|3.||Dehydration (Water Stress)
|4.||Critical Illness (Critically Ill)
|5.||Neurogenic Diabetes Insipidus (Central Diabetes Insipidus)
|1.||Lindner, Gregor: 9 articles (04/2014 - 12/2007)|
|2.||Schwarz, Christoph: 8 articles (04/2014 - 12/2007)|
|3.||Funk, Georg-Christian: 8 articles (04/2014 - 12/2007)|
|4.||Sam, Ramin: 3 articles (11/2015 - 01/2012)|
|5.||Bradac, Ondrej: 3 articles (07/2015 - 01/2011)|
|6.||Spatenkova, Vera: 3 articles (07/2015 - 01/2011)|
|7.||Hoorn, Ewout J: 3 articles (07/2015 - 05/2007)|
|8.||Sato, Naoki: 3 articles (01/2015 - 12/2013)|
|9.||Kinugawa, Koichiro: 3 articles (01/2015 - 01/2014)|
|10.||Krause, Eric G: 3 articles (09/2014 - 04/2011)|
09/01/2009 - "The use of Normofundin is associated with a risk of a rapid and significant reduction in the level of sodium and that of physiological solution fails to correct hypernatremia. "
03/01/2011 - "Hypernatremia and fluctuations of sodium seem to be related to early severe IVH among preterm infants; however, further studies are required to clarify the causal relationship."
12/01/2004 - "In many previous studies, one or the other forebrain circumventricular organ, the subfornical organ (SFO) or organum vasculosum laminae terminalis (OVLT), was lesioned to test whether it was critical for the behavioral or physiological responses to sodium depletion and hypernatremia. "
12/01/1985 - "During the study period, the mean serum sodium levels exceeded 145 mEq/L (hypernatremia) in 64% of the term and 67% of the preterm infants.(ABSTRACT TRUNCATED AT 250 WORDS)"
11/01/2015 - "Calculation of the theoretical change in MCV at changed P-Sodium/P-Osmolality and to investigate if the automated blood cell counter Sysmex XE 2100 measures MCV correctly in hypo- and hyperosmolality and hypo-and hypernatremia. "
|2.||Glucose (Dextrose)FDA LinkGeneric
12/01/2000 - "Water loss associated with glucose diuresis may necessitate a higher rate of fluid administration in camelids with this syndrome than is typically used for treatment of hypernatremia in calves."
06/01/1986 - "The failure of hypoglycemic mice with hypernatremia and elevated plasma osmolality (range, 416-434 mOsm/kg H2O) to respond to 1 M glucose (30 ml/kg) may have been due to the ill effects of the additional hyperosmolar load. "
03/01/1959 - " The use of glucose, electrolyte, and water solutions prepared at home could not be associated with hypernatremia but the use of a commercial oral electrolyte solution, Lytren, was so associated. "
04/01/2013 - "Acute, symptomatic dysnatremia should be corrected promptly by use of 3 % NaCl for hyponatremia and 5 % glucose for hypernatremia. "
08/01/1975 - "Severe hypernatremia also was present, even though large amounts of 5% glucose solution without salt were given I.V. Food and water were given by nasal gastric gavage and later gavage via gastric fistula, but the hypernatremia remained unchanged. "
01/01/1978 - "Application of vasopressin radioimmunoassay to clinical study: role of vasopressin in hypo- and hypernatremia and some other disorders of water metabolism."
05/01/2013 - "Hypernatremia is encountered after pituitary or hypothalamic surgery and typically is secondary to vasopressin deficiency resulting in increased free water clearance with inadequate water replacement. "
12/01/2008 - "Vasopressin (AVP) deficient homozygous Brattleboro rats exhibit severe osmotic challenges due to waterless chronic hypernatremia and hyperosmolality. "
09/01/2008 - "The role of hypernatremia, serum hyperosmolality, and Vasopressin analogs in the pathology are discussed along with imaging and treatment."
01/01/2006 - "Chronic hypernatremia increases the expression of vasopressin and voltage-gated Na channels in the rat choroid plexus."
04/01/1994 - "Hypernatremia is also a concern for malnourished children, but studies show that WHO's ORS is safe and effective in treating malnourished children. "
04/01/2007 - "Compared to ORS II, ROORS could decrease the intravenous supplement of fluid and lower the risk of hypernatremia."
08/01/1996 - " The risk of hypernatremia with use of the WHO/UNICEF ORS is a concern since infants and young children have an immature renal concentrating capacity, increased insensible water losses, and an impaired natriuretic response. "
03/01/1995 - "Hypernatremia and ORS."
