Hyperlipidemias (Hyperlipidemia)

03/01/2005 - "The aim of this study was to evaluate the efficacy of current lipid-lowering 10 regimens, and to provide the best possible therapeutic strategies for patients with hyperlipidemia by identifying risk factors for the development of CHD, based on the current JAS recommendations. "
02/01/2023 - "However, most clinical lipid-lowering drugs have adverse effects and cannot achieve the desired efficacy in some complex hyperlipidemia patients, so it is of great significance to develop safe and effective novel lipid-lowering drugs. "
01/01/2013 - "Most patients with hyperlipidemia showed improvement or resolution of lipid profiles after LSG. "
01/01/2023 - "PROMPT-LIPID evaluated if automated electronic alerts to physicians with guideline-based recommendations improved the management of hyperlipidemia in patients at very high risk. "
10/06/2020 - "Moreover, we have corroborated the potent lipid-lowering efficacy of IPA both in vitro and in vivo These findings not only indicate a potential mechanism by which gut microbes and their metabolites confer the beneficial role of DNJ in ameliorating hyperlipidemia but also provide an in-depth theoretical basis for therapeutic exploitation of DNJ as a female-specific intervention against hyperlipidemia."

06/01/2014 - "The multigrain diet used in the present study is effective in countering the hyperlipidemia and oxidative stress caused by high cholesterol intake."
11/18/2020 - "Probiotics improved hyperlipidemia in mice induced by a high cholesterol diet via downregulating FXR."
04/20/2017 - "Our results suggest that HVC1 might be effective in preventing high-cholesterol diet-induced hyperlipidemia by regulating the genes involved in cholesterol and lipid metabolism, and inflammatory responses."
03/01/2017 - "The immunological evidence confirms the significant cholesterol-lowering effect of RO, suggesting its potential as a novel therapeutic agent for hyperlipidemia and associated immune decline."
01/01/2016 - "Compared with the high-cholesterol high-fat (HCHF) group, the rats in the HCHF+ZSO group showed improved levels of hyperlipidemia indicators. "

04/23/2014 - "Statins are the most commonly prescribed drugs in the United States and are extremely effective in reducing major cardiovascular events in the millions of Americans with hyperlipidemia. "
01/01/2019 - "The study will recruit 900 participants from 8 centers, and aims to determinate the prevalence of abnormal postprandial lipemia in patients at high- and very high-risk for CV disease, the efficacy of statin treatment and other medications on postprandial lipemia, and the interaction between postprandial lipemia and CV risk during a treatment period of 3 years. "
10/01/2012 - "Statin use was associated with a significant reduction in the risk of OAG among persons with hyperlipidemia. "
03/01/2007 - "There are some reports in which the significance of treatment of hyperlipidemia was examined: statin treatment appears beneficial for young-old people, while treatment of hyperlipidemia appears no longer beneficial for old-old people. "
10/01/2002 - "Although statins have been shown to be beneficial in the management of hyperlipidemia and the reduction of cardiovascular morbidity and mortality, rates of major cardiovascular events remain high despite their use. "

01/21/1989 - "A marked decrease (-36%) of plasma triglycerides was observed in 12 subjects with IIb hyperlipidemia. "
02/05/2020 - "Here, we investigated the efficacy of BL on postprandial hyperlipidemia in subjects with high fasting triacylglycerol (TG) concentrations. "
05/01/1992 - "Triglycerides above 275 mg per dL caused a significant reduction in measured activity of DAO; however, this effect could be eliminated by use of ultracentrifugation to remove lipemia. "
01/01/1986 - "The decreased clearance of circulating triglycerides appears to be the major mechanism contributing to hyperlipemia. "
01/01/1984 - "The decreased clearance of circulatory triglycerides appears to be the major mechanism contributing to hyperlipemia. "

07/01/1999 - "In the preliminary study, along with a rapid improvement of hyperlipidemia, a high incidence of remission was achieved by LDL-A performed at relatively short intervals. "
05/01/2016 - "There was a significant reduction in LDL-CH in the control + EHP group and the hyperlipidemia + EHP group (P < 0.05). "
03/01/2018 - "Serum samples from a large population study (n = 12284 subjects) were used to generate reference intervals for LDL-TG and to determine levels in various types of hyperlipidemia. "
11/01/2017 - "In this study, we utilized Ox-LDL-treated H9c2 cardiomyoblast cells as a simulated hyperlipidemia model. "
04/23/2015 - "This study demonstrates that oxLDL and hyperlipidemia stimulate the generation of NOX2-derived ROS through a CD36-PKC pathway and may promote platelet hyperactivity through modulation of cGMP signaling. "

