|3.||Primary Hyperoxaluria (Oxaluria, Primary)
|4.||Kidney Calculi (Kidney Stone)
|1.||Khan, Saeed R: 19 articles (05/2015 - 09/2002)|
|2.||Varalakshmi, Palaninathan: 11 articles (09/2008 - 08/2004)|
|3.||Hatch, Marguerite: 10 articles (04/2015 - 01/2003)|
|4.||Hoppe, Bernd: 10 articles (05/2014 - 10/2003)|
|5.||Lieske, John C: 9 articles (08/2012 - 09/2005)|
|6.||Kalaiselvi, Periandavan: 8 articles (07/2013 - 02/2002)|
|7.||Asplin, John R: 7 articles (02/2011 - 12/2002)|
|8.||Nakada, Stephen Y: 6 articles (11/2015 - 03/2009)|
|9.||Singla, S K: 6 articles (09/2015 - 01/2007)|
|10.||Goldfarb, David S: 6 articles (09/2014 - 01/2004)|
12/01/2013 - "This study confirms that meaningful reductions of urine oxalate and supersaturation of calcium oxalate can be achieved with dietary management of hyperoxaluria on a larger clinical scale. "
07/01/2005 - "Histopathological examination showed that there was no deposition of calcium oxalate crystals in rats in group 2. This is the first study to demonstrate in-vivo evidence that hyperoxaluria-induced peroxidative injury induces individual calcium oxalate crystal attachment in the renal tubules. "
09/01/2004 - "This study shows the power of MA as an exploratory technique, and changes in the expression of several physiologically important genes whose expression has not previously been reported to be affected by hyperoxaluria or calcium oxalate crystalluria."
03/01/2003 - "The aim of the present study was to clarify the role of dietary oxalate in urinary oxalate excretion and to assess dietary risk factors for hyperoxaluria in calcium oxalate stone patients. "
08/01/1995 - "Monolayer cultures of nontransformed monkey kidney epithelial cells (BSC-1 line) and calcium oxalate monohydrate (COM) crystals were used as a model system to study cell responses to crystal interactions that might occur in the nephrons of patients during periods of hyperoxaluria. "
06/01/1992 - "In the case of animals fed calcium along with oxalate, 35% of the oxalate was still present in the stomach, and the amounts of oxalate in the intestinal segments gradually increased from 4.5% to 21.7% (0-90 cm) and dropped to 2.1% in the next 20 cm. Since oxalaemia and oxaluria appear to be influenced by intestinal oxalate absorption, the present observations may help to improve understanding of the pathophysiology of disorders exhibiting altered oxalate metabolism."
01/01/2014 - "The low salt, normal calcium diet decreased urinary calcium (MD -45.00 mg/d, 95% CI -74.83 to -15.17) and oxalate excretion (MD -4.00 mg/d, 95% CI -6.44 to -1.56).A small study (17 participants) compared the effect of dietary fibre as part of a low calcium, low oxalate diet over three weeks, and found that although calciuria levels decreased, oxaluria increased. "
07/01/2007 - "This study sought to reduce urinary oxalate excretion in calcium stone formers with idiopathic hyperoxaluria. "
06/01/2002 - "The aim of the present study was to evaluate oxaluria in normocalciuric and hypercalciuric lithiasic patients under different calcium intake. "
01/01/1980 - "The study shows that renal oxalate excretion in patients with enteric hyperoxaluria can be reduced by oral calcium. "
|3.||Pyridoxine (Pyridoxin)FDA LinkGeneric
03/01/2005 - "Approximately half of PHI patients experience improvement in the degree of hyperoxaluria following pyridoxine (VB6) treatment. "
06/27/1981 - "Hyperoxaluria and recurrent stone formation apparently cured by short courses of pyridoxine."
05/01/2011 - "Dietary management and medical treatment using pyridoxine may be an effective first-line therapy to decrease hyperoxaluria in patients who form stones."
05/01/2011 - "Pyridoxine and dietary counseling for the management of idiopathic hyperoxaluria in stone-forming patients."