01/01/1990 - " Due to the possibility of excess salt entering the bloodstream (hypernatremia), some pediatricians do not use the WHO recommended ORS in newborns and young infants. "
|5.||Sodium Chloride (Saline Solution)FDA LinkGeneric
07/01/2015 - "In this teaching case, we present a 19-year-old patient in whom severe hypernatremia developed as a result of normal saline solution infusion and explore the pharmacokinetic and pharmacodynamic effects of frequently used infusion fluids. "
06/01/2008 - "[Severe hypernatremia due to sodium chloride intake]."
07/01/1993 - "A similar increase in Posm from 290 to 310 mOsm/kg H2O during hypertonic sodium chloride infusion 11 days following the correction of hypernatremia increased Pavp to 1.95 microU/mL (r = 0.786, P < 0.05). "
07/01/1993 - "Hypertonic sodium chloride infusion to reassess this relationship 2 days following the correction of hypernatremia increased Pavp only to 0.67 microU/mL while increasing Posm from 297 to 316 mOsm/kg H2O. "
03/01/1989 - "This problem develops most often because of loss of water from the animal, but in rare cases hypernatremia results from gain of sodium chloride. "
|6.||Sodium Bicarbonate (Baking Soda)FDA LinkGeneric
08/01/2003 - "Because the infusion of sodium bicarbonate resulted in hypernatremia, the effect of hypernatremia was studied in an additional group that received hypertonic saline. "
02/01/2003 - "Sodium bicarbonate was added to the dialysate in variable concentrations (13 - 34 mmol/l) to control acid-base status and prevent hypernatremia. "
01/01/1984 - "However, infusion of sodium bicarbonate did cause hyperosmolality and hypernatremia and a significant decrease in brain water content. "
01/01/2014 - "We should keep in mind that acute hypernatremia and CPM can be associated with intravenous sodium bicarbonate therapy, and that CPM due to acute hypernatremia may be effectively treated with plasma exchange."
01/01/2014 - "We diagnosed her with CPM associated with the rapid development of hypernatremia after intravenous sodium bicarbonate therapy and treated her with plasma exchange. "
|7.||Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
01/01/2010 - "Our results reveal that treatment of the patient with Desmopressin acetate relieved the adypsia, hypernatremia and hyperosmolality effectively. "
01/01/2010 - "A patient with essential hypernatremia had good response to desmopressin acetate therapy."
09/01/2007 - "Early treatment with desmopressin almost always prevents hypernatremia. "
01/01/2003 - "In the DDAVP treatment group, these changes were not observed, showing that administration of DDAVP (4 microg, installation, twice daily) effectively prevented hypernatremia that develops immediately after surgery and DI-like symptoms that persists for about one week after surgery."
07/01/2002 - "Their clinical courses were generally stable without apparent decline in PFT, except that one patient with a psychiatric problem died from hypernatremia due to misuse of desmopressin. "
09/01/2009 - "The study revealed that the most adequate correction of hypernatremia was seen with the use of Sterofundin. "
09/01/2009 - "[Experience in using normofundin and sterofundin solutions for the correction of hypernatremia]."
09/01/2009 - "The efficacy of Sterofundin, Normofundin, and physiological solutions in correcting hypernatremia and impaired acid-base balance was analyzed in patients with sellar region tumors. "
|9.||Oxytocin (Pitocin)FDA LinkGeneric
01/01/2014 - "Hypernatremia stimulates the secretion of oxytocin (OT), but the physiological role of OT remains unclear. "
02/01/1996 - "At the same time, we found that oxytocin (OT) receptors were important mediators of natriuresis induced by hypernatremia but not of that induced by isotonic volume expansion. "
06/01/1990 - " Saline can be used after 15 weeks, can cause hypernatremia or coagulopathy, and takes up to 72 hours unless augmented with ocytocin and/or laminaria. "
04/06/2011 - "Hypernatremia also completely eliminated the increased plasma renin activity that accompanied restraint in controls, but greatly elevated circulating levels of oxytocin. "
|10.||Heparin (Liquaemin)FDA LinkGeneric
11/01/2000 - "Heparin-free hemodialysis is an effective and safe method in the treatment of hypernatremia in extensively burned patients."
11/01/2000 - "Heparin-free hemodialysis in the treatment of hypernatremia in severely burned patients."
