced PBF present in chronic NO-deficient hypertensive rats is partially due to the effects of angiotensin II, via stimulation of AT1-receptors." 09/01/1987 - "6. These results suggest that angiotensin II is not involved in the increased blood pressure variability of renal hypertension and that some other irreversible mechanism is responsible." 02/01/1980 - "These observations suggest a generalized vascular refractoriness to exogenous angiotensin II in the pregnant ewe with experimental renal hypertension." Order ALL the reference details at left...
6.	Hydralazine (Apresoline)FDA LinkGeneric 09/01/1958 - "Hypertensive vascular disease as a consequence of increased arterial pressure; quantitative study in rats with hydralazine-treated renal hypertension." 09/11/1981 - "- In a second series of eleven additional patients with treatment-resistant renal hypertension the blood-pressure lowering effect of hydralazine and minoxidil was compared in an open cross-over trial. " 10/01/1978 - "Modification of experimental renal hypertension in the rat by indomethacin and hydralazine." 12/01/1990 - "By using the two-kidney, one-clip (2K1C) rat model of renal hypertension with and without hydralazine treatment, CK (total and isoenzyme), lactate dehydrogenase, and citrate synthase activities and myocyte size were measured. " 01/01/1984 - "Captopril treatment was given to 30 children aged 8 months to 16 years (mean age 10.1 years) with renal hypertension when combinations of one or more of betablockers, diuretics, clonidine and hydralazine had failed to reduce blood pressure in the majority of the children. " Order ALL the reference details at left...
7.	Labetalol (Normodyne)FDA LinkGeneric 01/01/1984 - "Numerous studies have demonstrated that labetalol intravenously or orally gives a rapid fall of blood pressure in essential and renal hypertension. " 10/10/1980 - "The haemodynamic reaction to an acute emotional stress was tested in nine patients with essential and eleven with renal hypertension after an intravenous bolus of labetalol (0.6--1.6 mg/kg body-weight). " 01/01/1979 - "2 Monotherapy with labetalol was adequate in 12 out of 19 patients with essential hypertension and in 15 out of the 22 with renal hypertension. " 07/01/1983 - "Studies have shown that labetalol is effective in the treatment of essential hypertension, renal hypertension, pheochromocytoma, pregnancy hypertension and hypertensive emergencies. " 12/01/2002 - "The experimental acute renal hypertension is due to acute release of renin and generation of endogenous angiotensin II, and is specifically prevented by the angiotensin II type 1 receptor blocker, irbesartan, but not by labetalol." Order ALL the reference details at left...
8.	Ramipril (Altace)FDA LinkGeneric 11/01/2000 - "The study demonstrates that ramipril is an efficacious antihypertensive agent in children with renal hypertension. " 01/01/1990 - "Preliminary data indicate that ramipril may be effective in indications such as severe essential hypertension and renal hypertension. " 11/01/2000 - "Effect of ramipril on ambulatory blood pressure and albuminuria in renal hypertension." 08/06/2007 - "This review explores these data in areas, such as hypertension, renal disease, and cardiovascular disease, and draws on this preliminary evidence to support the rationale for the Ongoing Telmisartan Alone in Combination with Ramipril Global Endpoint Trial (ONTARGET) program, which aims to fully explore the clinical end points and effects of dual RAAS blockade in patients at high risk for cardiovascular outcomes." Order ALL the reference details at left...
9.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/20/2005 - "This association was similar regardless of hypertension, renal insufficiency, or treatment with ACE inhibitors (p for all interactions > 0.2). " 05/01/2004 - "BACKGROUND: Angiotensin-converting enzyme inhibitors are the drugs of choice in renal hypertension. " 01/01/1995 - "ACE inhibitors proved able to correct intrarenal hypertension: renal functional reserve returned to normal on posttreatment month 1-3 in 10 of 16 patients. " 07/01/1990 - "In conclusion it can be said that angiotensin converting enzyme inhibitors are efficient in the treatment of renal hypertension." 01/01/1987 - "These results may indicate that ACE plays an important role in the maintenance of chronic phase of 2-kidney, 1-clip renal hypertension and that suppression of vascular ACE activities might be a mechanism underlying the hypotensive effect of ACE inhibitors." Order ALL the reference details at left...
10.	Reserpine (Serpasil)FDA Link 05/01/1966 - "[The hypotensive effect of reserpine, furosemide and reserpine in combination with furosemide in experimental renal hypertension in rats]" 05/01/1958 - "Sodium restriction and reserpine administration in experimental renal hypertension; a correlation of arterial blood pressure responses with the ionic composition of the arterial wall." 09/01/1976 - "Tests conducted on anesthetized rats with experimental renal hypertension demonstrated that octadine, reserpine and methyl-DOPA with their one-time administration produce at the onset of the maximal hypotensine effect of fall of the arterial pressure at the expense of the lowered total peripheral resistance. " 01/01/1997 - "TRX was also as effective in decreasing urinary albumin excretion and preserving the renal function as ACEI or AIIRA in Group I. The improvement of albuminuria, glomerular enlargement and sclerosis after these treatments in Group II was significantly less than that in Group I. It appears that the early treatment with angiotensin converting enzyme inhibitor, angiotensin II receptor antagonist or reserpine, hydralazine and hydrochlorothiazide (TRX) may prevent glomerular injury in human patients with renal hypertension." 01/01/1984 - "Fifty-five patients suffering from essential or renal hypertension who had been insufficiently treated previously with combination therapy using diuretics and beta-blockers as well as reserpine, clonidine, prazosin, captopril, or minoxidil have been included in this open study. " Order ALL the reference details at left...