05/01/2009 - "A significant rise of the EGOT index ( > 1.5), oxaluria (from 74.8 +/- 5.2 to 117.9 +/- 12.3 mcM/l, p = 0.035), and crystalluria in rats fed with pyridoxine deficient diet were revealed. "
|4.||Ethylene Glycol (Monoethylene Glycol)IBA
06/01/2012 - "The present study aims at systematic evaluation of the calyces of Hibiscus sabdariffa to establish its scientific validity for anti-urolithiatic property using ethylene glycol-induced hyperoxaluria model in male albino rats. "
08/01/2015 - "In Group I severe hyperoxaluria was induced by ethylene glycol (EG) (0.75%) administration for 28 days. "
01/01/2015 - "Hyperoxaluria and renal injury were induced in healthy male Wistar rats by chronic exposure to ethylene glycol (EG, 0.75%) in the drinking water for 4 weeks. "
06/01/2013 - "16 male Spraque-Dowley rats were divided into two groups: Group 1 (n:8) received only distilled water; Group 2 (n:8) received 0.75 % ethylene glycol (EG) in their daily water to induce hyperoxaluria for 2 weeks. "
02/01/2012 - "Hyperoxaluria was induced by continuous administration of ethylene glycol (0.75%). "
|5.||Vitamin EFDA LinkGeneric
08/01/2006 - "Another group of EG-treated rats received 200 mg kg(-1) of vitamin E intraperitoneally (EG+E group) to evaluate its effect on hyperoxaluria. "
07/01/2005 - "One group (n = 100) was administered the antioxidant vitamin E at 400 mg/day given as an oral supplement along with standard therapeutic drugs for hypertension and hyperoxaluria and the patients were followed for a period of 9 months. "
07/01/2005 - "To determine whether vitamin E prevents hyperoxaluria-induced stone formation, using a new animal model of calcium oxalate stone disease, as our previous in- vitro and in-vivo studies showed that oxalate and hyperoxaluria induce free-radical generation, which results in peroxidative injury to renal tubular cells. "
07/01/2005 - "Vitamin E therapy prevents hyperoxaluria-induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant status."
06/01/2003 - "Supplementation of vitamin E and selenium prevents hyperoxaluria in experimental urolithic rats."
|6.||Hydroxyproline (4 Hydroxyproline)IBA
10/01/2011 - "Improved methodology to induce hyperoxaluria without treatment using hydroxyproline."
03/01/2010 - "In this study, we sought to create a model of hyperoxaluria in the adult sow by feeding hydroxyproline (HP). "
10/01/2011 - "The use of hydroxyproline (HP) to generate hyperoxaluria in the rat is a problem because it is impossible to separate the effect of oxalate on renal injury from the effects of HP and the large array of metabolic intermediates formed when HP is converted to oxalate. "
03/01/2010 - "Hydroxyproline-induced hyperoxaluria using acidified and traditional diets in the porcine model."
08/01/2009 - "Hyperoxaluria was induced by adding hydroxyproline (HP) to the drinking water. "
|7.||Allopurinol (Remid)FDA LinkGeneric
07/01/1990 - "Our results indicate that allopurinol does not have a specific effect on oxalate metabolism or oxaluria."
09/01/1989 - "Failure of allopurinol to modify urinary composition in enteric hyperoxaluria."
08/01/1987 - "Allopurinol may be the proper drug in the treatment of oxaluria and stone formation or of bilharzial patients."
08/01/1987 - "Biochemical studies on bilharzial and nonbilharzial hyperoxaluria: effect of pyridoxine and allopurinol treatment."
01/01/1981 - "Satisfactory therapies are given for uricosuria with allopurinol and for oxaluria with pyridoxine. "
|8.||Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA
01/01/2012 - "We discuss how the knowledge of the molecular parameters for alanine-glyoxylate aminotransferase required for peroxisomal translocation could become useful for improved hyperoxaluria type 1 treatment."
03/01/2011 - "Wild-type (WT) mice and mice deficient in liver alanine-glyoxylate aminotransferase (Agxt) exhibiting hyperoxalemia and hyperoxaluria were used in these studies. "
11/01/2001 - "Three novel deletions in the alanine:glyoxylate aminotransferase gene of three patients with type 1 hyperoxaluria."
06/01/1999 - "Molecular analysis of hyperoxaluria type 1 in Italian patients reveals eight new mutations in the alanine: glyoxylate aminotransferase gene."
