|1.||Kulkarni, Abhaya V: 24 articles (10/2015 - 11/2007)|
|2.||McAllister, James P: 22 articles (12/2015 - 03/2006)|
|3.||Warf, Benjamin C: 18 articles (04/2015 - 01/2005)|
|4.||Del Bigio, Marc R: 18 articles (01/2014 - 01/2002)|
|5.||Wellons, John C: 14 articles (12/2015 - 02/2002)|
|6.||Drake, James M: 13 articles (01/2015 - 03/2004)|
|7.||Cinalli, Giuseppe: 12 articles (12/2015 - 01/2004)|
|8.||Tubbs, R Shane: 12 articles (12/2015 - 02/2002)|
|9.||Constantini, Shlomi: 12 articles (06/2015 - 02/2002)|
|10.||McGirt, Matthew J: 12 articles (03/2015 - 05/2003)|
02/01/2013 - "The combination of ETV and choroid plexus cauterization (ETV/CPC) has improved the success rate among infants with hydrocephalus for whom ETV alone is much less successful. "
09/01/2014 - "Endoscopic CPC with or without ETV can be a safe and effective treatment alternative to shunt placement in infantile hydrocephalus. "
05/01/2015 - "The authors sought to investigate the efficacy of combining ETV and CPC (ETV+CPC) in treating childhood hydrocephalus in Nigeria. "
06/01/2013 - "This study is the first to report long-term success of ETV +/- choroid plexus cauterization (CPC) for infants with congenital idiopathic hydrocephalus (CIH). "
01/01/2013 - "This study aims to review the role of choroid plexus coagulation (CPC) for hydrocephalus not due to CSF overproduction. "
04/01/2012 - "We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. "
11/01/2014 - "Patients with subarachnoid NCC (SANCC) require months of treatment with both an antiparasitic agent and steroids to avoid complications such as hydrocephalus and vascular events during treatment. "
07/01/2011 - "However, steroids resulted in rapid disappearance of the hydrocephalus. "
11/01/2006 - "They did not improve and hydrocephalus was complicated in August, though he was treated by steroids. "
11/01/1998 - "Also, all the patients received adjuvant treatment with steroids early in the course of treatment, and 140 of 172 cases with hydrocephalus had surgical intervention. "
|3.||Acetazolamide (Diamox)FDA LinkGeneric
01/01/2012 - "Acetazolamide (AZA), used in treatment of early or infantile hydrocephalus, is effective in some cases, while its effect on the choroid plexus (CP) remains ill-defined. "
06/01/1980 - "Acetazolamide-induced improvement in hydrocephalus."
06/01/2015 - "50 Years Ago in The Journal of Pediatrics: Treatment of Hydrocephalus with Acetazolamide: Results in 15 Cases."
01/01/2015 - "Acetazolamide (10 mg/kg TID) showed no effects on clinical signs or ventricular volume in dogs with internal hydrocephalus. "
01/01/2015 - "Acetazolamide is recommended for the reduction of cerebrospinal fluid production in canine internal hydrocephalus. "
09/01/2001 - "Axonal damage associated with enlargement of ventricles during hydrocephalus: a silver impregnation study."
01/01/2008 - "The purpose of this pilot study was to address the efficacy of silver-impregnated EVD catheters in neurological and neurosurgical patients requiring external CSF drainage due to acute occlusive hydrocephalus. "
01/01/2008 - "Efficacy of silver nanoparticles-impregnated external ventricular drain catheters in patients with acute occlusive hydrocephalus."
04/01/2010 - "The aim of this analysis was to compare the efficacy of silver-bearing EVD catheters for reducing the incidence of infection with standard nonimpregnated EVD catheters in neurosurgical patients with acute hydrocephalus. "
09/01/2001 - "Neural damage, as visualized by silver staining, was examined in adult rats 2-10 weeks after obstructive hydrocephalus was induced by kaolin injection into the cisterna magna. "
01/01/2015 - "Endoscopic procedure is less invasive and more effective for biopsy of neurosarcoidosis with hydrocephalus, even if the lesion is located at the fourth ventricle outlet."
07/01/1989 - "Hydrocephalus associated with neurosarcoidosis may progress despite steroid treatment, even when symptoms have improved. "
01/01/2015 - "We report a rare case of progressive hydrocephalus associated with neurosarcoidosis mass lesion located at the fourth ventricle outlet and suprasellar region. "
01/01/2015 - "Endoscopic biopsy for the diagnosis of neurosarcoidosis at the fourth ventricle outlet with hydrocephalus."
12/01/2013 - "CT-scan and MRI showed a temporal-parietal cystic mass, secondary to a rare and focal form of hydrocephalus, called "trapped temporal horn" revealing neurosarcoidosis. "
|6.||Tissue Plasminogen Activator (Alteplase)FDA Link
07/01/1996 - "Phase I study to evaluate intraventricular fibrinolytic treatment with recombinant tissue plasminogen activator (tPA) as a method of clearing blood from the cerebrospinal fluid, and thus preventing permanent hydrocephalus. "
07/01/1996 - "Phase I study of intraventricular recombinant tissue plasminogen activator for treatment of posthaemorrhagic hydrocephalus."