Therapies and Procedures

1.	Nephrectomy 02/01/2003 - "CONCLUSIONS: Partial nephrectomy provides an excellent nephron sparing cure for segmental renal hypertension. " 12/01/1985 - "A case of renal hypertension after pyelolithotomy cured by segmental nephrectomy is reported. " 12/01/1985 - "[A case of renal hypertension after pyelolithotomy cured by segmental nephrectomy]" 01/01/1965 - "RENAL HYPERTENSION SECONDARY TO UNILATERAL RADIATION DAMAGE RELIEVED BY NEPHRECTOMY." 01/01/1956 - "Unilateral renal hypertension in a girl cured by nephrectomy." Order ALL the reference details at left...
2.	Surgical Instruments (Clip) 01/01/2003 - "Doppler study revealed that 37.5% patients had orthostatic extravasal obstruction of the left renal vein in the aortomesenterial "forceps" (0.15 +/- 0.03 cm, p > 0.05) with a significant decrease in volumetric blood flow velocity by 44 +/- 30.01 ml/min. Postsurgical signs of venous renal hypertension were seen in 2 patients. " 10/01/1998 - "1. The objective of this study was to determine the influence of gender on the development of renal hypertension in Sprague-Dawley rats using the Goldblatt two-kidney, one-clip (2K1C) model. " 01/01/1997 - "To test this hypothesis, in this study we compared the vascular growth response of the spontaneously hypertensive rat (SHR) and Wistar-Kyoto rat (WKY) following induction of one kidney, one clip (1KlC) renal hypertension. " 10/01/1991 - "The present study has examined the time course of autonomic tone changes in two-kidney, one-clip (2K1C) and one-kidney, one-clip (1K1C) renal hypertension. " 04/01/1986 - "The purpose of this study was to assess whether two-kidney, one clip (2K1C) renal hypertension can be induced in the marmoset. " Order ALL the reference details at left...
3.	Ligation 11/01/2008 - "Effects on the rat ECG and renal hypertension (induced by left renal artery ligation) were also investigated. " 01/01/1990 - "Malignant renal hypertension was induced to Wistar rats by means of two methods (Lörincz-Gorácz and Rojo-Ortega-Genest procedures), and hypoxaemia was produced by application of two ligatures to an aortic segment, for two hours. " 08/01/1988 - "The response to 20-s carotid occlusion and the HR responses to electrical stimulation of the vagus nerve were normal in rats with renal hypertension, 12 days after aortic ligation. " 07/01/1987 - "Renal hypertension was induced by bilateral compression of both kidneys using figure-of-eight ligatures. " 01/01/1986 - "The initial phase of renal hypertension induced by ligature of the abdominal aorta was accompanied by a transient increase in vascular permeability. " Order ALL the reference details at left...
4.	Transplantation (Transplant Recipients) 01/01/2002 - "It improved the control of hypertension renal transplantation being the single most common cause of drop-out." 07/01/1991 - "The role of the kidney in the aetiology of hypertension: renal transplantation studies in rats." 11/30/1964 - "THE COURSE OF RENAL HYPERTENSION AFTER BILATERAL NEPHRECTOMY AND TRANSPLANTATION." 02/01/1994 - "The incidence of disturbed circadian rhythm was higher in the groups with renal hypertension (4/17 in the subgroup with normal renal function, 5/16 in the group with renal failure and/or transplantation). " 11/01/1976 - "Utilizing the microsurgical method of transplantation in the rat, the role of the kidney in an experimental renal hypertension due to segmental renal infarction was studied. " Order ALL the reference details at left...
5.	Angioplasty (Angioplasties) 07/01/1989 - "This study shows that percutaneous renal ablation is a useful and successful method of therapy for renal hypertension, and that it should be considered in patients unsuitable for surgery or angioplasty." 12/01/2007 - "Between 1986 and 2005, 22 patients (mean age, 14.7 years; range, 3-21) with renal hypertension underwent renal artery revascularization for 28 lesions, 23 with open repair (OR) and 5 with percutaneous transluminal renal angioplasty (PTRA). " 09/01/2009 - "Percutaneous transluminal renal angioplasty (PTRA) with stenting has been effective in the control of hypertension, renal function and pulmonary edema caused by atherosclerotic renal artery stenosis (ARAS). " Order ALL the reference details at left...

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