Hydroxybutyrates

Salts and esters of hydroxybutyric acid.

Also Known As:

Hydroxybutyric Acid Derivatives; Hydroxybutyric Acids; Acid Derivatives, Hydroxybutyric

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxybutyrates: 6
  - Acyclic Acids
    - Butyrates: 2613
      - Hydroxybutyrates: 6
        3-Hydroxybutyric Acid: 934
        Sodium Oxybate: 642
        teriflunomide: 442
        4-hydroxybutyric acid: 177
        acetyl acetonate: 35
        2-hydroxybutyric acid: 25
        lithium hydroxybutyrate: 23
        2-methyl-3-hydroxybutyric acid: 14
        3-hydroxyisobutyric acid: 10
        N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide: 8
        2-hydroxyisobutyric acid: 6
        3-Hydroxyisobutyric aciduria: 6
        (R)-3-hydroxybutyl (R)-3-hydroxybutyrate: 3
        2,2-dimethyl-3-hydroxybutyric acid: 3
        3,4-dihydroxybutanoic acid: 2
        3-hydroxybutyrate methyl ester: 2
        acetylacetonate-poly(L-lactic Acid): 2
        butoctamide succinate: 2
        N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-cyanophenyl)(methyl)amino)-2-hydroxy-2-methylpropanamide: 2
        poly(hydroxybutyrate-co-hydroxyvalerate): 2
        thrazarine: 2
        butoctamide: 1
        ethyl 3-hydroxybutyrate: 1
        SKLB-23bb: 1
        T 8581: 1
        (5-formylfuran-2-yl)methyl 4-hydroxy-2-methylenebutanoate
        (S)-(-)-4-(2-benzimidazolyl)-4-hydroxybutyric acid
        (S)-3,4-dihydroxybutyric acid
        2,3,4-trihydroxybutanamide
        2,4-di-O-acetyl-3-deoxy-glycero-tetronic acid
        2-(1-(3-(4-(biphenyl-4-carbonyl)-2-propylphenoxy)propyl)-1,2,3,4-tetrahydroquinolin-5-yloxy)-2-methylpropionic acid
        2-amino-4-(3'-hydroxyphenyl)-4-hydroxybutanoic acid
        2-ethyl-2-hydroxybutyric acid
        2-hydroxy-3-butynoic acid
        2-hydroxy-4-phosphonobutyric acid
        2-keto-4-hydroxybutyrate
        3,6-(3-hydroxy-5-oxa-1,4-dioxo-6-phenyl-2-hexenyl)-4(1H)-quinolinone
        3-carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
        3-hydroxy-2,2-dimethylbutyrate
        3-hydroxy-3-cyclohexylbutyric acid
        4-(1,3-dibenzyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoic acid
        4-(1-(4-fluorobenzyl)-4-hydroxy-1H-indol-3-yl)-2-hydroxy-4-oxobut-2-enoic acid
        4-(4-(2'-fluorobiphenylyl))-4-hydroxycrotonic acid
        4-(p-biphenylyl)-3-hydroxybutyric acid
        4-arsono-2-hydroxybutanoic acid
        4-chloro-3-hydroxybutyric acid
        4-hydroxy-2-butenoic acid
        4-hydroxy-3-oxobutyrate
        4-hydroxy-4-(3-pyridyl)butanoic acid
        4-pyridyl-2-oxo-4-hydroxyisovaleric acid
        6-tuliposide B
        alpha-aceto-alpha-hydroxybutyrate
        asparaginol
        beta-hydroxy-alpha-ketobutyric acid
        beta-hydroxybutyrate-1,3-butanediol monoester
        ethyl (2S,3S)-3-hydroxy-2-methylbutanoate
        ethyl 3-hydroxy-2-oxobutanoate
        ethyl 3-methyl-3-hydroxy-2-oxobutanoate
        ethyl 4,4,4-trifluoro-3-hydroxybutanoate
        gamma-(4-methoxybenzyl)-gamma-hydroxybutyric acid
        harzianic acid
        HX0969
        hydroxy wilfordic acid
        L-742,001
        methyl alpha-hydroxyisobutyrate
        methyl-4-bromo-3-hydroxybutyrate
        pantoic acid
        phenyl-gamma-methylmercapto-alpha-hydroxybutyrate
        phenytoin-bis-hydroxyisobutyrate
        technetium Tc 99m 2-ethyl-2-hydroxybutyric acid
        technetium Tc 99m 2-hydroxyisobutyric acid
        thiotetronic acid
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Butyrates: 2613
      - Hydroxybutyrates: 6
        3-Hydroxybutyric Acid: 934
        teriflunomide: 442
        4-hydroxybutyric acid: 177
        acetyl acetonate: 35
        2-hydroxybutyric acid: 25
        lithium hydroxybutyrate: 23
        2-methyl-3-hydroxybutyric acid: 14
        3-hydroxyisobutyric acid: 10
        N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide: 8
        2-hydroxyisobutyric acid: 6
        3-Hydroxyisobutyric aciduria: 6
        (R)-3-hydroxybutyl (R)-3-hydroxybutyrate: 3
        2,2-dimethyl-3-hydroxybutyric acid: 3
        3,4-dihydroxybutanoic acid: 2
        3-hydroxybutyrate methyl ester: 2
        acetylacetonate-poly(L-lactic Acid): 2
        butoctamide succinate: 2
        N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-cyanophenyl)(methyl)amino)-2-hydroxy-2-methylpropanamide: 2
        poly(hydroxybutyrate-co-hydroxyvalerate): 2
        thrazarine: 2
        butoctamide: 1
        ethyl 3-hydroxybutyrate: 1
        SKLB-23bb: 1
        T 8581: 1
        (5-formylfuran-2-yl)methyl 4-hydroxy-2-methylenebutanoate
        (S)-(-)-4-(2-benzimidazolyl)-4-hydroxybutyric acid
        (S)-3,4-dihydroxybutyric acid
        2,3,4-trihydroxybutanamide
        2,4-di-O-acetyl-3-deoxy-glycero-tetronic acid
        2-(1-(3-(4-(biphenyl-4-carbonyl)-2-propylphenoxy)propyl)-1,2,3,4-tetrahydroquinolin-5-yloxy)-2-methylpropionic acid
        2-amino-4-(3'-hydroxyphenyl)-4-hydroxybutanoic acid
        2-ethyl-2-hydroxybutyric acid
        2-hydroxy-3-butynoic acid
        2-hydroxy-4-phosphonobutyric acid
        2-keto-4-hydroxybutyrate
        3,6-(3-hydroxy-5-oxa-1,4-dioxo-6-phenyl-2-hexenyl)-4(1H)-quinolinone
        3-carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
        3-hydroxy-2,2-dimethylbutyrate
        3-hydroxy-3-cyclohexylbutyric acid
        4-(1,3-dibenzyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoic acid
        4-(1-(4-fluorobenzyl)-4-hydroxy-1H-indol-3-yl)-2-hydroxy-4-oxobut-2-enoic acid
        4-(4-(2'-fluorobiphenylyl))-4-hydroxycrotonic acid
        4-(p-biphenylyl)-3-hydroxybutyric acid
        4-arsono-2-hydroxybutanoic acid
        4-chloro-3-hydroxybutyric acid
        4-hydroxy-2-butenoic acid
        4-hydroxy-3-oxobutyrate
        4-hydroxy-4-(3-pyridyl)butanoic acid
        4-pyridyl-2-oxo-4-hydroxyisovaleric acid
        6-tuliposide B
        alpha-aceto-alpha-hydroxybutyrate
        asparaginol
        beta-hydroxy-alpha-ketobutyric acid
        beta-hydroxybutyrate-1,3-butanediol monoester
        ethyl (2S,3S)-3-hydroxy-2-methylbutanoate
        ethyl 3-hydroxy-2-oxobutanoate
        ethyl 3-methyl-3-hydroxy-2-oxobutanoate
        ethyl 4,4,4-trifluoro-3-hydroxybutanoate
        gamma-(4-methoxybenzyl)-gamma-hydroxybutyric acid
        harzianic acid
        HX0969
        hydroxy wilfordic acid
        L-742,001
        methyl alpha-hydroxyisobutyrate
        methyl-4-bromo-3-hydroxybutyrate
        pantoic acid
        phenyl-gamma-methylmercapto-alpha-hydroxybutyrate
        phenytoin-bis-hydroxyisobutyrate
        technetium Tc 99m 2-ethyl-2-hydroxybutyric acid
        technetium Tc 99m 2-hydroxyisobutyric acid
        thiotetronic acid

