|2.||Wernicke Encephalopathy (Wernicke's Encephalopathy)
|3.||Neurologic Manifestations (Neurological Manifestations)
|1.||Yoneyama, Yoshio: 7 articles (08/2006 - 10/2002)|
|2.||Tan, Peng Chiong: 6 articles (06/2014 - 10/2006)|
|3.||Suzuki, Shunji: 6 articles (03/2006 - 10/2002)|
|4.||Araki, Tsutomu: 6 articles (02/2005 - 10/2002)|
|5.||Omar, Siti Zawiah: 5 articles (06/2014 - 10/2006)|
|6.||Sawa, Rintaro: 5 articles (02/2005 - 10/2002)|
|7.||Otsubo, Yasuo: 4 articles (02/2003 - 10/2002)|
|8.||Matsubara, Shigeki: 3 articles (01/2015 - 08/2009)|
|9.||Guttuso, Thomas: 3 articles (10/2014 - 01/2010)|
|10.||Omar, Siti Z: 3 articles (04/2011 - 08/2007)|
|1.||Metoclopramide (Reglan)FDA LinkGeneric
04/01/2011 - "Metoclopramide is effective in NVP and hyperemesis gravidarum, with a good balance of efficacy and tolerability. "
09/01/2000 - "metoclopramide appears to be a safe, effective treatment for hyperemesis gravidarum. "
09/01/2000 - "metoclopramide for treatment of hyperemesis gravidarum were identified from a national database. "
09/01/2000 - "To describe the use of subcutaneous (s.c.) metoclopramide in the outpatient treatment of hyperemesis gravidarum. "
09/01/2000 - "Home subcutaneous metoclopramide therapy for hyperemesis gravidarum."
10/01/1998 - "The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study."
04/01/2003 - "Successful treatment of recurrent, intractable hyperemesis gravidarum with methylprednisolone. "
05/01/1998 - "Patients with intractable hyperemesis gravidarum were candidates for oral methylprednisolone. "
05/01/1998 - "Our purpose was to describe the effect of oral methylprednisolone on the course of refractory hyperemesis gravidarum. "
05/01/1998 - "Experience with oral methylprednisolone in the treatment of refractory hyperemesis gravidarum."
|3.||Prednisolone (Predate)FDA LinkGeneric
02/01/1996 - "High-dose prednisolone therapy is effective in suppressing symptoms of intractable hyperemesis gravidarum and allowing normal maternal nutrition."
03/01/2004 - "To determine whether low dosages of prednisolone are effective in the treatment of outpatients with hyperemesis gravidarum. "
03/01/2004 - "The efficacy low dose of prednisolone in the treatment of hyperemesis gravidarum."
03/01/2004 - "Maintaining glycaemic control during high-dose prednisolone administration for hyperemesis gravidarum in Type 1 diabetes."
03/01/2002 - "To document the effect of prednisolone therapy in women with defined severity of hyperemesis gravidarum. "
|4.||gabapentin (Neurontin)FDA LinkGeneric
10/01/2014 - "Gabapentin is currently FDA-approved for treating RLS and preliminary results have shown it may be effective for treating the most severe form of NVP, hyperemesis gravidarum (HG). "
11/01/2012 - "A case of treatment refractory hyperemesis gravidarum in a patient with comorbid anxiety, treated successfully with adjunctive gabapentin: a review and the potential role of neurogastroentereology in understanding its pathogenesis and treatment."
11/01/2015 - "Gabapentin use has also been recommended for hyperemesis gravidarum and restless leg syndrome in pregnant mothers. "
01/01/2010 - "Gabapentin use in hyperemesis gravidarum: a pilot study."
01/01/2010 - "Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. "
|5.||Adrenal Cortex Hormones (Corticosteroids)IBA
01/01/2001 - "To assess the efficacy of corticosteroids in the treatment of severe hyperemesis gravidarum refractory to conventional management. "
01/01/2003 - "Randomised, double-blind, placebo-controlled trial of corticosteroids for the treatment of hyperemesis gravidarum."
01/01/2001 - "Randomised, double-blind, placebo-controlled trial of corticosteroids for the treatment of hyperemesis gravidarum."
04/01/2011 - "The role of corticosteroids for hyperemesis gravidarum remains controversial. "
12/01/2003 - "The addition of parenteral and oral corticosteroids to the treatment of women with hyperemesis gravidarum did not reduce the need for rehospitalization later in pregnancy."
|6.||Promethazine (Promet)FDA LinkGeneric
10/01/1998 - "The study compared the efficacy of methylprednisolone with that of promethazine for the treatment of hyperemesis gravidarum. "
05/01/1996 - "This preliminary trial of ondansetron demonstrated no benefit over promethazine in patients hospitalized for hyperemesis gravidarum."
05/01/2010 - "Promethazine and metoclopramide have similar therapeutic effects in patients who are hospitalized for hyperemesis gravidarum. "
05/01/2010 - "To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum. "
05/01/2010 - "Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial."
|7.||Hydrocortisone (Cortisol)FDA LinkGeneric
11/01/2006 - "A short course of hydrocortisone is an effective treatment for intractable hyperemesis gravidarum."