01/01/2020 - "Surgical remission with concomitant control of impaired glucose metabolism at diagnosis may have significant implications for controlling hyperlipidemia and reducing cardiovascular risk in CD."
03/01/1991 - "In addition to the hypolipemic effect, the methanolic extract was also shown to be effective in reducing an elevated level of glucose in rats with hyperlipemia resulting from high-fat feeding. "
01/11/2021 - "Overall, the consumption of flaxseeds produced moderate reduction in glucose levels and hyperlipidemia, together with improvement in the impaired organs' function in diabetic rats. "
04/30/1986 - "The optical aberrations due to the presence of the turbidity caused by hyperlipidemia has been eliminated in two serum glucose procedures. "
02/27/2023 - "The present study was proposed to evaluate its effects on glucose metabolism and other associated processes, such as lipemia and adipogenesis, as well as, to evaluate its effects on the liver, pancreas, and aorta in subjects fed with an occidental high-fat diet (HFD). "

01/01/2007 - "Moreover atorvastatin improved although not completely normalized parameters of postprandial lipemia: significant lowering of baseline (-17%), 3 (-19%) and 6 hour (-14%) post load TG levels was noted. "
02/01/2015 - "Acupuncture combined with administration of Lipitor is effective in improving primary hyperlipidemia in patients, which is superior to administration of simple Lipitor."
10/01/2002 - "Is alternate daily dose of atorvastatin effective in treating patients with hyperlipidemia? "
07/01/2002 - "In conclusion, low-dose atorvastatin appears to be safe, well tolerated, and effective in the treatment of post-transplant hyperlipidemia. "
12/01/2003 - "The use of atorvastatin in NASH patients with hyperlipidemia was found to be both effective and safe. "

11/01/1998 - "The TG responses in plasma and TG-rich-lipoprotein (TRL) (d <1.006) after the oral fat load were significantly greater in NIDDMs with nephropathy compared to controls or NIDDMs without nephropathy, while such a marked postprandial lipemia was not observed in patients with primary renal disease. "
08/01/2018 - "Previous study indicated that sitosterolemic patients might be vulnerable to post-prandial hyperlipidemia, including high remnant-like lipoprotein particles (RLP) level. "
01/01/2013 - "Depending on study aims, for the use of the model it may be beneficial to perform single-dose assessments at time points later than 36 h when the lipoprotein concentrations will be more similar to those seen in patient with hyperlipidemia."
02/01/2006 - "The objective of this study was to investigate the lipoprotein profiles in Wistar rats and New Zealand white rabbits with experimentally induced hyperlipidemia by means of ultracentrifugation. "
10/15/2001 - "This study indicates that for renal transplant patients in whom RAPA treatment induces hyperlipidemia, this effect is the result of reduced catabolism of apoB100-containing lipoproteins."

03/01/2019 - "These results suggested that p-CA is a potent antioxidant with potential therapeutic efficacy for treating hyperlipidemia symptoms."
03/04/2015 - "The in vitro, in silico and in vivo results clearly demonstrated the antioxidant potential and therapeutic efficacy of the inhibitor as an alternate drug against hyperlipidemia."
12/01/2012 - "In mice, induction of hyperlipidemia worsened diaphragmatic oxidative stress during MV, whereas transgenic overexpression of a mitochondria-localized antioxidant (peroxiredoxin-3) was protective against VIDD. "
12/01/2018 - "When combined with hyperlipidemia and limited antioxidant activity, the fetus suffers from hepatic oxidative stress and altered intracellular metabolism which can be improved with maternal diet intervention. "
12/13/2017 - "Fermented soymilk also improved antioxidant capacities of hyperlipidemia rats. "

04/01/2006 - "The polymorphism of human IFABP gene in hyperlipidemia is related with the therapeutic efficacy of fenofibrate, and the T54T IFABP genotype may have strong negative effect on such efficacy."
07/01/2021 - "Over 21 to 63 days, TriCor was effective in the management of primary and secondary hyperlipidemia in dogs."
01/01/1989 - "The first well-controlled studies of fenofibrate in the United States indicate that the drug is safe and effective for the treatment of type IIa and type IIb hyperlipidemia. "
07/01/2021 - "To investigate the efficacy of a micronized, nanocrystal formulation of fenofibrate (Tricor) in the treatment of hyperlipidemia in dogs. "
07/01/2021 - "Efficacy of a micronized, nanocrystal fenofibrate formulation in treatment of hyperlipidemia in dogs."