10/01/2003 - "We treated three newborn infants (one term, two preterm) with posthemorrhagic hydrocephalus using recombinant tissue plasminogen activator, a thrombolytic agent, injected into the ventricles with a spinal needle. "
04/01/2003 - "Recombinant tissue plasminogen activator is effective in resolving IVH causing obstructive hydrocephalus and uncontrollable ICP posing a life-threatening situation, secondary to ruptured arteriovenous malformation, before surgical intervention."
10/01/1998 - "With obstructive hydrocephalus secondary to acute traumatic IVH that cannot be controlled with EVD because of recurrent obstruction from intraventricular blood, intraventricular recombinant-tissue plasminogen activator can be effective and safe, despite preexisting multiple hemorrhagic intracranial injuries."
|7.||Minocycline (Cyclops)FDA LinkGeneric
01/01/2010 - "Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus."
01/01/2010 - "Overall, these data suggest that minocycline treatment is effective in reducing the gliosis that accompanies hydrocephalus, and thus may provide an added benefit when used as a supplement to ventricular shunting."
01/01/2012 - "Minocycline treatment is effective in reducing the gliosis and delaying the development of hydrocephalus with prospective to be the auxiliary therapeutic method of hydrocephalus."
01/01/2010 - "The purpose of this study was to determine the efficacy of minocycline, an antibiotic known for its anti-inflammatory properties, to reduce gliosis in the H-Tx rat model of congenital hydrocephalus. "
01/01/2012 - "Our aim is to determine the efficacy of minocycline, an antibiotic known for its anti-inflammatory properties, to reduce reactive gliosis and inhibit the development of hydrocephalus. "
01/01/2015 - "A brain silicone replica mimicking normal mechanical properties of a 4-month-old child with hydrocephalus was constructed, encased in the replicated skull, and immersed in water. "
03/16/2010 - "Occlusion or blockage of silicone shunts utilized in the treatment of hydrocephalus is a major challenge that is currently addressed by multiple shunt replacements. "
01/01/2010 - "Use of silicone to manufacture hydrocephalus shunts has been critical for the successful introduction of modern shunt therapy. "
03/01/2006 - "Silicone shunts coated with SAMs may be suitable for future clinical applications to improve the treatment of hydrocephalus."
11/01/1998 - "Hydrocephalus was induced in adult rabbits by injection of silicone oil into the cisterna magna. "
|9.||Furosemide (Lasix)FDA LinkGeneric
05/16/2007 - "From the medical point of view, treatment with pharmacological agents such as azetazolamide or furosemide offers more drawbacks than advantages as far as their capacity to prevent hydrocephalus is concerned. "
07/01/2001 - "Furosemide was found to be effective in management of bronchoconstriction accompanying chronic lung disease and narrowing of the upper respiratory airways; in hydrocephalus in infancy to avoid cerebrospinal fluid shunts; in some diagnostic procedures, such as an assessment of fetal and neonatal hydronephrosis; and in evaluation of different types of renal tubular acidosis. "
03/01/1999 - "The authors evaluated the efficacy of acetazolamide (ACZ) and furosemide (FUR) in avoiding ventricular shunting procedures in preterm infants with posthemorrhagic hydrocephalus (PHH) and increased intracranial pressure (ICP). "
01/01/2003 - "Conservative treatment with acetazolamide and furosemide does not seem to confer any advantage to the management of posthemorragic hydrocephalus. "
01/01/2001 - "Acetazolamide and furosemide cannot be recommended as therapy for post hemorrhagic hydrocephalus."
|10.||Cefotaxime (Kendrick)FDA LinkGeneric
11/01/1998 - "In spite of rapid clearance of the organism from the cerebrospinal fluid with intravenous cefotaxime, fever persisted over 8 days of therapy and infection was complicated by hydrocephalus. "
01/12/1980 - "Nine children were cured; in one case infection (with a different organism) recurred but a further course of cefotaxime was successful; one child died, with sterile CSF; one child died from his underlying disease (astrocytoma); and one child was cured with sequelae (hydrocephalus). "
01/01/1985 - "Staphylococcus aureus and Staphylococcus epidermidis meningitis, usually secondary in shunted hydrocephalus, brain tumors, brain injury or other causes, should not be treated with cefotaxime because of its limited activity on these bacteria. "
11/08/2002 - "The developed SPE-HPLC method was applied for cefotaxime and desacetylcefotaxime determination in cerebrospinal fluid of children with hydrocephalus after intraventricular administration."