01/01/2012 - "Metabolic alterations during RCA such as metabolic alkalosis, hypocalcemia and hypernatremia are rare and of little clinical impact; their incidence is similar to those reported during CRRT with heparin. "
11/01/2000 - "In two extensively burned patients with burn area of 100% TBSA and 98% TBSA respectively and hypernatremia with serum sodium concentration as high as 169 and 158 mmol/l respectively, heparin-free hemodialysis was performed five times and three times each. "
05/01/1991 - "Release of benzalkonium chloride from a heparin-bonded umbilical catheter with resultant factitious hypernatremia and hyperkalemia."
|1.||Renal Dialysis (Hemodialysis)
01/01/2004 - "We recommend hemodialysis is the best approach to correct severe hypernatremia."
01/01/2014 - "Patient was admitted to medicine intensive care unit and after inadequate response to suboptimal fluid repletion, hemodialysis was used to correct hypernatremia. "
01/01/2014 - "Hypernatremia: correction rate and hemodialysis."
06/01/2013 - "Although the standard treatment for severe hypernatremia is hydration, hemodialysis can be an additional treatment in cases of combined uremic encephalopathy. "
06/01/2013 - "She underwent two sessions of hemodialysis to treat the uremic encephalopathy and hypernatremia, and recovered fully without neurological sequelae. "
|2.||Fluid Therapy (Oral Rehydration Therapy)
01/01/2015 - "Successful management of extreme hypernatremia with only oral rehydration salt did not result in observable neurological consequences, which emphasizes the importance of the use of oral rehydration salt for the clinical management of childhood hypernatremia."
01/01/2015 - "Her hypernatremia was treated exclusively with oral rehydration salt solution. "
07/01/2007 - "Initial rates of correction of hypernatremia were similar with intravenous and oral hypotonic fluid therapy. "
11/01/2006 - "Organic osmolytes accumulated during the adaptation to hypernatremia are slow to leave the cell during rehydration. "
05/01/1998 - "Initial fluid therapy should be given with care according to the rate of onset of hypernatremia, as deterioration of the animal's condition is a common sequela. "
12/01/2013 - "Previous studies have suggested donor hypernatremia results in a greater incidence of early postoperative graft dysfunction in liver transplant and is considered one of the extended criteria donor. "
08/27/2010 - "This study analyzes early graft function for donor livers procured from patients with severe hypernatremia. "
09/01/1999 - "The aim of this study is to determine whether donor hypernatremia is associated with early graft dysfunction after OLT and to determine the effect of the correction of donor hypernatremia. "
08/01/2015 - "In conclusion, donor hypernatremia just before procurement does not appear to have negative effects on mortality and graft failure rates at 30 days following pediatric LT."
03/01/2015 - "Furthermore, the percentage of successful graft function when transplanted into diabetic NOD Scid mice was significantly lower in the hypernatremia (42%) group compared with the normal control (85%) group (P<0.001). "
|4.||Homologous Transplantation (Allograft)
12/01/2013 - "This study sought to show the negative effect donor hypernatremia has on initial liver allograft function. "
11/01/2002 - "The effect of hypernatremia on liver allografts in rats."
09/01/1999 - "Recipients of hepatic allografts from donors with uncorrected hypernatremia had a significantly greater incidence of graft loss compared with recipients of hepatic allografts from normonatremic donors. "
01/01/2008 - "DeltaNa(+) as well as donor hypernatremia and recipient hyponatremia were not found to be associated with immediate postoperative allograft function, intraoperative blood product usage, LOICUS, LOHS or short-term patient survival. "
01/01/2008 - "Influence of hypernatremia and polyuria of brain-dead donors before organ procurement on kidney allograft function."
|5.||Transplantation (Transplant Recipients)
08/01/2015 - "Our aim was to use the Scientific Registry of Transplant Recipients database to evaluate the effects of donor hypernatremia on 30-day outcomes in pediatric LT recipients. "
03/01/2015 - "Organs from hypernatremia (elevated Na+) donors when used for transplantation have had dismal outcomes. "
09/01/2009 - "This study aimed to characterize donors according to gender, age group, cause of brain death; quantify donors with hypernatremia, hyperpotassemia and hypopotassemia; and get to know which organs were the most used in transplantations. "
03/01/2013 - "Here, we describe a case of a kidney transplant recipient with CUA and moderately declined kidney function who was treated with sodium thiosulfate and developed important hypernatremia and high anion gap acidosis necessitating significant reduction in dosing."
02/01/2015 - "Although sodium levels increased during the observation, rates of hypernatremia were comparable between hemodialysis days 1 and 5. Hemodialysis using regional citrate anticoagulation remains a challenge in the perioperative care of liver transplant recipients. "