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Hyperphagia (Overeating)

Ingestion of a greater than optimal quantity of food.
Also Known As:
Overeating; Polyphagia; Polyphagias
Networked: 2974 relevant articles (107 outcomes, 236 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Obesity
2. Polydipsia
3. Body Weight (Weight, Body)
4. Polyuria
5. Hyperglycemia

Experts

1. Butler, Merlin G: 17 articles (01/2022 - 04/2005)
2. Bi, Sheng: 15 articles (01/2018 - 10/2005)
3. Farooqi, I Sadaf: 14 articles (01/2022 - 12/2006)
4. Moran, Timothy H: 14 articles (01/2021 - 03/2002)
5. Leibowitz, Sarah F: 14 articles (01/2016 - 05/2004)
6. Woods, Stephen C: 13 articles (09/2013 - 08/2002)
7. Schwartz, Michael W: 11 articles (12/2020 - 03/2002)
8. Olszewski, Pawel K: 10 articles (11/2022 - 04/2003)
9. Baldo, Brian A: 10 articles (06/2022 - 01/2004)
10. Miller, Jennifer L: 10 articles (01/2022 - 03/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperphagia:
1. Glucose (Dextrose)FDA LinkGeneric
2. LeptinIBA
3. Insulin (Novolin)FDA Link
4. CarbohydratesIBA
5. Streptozocin (Streptozotocin)FDA Link
6. Blood Glucose (Blood Sugar)IBA
7. MelanocortinsIBA
8. Growth Hormone (Somatotropin)IBA
9. FenfluramineIBA
10. LiraglutideFDA Link

Therapies and Procedures

1. Therapeutics
07/01/2021 - "Finding new therapies directed towards increasing TRHergic activity in NAc may be protective against overeating."
07/07/2023 - "Therapies that target hyperphagia may alleviate the extensive clinical and nonclinical impacts experienced by patients with BBS and their caregivers."
01/21/2023 - "The control of hyperphagia and improving food-related behaviors are the most important unmet needs in PWS and could be addressed with the development of a new therapeutic agent, as currently no approved therapeutics exist for PWS treatment. "
01/01/2022 - "Our analysis revealed seven main themes: (1) Experiencing a sense of uncertainty, as interviewees perceived treatment choices not to be based on medical evidence; (2) Establishing challenging relationships with the self and the other, as they did not feel understood and felt ashamed or hopeless about their condition; (3) Being stuck in one's own or the health professionals' beliefs about the disease management, as a common thought was the perception of movement as something dangerous together with a frequent prescription of passive therapies; (4) Dealing with one's own attitudes towards the disease; Understanding (5) the barriers to and (6) the facilitators of the adherence to therapeutic exercise, which revolve around the therapy cost, the time needed and the patients' willingness to change their life habits and (7) Developing an uneasy relationship with food since the diet was considered as something that "you force yourself to follow" and overeating as a way "to eat your feelings". "
01/01/2021 - "Therapies that target hyperphagia are in development, but understanding the value of these therapies to inform patient-focused drug development (PFDD) requires valid data on disease burden. "
2. Glycemic Control
3. Transcranial Direct Current Stimulation
4. Oral Administration
5. Aftercare (After-Treatment)