Hygromycin B

03/01/1989 - "MHV persistence in LM-K cells, which normally involves a steady state infection of 0.1 to 1% of the cells in culture, was found to be cured by hygromycin B treatment, as measured by the elimination of infectious virus from the supernatant medium. "
03/01/2003 - "Use of Coniothyrium minitans transformed with the hygromycin B resistance gene to study survival and infection of Sclerotinia sclerotiorum sclerotia in soil."
07/01/1998 - "These results demonstrate that HIV-1 infection renders cells more sensitive to hygromycin B than uninfected cells, and provides support for the hypothesis that HIV-1 induces an alteration of plasma membrane permeability. "
07/01/1998 - "Hygromycin B also inhibited HIV-1 production in a dose-dependent manner during acute infection. "
10/01/1990 - "HIV replication after infection of the CD4-receptor-bearing HeLa-T4+ cells with HIV-1 was found to be strongly reduced when drug-selected cells cotransfected with pU3R-III/2-5AS and a hygromycin B resistance gene containing plasmid were used. "

01/01/2011 - "Surprisingly, co-expression of SYT2 and HYG(R) caused hypersensitivity of the transgenic Arabidopsis plants to hygromycin B. "
04/01/2010 - "Thus, our results support linkage between severe hypersensitivity to hygromycin B and vacuolar defects."
04/01/2010 - "We hypothesized that such severe hypersensitivity to hygromycin B (hhy) is linked to vacuolar defects and performed a genomic screen for the phenotype using a haploid deletion strain library of non-essential genes. "
04/01/2010 - "Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae."
01/01/2021 - "Furthermore, hypersensitivity to hygromycin B and various ions in addition to the abnormal vacuolar morphology in the syn8Δ mutant suggested that active vacuolar function is required for biofilm formation of C. "

02/01/1967 - "[Hygromycin B in swine ascariasis (review of the literature and original studies)]."
09/01/1967 - "[A test of hygromycin B in ascariasis and heterakiasis in chickens]."

08/01/1969 - "[Intranuclear inclusions in chicken brain neurons upon experimental poisoning with hygromycin B]."
05/01/1969 - "[Clinical and pathomorphological changes in hygromycin B poisoning of chickens]."

09/01/1981 - "Cortical cataracts induced by hygromycin B in swine."
07/01/1983 - "This type of damage was more typical of that seen previously for cataracts induced by cytochalasin D, elevated glucose and hygromycin B."