05/01/1997 - "Dietary therapy was dramatically effective for the treatment of hyperlipidemia in patients with apo E7. "
03/01/1977 - "Among the tested drugs administered in a course of therapy of 4 weeks atromidine proved to be most effective for the examined types of hyperlipidemia (IIa, IIb, IV). "
12/04/2020 - "This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of hyperlipidemia, and may be helpful for clinicians, hyperlipidemia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of hyperlipidemia. "
05/01/2005 - "A number of studies,however, have shown that aggressive control of blood pressure and hyperlipidemia and the institution of antithrombotic therapy are beneficial in reducing the risk of CV events in the diabetic patient. "
01/01/2020 - "Effective and safe alternative and adjunctive therapies could be beneficial for patients with hyperlipidemia. "

04/01/2011 - "For example, glycemic control and hyperlipidemia should be improved with diet, exercise, and medications. "
01/01/2021 - "To achieve and maintain guideline-recommended glycemic control, care delivery models must put additional emphasis and effort on patients with longer disease duration, younger people and those having microvascular complications and hyperlipidemia."
01/01/2021 - "Further, longer duration of diabetes (>15 years), RR: 1.41; 95% CI: 1.15, 1.72, hyperlipidemia, RR: 1.19; 95% CI: 1.06, 1.34 and younger age group (35-49 years vs. >64 years: RR: 0.61; 95% CI: 0.47-0.79) were associated with persistently poor glycemic control (HbA1c > 9%). "
06/01/2018 - "Poor glycemic control, hyperlipidemia, smoking, oxidative stress, accumulation of advanced glycated end products, environmental, genetic and epigenetic factors play an important role in the pathophysiological development of DN. "
01/01/2017 - "Consistency of glycemic control and management of postprandial glycemia and lipidemia are important to preserve kidney function in type 2 diabetic patients."

04/01/2015 - "Indications for apheresis as an ultima ratio treatment of refractory hyperlipidemias."
02/01/2003 - "Micro- and macrocirculatory effects of apheresis in patients with familial hyperlipidemia."
07/01/1992 - "Hyperlipidemia was rapidly corrected after the initial two aphereses, whereas clinical signs of arteriosclerosis obliterans (ASO), such as coldness of the legs in 17 of 19 patients (89.5%), intermittent claudication in 14 of 17 patients (82.4%), foot pain at rest in 15 of 18 patients (83.3%), poor arterial pulsation in 12 of 16 patients (75.0%), and diminution of ulcer/necrosis in 3 of 5 patients (60.0%), improved in parallel. "
02/01/2010 - "LDL-apheresis could be the first line treatment of isolated hyperLp(a)lipidemia when CAD is established. "
06/01/2011 - "This study aimed to investigate whether LDL apheresis was capable of reducing oxidative and atherogenic markers in uremic patients with hyperlipidemia. "

05/01/2010 - "Besides drug therapy, a number of medicinal plants are effective in treating hyperlipidemia. "
05/15/1993 - "While diet is the mainstay of treatment for hyperlipidemia, drug therapy is necessary to achieve treatment goals in certain patients. "
08/01/1997 - "Regardless of the drug therapy used, the cornerstone treatment for hyperlipidemia is dietary changes. "
05/01/2019 - "4. These consistent findings across studies in HL rats suggest more studies are needed at the clinical level for optimal pharmacotherapies for hyperlipidemia."
08/15/2011 - "Intervention strategies (dietary and exercise advice, treatment switching, and pharmacotherapy) are required for persistent hyperlipidemia and should be assessed in randomized control trials."

01/01/2022 - "The classic traditional Chinese medicine (TCM) prescription Danshen decoction (DSD) has been found effective for the treatment of hyperlipidemia. "
10/01/2015 - "[Study on mechanism for anti-hyperlipidemia efficacy of rhubarb through assistant analysis systems for acting mechanisms of traditional Chinese medicine]."
06/20/2015 - "Use of traditional Chinese medicine in patients with hyperlipidemia: A population-based study in Taiwan."
04/12/2011 - "Therefore, this study supports its ethnopharmacological use in Traditional Chinese Medicine to manage hyperlipidemia and paves a basis for establishing quality control method of Chinese medicine."
11/15/2023 - "Xiongdanjiuxin pill (XP) is a traditional Chinese medicine formula for the prevention and treatment of hyperlipidemia (HLP) and related complications. "