Experts

1.	Hermans, M P: 1 article (11/2021)
2.	Menghoum, N: 1 article (11/2021)
3.	Oriot, P: 1 article (11/2021)
4.	Bayat, Michael: 1 article (11/2013)
5.	Møller, Niels: 1 article (11/2013)

Related Diseases

1.	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 11/11/2013 - "Diabetic ketoacidosis is caused by accumulation of acetoacetic and β-hydroxybutyric acids and is a common acute metabolic complication of type 1 diabetes mellitus. "
2.	Ketosis 04/01/1977 - "Thus, ketosis is viewed as the result of increased mobilization of free fatty acids from adipose tissue (site 1) to the liver (site 2), coupled with simultaneous enhancement of the liver's capacity to convert these substrates into acetoacetic and beta-hydroxybutyric acids. "
3.	Infections 05/12/2023 - "Transmission electron microscopy revealed the following ultrastructural changes in nodules: modifications in the cell walls (their clearing and thinning), thickening of the infection thread walls with the formation of outgrowths, accumulation of poly-β-hydroxybutyrates in bacteroids, expansion of the peribacteroid space, and fusion of symbiosomes. "
4.	Hyperglycemia 11/01/2021 - "Hyperglycemia did not correlate with pH and β-hydroxybutyrates. "
5.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/11/2013 - "Diabetic ketoacidosis is caused by accumulation of acetoacetic and β-hydroxybutyric acids and is a common acute metabolic complication of type 1 diabetes mellitus. "

Related Drugs and Biologics

1.	Sodium
2.	Lithium
3.	Nonesterified Fatty Acids (NEFA)
4.	4-amino-3-phenylbutyric acid (phenibut)
5.	gamma-aminobutyric acid cetyl ester