11/01/2006 - "The purpose of this study was to compare the efficacy of pulsed hydrocortisone therapy with that of metoclopramide for the management of intractable hyperemesis gravidarum. "
01/01/1976 - "In order to study the function of the pituitary-adrenal axis, serum ACTH and cortisol levels were estimated before and after insulin induced hypoglycaemia in nine women with hyperemesis gravidarum, seven women in normal early pregnancy and in eight non-pregnant controls. "
08/01/2006 - "In the group with hyperemesis gravidarum, an inverse correlation was detected between cortisol and leptin (r = -0.762, P < 0.01), and hCG and thyroid-stimulating hormone (r = -0.503, P < 0.05), whereas a significant correlation was detected between insulin and leptin (r = 0.538, P < 0.05), leptin and BMI (r = 0.711, P < 0.01), and between TT3 and hCG (r = 0.605, P < 0.01). "
|8.||Clonidine (ST 155)FDA LinkGeneric
|9.||Thiamine (Aneurin)FDA Link
02/01/2013 - "In the setting of hyperemesis gravidarum, an acute deficiency of thiamine results from body stores being unable to meet increased metabolic demands. "
02/01/2012 - "Hyperemesis gravidarum can impair correct absorption of an adequate amount of thiamine and can cause electrolyte imbalance. "
06/01/2011 - "Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke's encephalopathy."
04/01/2006 - "We also underline the necessity to promptly replace vitamin B1 when neurologic symptoms and/or signs develop in a patient with hyperemesis gravidarum."
09/01/2005 - "A thiamine therapy similar to the one reported in this article could prove useful in long-lasting hyperemesis gravidarum complicated by Wernicke's encephalopathy."
|10.||Adrenocorticotropic Hormone (ACTH)FDA Link
01/01/2000 - "The results of the trial using adrenocorticotropic hormone to treat hyperemesis gravidarum show no evidence of benefit. "
01/01/1979 - "Thirty-two women with hyperemesis gravidarum were treated with intramuscular ACTH (0.5 mg) or placebo for 4 days in a randomized double-blind trial. "
01/01/1979 - "Intramuscular ACTH or placebo in the treatment of hyperemesis gravidarum."
01/01/1976 - "The high ACTH level might be evidence of the psychia instability of hyperemesis gravidarum patients."
12/31/1958 - "[Further results of adrenocorticotrophic hormone therapy of hyperemesis gravidarum]."
09/01/2007 - "Nei-Guan point acupressure is a useful treatment for relieving symptoms experienced by women with hyperemesis gravidarum."
06/01/2005 - "[The effect of P6 acupressure for symptom control in pregnant women having hyperemesis gravidarum]."
06/01/1997 - "Acupressure for hyperemesis gravidarum."
02/01/2004 - "The aim of this study was to evaluate the antiemetic effect of acupuncture (AP) and acupressure (APr) of the Pc 6 acupoint in pregnant women with hyperemesis gravidarum (HG). "
02/01/2004 - "Success of acupuncture and acupressure of the Pc 6 acupoint in the treatment of hyperemesis gravidarum."
04/01/2008 - "Herein we report two cases of hyperemesis gravidarum successfully treated with an effective regimen of peripheral parenteral nutrition."
04/01/2008 - "Peripheral parenteral nutrition in protracted hyperemesis gravidarum--report of two cases and a literature review."
08/30/1996 - "Nasoenteral nutrition ought to be considered as an alternative to parenteral nutrition for treatment of hyperemesis gravidarum."
01/01/1996 - "Management strategies for hyperemesis gravidarum, including hydration, enteral and parenteral nutrition, antiemetic therapies, monitoring needs, and psychosocial concerns are discussed with applications made to the home care setting."
05/01/1993 - "Three pregnant patients required parenteral nutrition for refractory hyperemesis gravidarum. "
|3.||Fluid Therapy (Oral Rehydration Therapy)
08/01/1995 - "Women who present to the ED with hyperemesis gravidarum are significantly dehydrated and experience measurable improvement in postural pulse rate and systolic BP changes with rehydration. "
11/01/2007 - "Severe NVP (Hyperemesis gravidarum) affects < 1% of women and in some severe cases can require hospitalization and rehydration of fluids. "
06/15/2014 - "Women with hyperemesis gravidarum may require more aggressive interventions, including hospitalization, rehydration therapy, and parenteral nutrition. "
06/01/2014 - "We investigated thyroid function and the impact of gestational transient thyrotoxicosis (GTT) on pregnancy outcome in patients with hyperemesis gravidarum (HG; n = 143) who were hospitalized for rehydration. "
04/01/2009 - "Generally, gestational transient thyrotoxicosis does not require medication, unless if hyperemesis gravidarum is present, thus the patient has to be hospitalized to receive intravenous rehydration, electrolyte correction and antiemetic medication. "
|4.||Enteral Nutrition (Feeding, Tube)
06/01/1992 - "Although clinical experience is limited and further research is needed, early results suggest that enteral nutrition in hyperemesis gravidarum is an effective and safe technique."
04/01/2015 - "To investigate maternal and fetal outcome in hyperemesis gravidarum comparing enteral tube feeding of the mothers with other fluid/nutrition regimens. "
04/01/2015 - "Hyperemesis gravidarum, nutritional treatment by nasogastric tube feeding: a 10-year retrospective cohort study."
11/01/2013 - "We report a case of assisted feeding tube tip location using real time sonography in a pregnant women treated for hyperemesis gravidarum. "
10/01/2001 - "Enteral nutrition by nasojejunal tube in hyperemesis gravidarum."
01/01/2010 - "Studies describing hypnosis in the treatment of hyperemesis gravidarum (HG) were reviewed. "
12/01/1999 - "This article reviews the empirical studies of medical hypnosis for treating hyperemesis gravidarum, explains basic concepts, and details the treatment mechanisms. "
01/01/2010 - "Hypnosis for hyperemesis gravidarum."
12/01/1999 - "It is suggested that medical hypnosis should be considered as an adjunctive treatment option for those women with hyperemesis gravidarum. "
12/01/1999 - "Medical hypnosis for hyperemesis gravidarum."