07/01/1993 - "Patients who had undergone external ventriculostomies for noninflammatory occlusive hydrocephalus received either cefotaxime (2 g/30 min) or ceftriaxone (2 g/30 min) to treat extracerebral infections. "
04/01/2009 - "Uncertainty persists on the best treatment for patients with obstructive hydrocephalus: endoscopic third ventriculostomy (ETV) or shunt, particularly in the younger age groups. "
12/01/2008 - "Endoscopic third ventriculostomy: the best option in the treatment of persistent hydrocephalus after posterior cranial fossa tumour removal?"
01/01/2014 - "Endoscopic third ventriculostomy (ETV) is considered the gold standard treatment for obstructive hydrocephalus due to partial or complete obstruction of cerebrospinal fluid (CSF) ventricular pathways caused by mass lesions. "
09/01/2014 - "Endoscopic third ventriculostomy (ETV) is an accepted modality of treatment for obstructive hydrocephalus, with good results in adult patients. "
04/01/2010 - "The authors report on 3 consecutive cases involving infants under the age of 6 months treated successfully with ventriculocystostomy in combination with direct hydrocephalus treatment (endoscopic third ventriculostomy or shunt placement). "
08/01/2004 - "However, the optimal post-operative resistance for different hydrocephalus types is unknown, and randomised clinical trials are needed to confirm improved outcome and reduced complication rate for the Sinushunt compared with traditional low resistance ventriculoperitoneal shunts. "
01/01/1978 - "A CT scan and vertebral angiogram demonstrated an ectatic basilar artery obstructing the posterior third ventricle; the resulting hydrocephalus was relieved by a ventriculo-peritoneal shunt and the patient's symptoms resolved completely."
01/01/2011 - "In the nine cases of concurrent hydrocephalus, this was gradually relieved in eight patients and the single case that became aggravated was successfully treated with ventriculoperitoneal shunt. "
12/01/1981 - "Ventriculoperitoneal shunts showed good results in the treatment of hydrocephalus in 89.4% of the cases in the immediate post-operative time and this number drop to 88.2% at the eighteen post-operative month. "
09/01/2012 - "The ventriculoperitoneal shunt is the mainstay of treatment for hydrocephalus. "
03/01/2005 - "We developed an alternative to valvular shunts based on a simple shunt procedure whose functioning depends on a peritoneal catheter with a highly precise cross-sectional internal diameter of 0.51 mm. Preliminary studies have shown that the shunt of continuous flow (SCF) is superior to valvular shunts for the treatment of hydrocephalus in adults. "
12/01/2013 - "No significant improvement in the rate of accurate ventricular catheter location using ultrasound-guided CSF shunt insertion: a prospective, controlled study by the Hydrocephalus Clinical Research Network."
12/01/2015 - "3) Treatment of Hydrocephalus-improved bioengineering efforts to reduce proximal catheter and overall shunt failure; external or implantable diagnostics and support for the biological infrastructure research that informs these efforts; and evidence-based surgical standardization with longitudinal metrics to validate or refute implemented practices, procedures, or tests. "
10/01/2010 - "Although prospective randomized cost-utility studies are needed to confirm these observations, these results suggest that AIS catheters are cost-effective in the treatment of hydrocephalus in adult patients."
04/01/1986 - "We conclude that ventricular catheter reservoir is a safe and effective palliative procedure in the management of post hemorrhagic hydrocephalus in small preterm infants."
04/01/1994 - "The leptomeningeal enhancement resolved completely after decompression of the hydrocephalus. "
12/01/2006 - "In transient absorptive hydrocephalus, temporary measures were effective in many cases leading to successful procedures of ETV and/or posterior-fossa decompression in selected cases. "
10/01/2002 - "A case of Chiari I malformation is reported, in which foramen magnum decompression was followed by delayed onset of acute hydrocephalus after a week. "
01/01/1991 - "Posterior fossa decompression resulted in improvement in neurologic function and relief of hydrocephalus."
01/01/2001 - "Few reports have documented signal abnormalities within the corpus callosum on MR studies obtained after ventricular decompression in patients with hydrocephalus. "
03/01/2013 - "Preoperative (long-term corticosteroid therapy, previous surgery and radiotherapy), intraoperative (site of procedures and size of dural gap), and postoperative (early and late hydrocephalus) conditions were analyzed as possible risk factors associated with CSF leakage. "
04/01/2012 - "Hydrocephalus and radiotherapy."
07/15/2011 - "Eight patients (11%) developed hydrocephalus within 19 months of radiotherapy, which was successfully treated. "
07/01/2004 - "The rate of IQ decline is associated with a several risk factors, including younger age at time of treatment, longer time since treatment, female sex, as well as clinical variables such as hydrocephalus, use of radiotherapy and radiotherapy dose, and the volume of the brain that received treatment. "
11/01/1999 - "Intracranial lesions may affect hypothalamic-pituitary (HP) function and growth in several ways, depending on the location of the lesion within this area, the presence or absence of secondary hydrocephalus, and/or treatment of the lesion by surgery and/or radiotherapy. "