06/01/1996 - "It is caused by deficient activity of hepatic peroxisomal alanine:glyoxylate aminotransferase (AGT), which results in hyperoxalemia and hyperoxaluria. "
|9.||Uric Acid (Urate)IBA
04/01/2013 - "There was no significant difference in 24-hour uric acid between the nongout and gout cohorts but hyperoxaluria was more common in patients with gout (74% vs 61%, p = 0.009). "
01/01/1995 - "Hypercalciuria was an inconsistent finding like in other reports; elevated uric acid excretion and hyperoxaluria were observed in 5 and 6 cases, respectively. "
07/01/2012 - "xanthocarpum decreases hyperoxaluria, calcium, and uric acid, improves renal function, and also produces antioxidant effects. "
06/01/1999 - "Higher oxaluria and calciuria as well as supersaturation of calcium oxalate and uric acid appear to be the most important factors. "
08/01/1988 - "Mean values of magnesium and uric acid were 0.04 +/- 0.02 and 0.30 +/- 0.08 mg/100 ml FG, respectively and the oxaluria was 34.51 +/- 16.35 mg/day/1.73 m2."
|10.||glycolic acid (glycolate)IBA
08/01/2011 - "The cristalluria study, oxaluria and the glycolate-glycerate urinary ratio were carried out on all the patients. "
01/01/2011 - "Controls were fed a standard diet and the remaining groups received a 3% glycolate diet for 4 weeks to induce hyperoxaluria. "
09/01/2000 - "Hyperoxaluria may reflect malabsorption although correlation between excretion of oxalate and glycolate suggests a portion of the excess oxalate is derived from metabolic processes. "
09/01/1992 - "Glycolate levels were normal in 5 patients with enteric hyperoxaluria. "
09/01/1992 - "To differentiate hyperoxaluria syndromes we measured plasma and urine glycolate by a novel high performance liquid chromatographic procedure. "
|1.||Gastric Bypass (Roux-en-Y Gastric Bypass)
03/25/2015 - "New causes of hyperoxaluria are arising recently, in particular after gastric bypass surgery, which requires regular and preemptive monitoring. "
09/01/2014 - "Changes in the passive permeability of the intestine, such as in steatorrhoea and following gastric bypass, also promote oxalate absorption and hyperoxaluria. "
09/01/2013 - "Although Roux-en-Y gastric bypass hyperoxaluria appears primarily mediated by gut and diet, secondary causes of oxalogenesis from liver or other mechanisms deserve further exploration."
07/01/2010 - "Hyperoxaluria is a long-term consequence of Roux-en-Y Gastric bypass: a 2-year prospective longitudinal study."
03/01/2010 - "Hypocitraturia and hyperoxaluria after Roux-en-Y gastric bypass surgery."
07/01/2001 - "Enteric hyperoxaluria is a commonly seen adverse event after the jejunoileal bypass procedure. "
12/13/1986 - "Group 2 consisted of 4 patients with enteric hyperoxaluria after intestinal bypass surgery. "
03/01/1983 - "Eleven patients with hyperoxaluria (greater than 0.45 mmol/24 h) after jejunoileal bypass were therefore studied under surgical ward conditions for 5 days. "
02/01/1983 - "These results confirm the current view that in patients with hyperoxaluria secondary to jejunoileal bypass, the majority of urinary oxalate derives from dietary oxalate that is absorbed from the colon. "
02/01/1983 - "Complex pathogenesis of hyperoxaluria after jejunoileal bypass surgery. "
05/01/2014 - "Combined liver-kidney transplantation for hyperoxaluria type II?"
01/01/2007 - "The literature associated with renal transplantation for enteric hyperoxaluria is reviewed."
01/01/2007 - "There have only been a few reports of renal transplantation as treatment of endstage renal disease secondary to enteric hyperoxaluria and results have been mixed. "
03/01/2006 - "Although the risk of recurrence of the disease is very high after renal transplantation, it may be the ultimate therapeutic alternative in secondary hyperoxaluria. "
04/01/2002 - "Living related kidney transplantation in a 15-year-old patient with type I hyperoxaluria: a case report."
01/01/1994 - "Rapid clearance of oxalate after transplant leads to transient hyperoxaluria until normal levels of serum oxalate are reached."
12/01/2015 - "In the first case, oxalate crystals were present by urinalysis months before diagnosis by biopsy; in the second, hyperoxaluria was diagnosed by urine collection immediately after; and in the third, oxalate crystals had been noted incidentally on post-transplant renal biopsy 3 years before the development of fulminant oxalate nephropathy. "
10/01/2014 - "The aim of this review is to underline the causes of hyperoxaluria and the related pathophysiologic mechanisms, which are involved, along with the description of seven cases of irreversible renal graft injury due to secondary hyperoxaluria. "
08/01/2008 - "The possibility of fat malabsorption leading to enteric hyperoxaluria should be considered in renal graft recipients presenting with loose stools and graft dysfunction."
08/01/2008 - "Acute oxalate nephropathy causing late renal transplant dysfunction due to enteric hyperoxaluria."
|5.||Bone Marrow Transplantation (Transplantation, Bone Marrow)