Polyhydramnios

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319 relevant articles (10 outcomes, 11 trials/studies) found for this Disease

Description: A condition of abnormally high AMNIOTIC FLUID volume, such as greater than 2,000 ml in the LAST TRIMESTER and usually diagnosed by ultrasonographic criteria (AMNIOTIC FLUID INDEX). It is associated with maternal DIABETES MELLITUS; MULTIPLE PREGNANCY; CHROMOSOMAL DISORDERS; and congenital abnormalities.

Also Known As:

Hydramnios

Relationship Network

Disease Context: Research Results

Female Urogenital Diseases and Pregnancy Complications

Pregnancy Complications: 552

Polyhydramnios: 319

Related Diseases

1.	Fetofetal Transfusion (Twin Transfusion Syndrome)
2.	Hydrops Fetalis (Fetal Edema)
3.	Placenta Previa
4.	Oligohydramnios
5.	Premature Obstetric Labor (Premature Labor)

Experts

1.	Taylor, Robert N: 2 articles (03/2006 - 06/2005)
2.	Mann, Stephanie E: 2 articles (03/2006 - 06/2005)
3.	Ward, Stuart: 2 articles (03/2004 - 07/2003)
4.	Bajoria, Rekha: 2 articles (03/2004 - 07/2003)
5.	Jayagopal, N: 1 article (11/2007)
6.	Sinha, D: 1 article (11/2007)
7.	Bhatti, N R: 1 article (11/2007)
8.	Gilbert, Heather: 1 article (03/2006)
9.	Dvorak, Natalia: 1 article (03/2006)
10.	Torres, Elvina A: 1 article (06/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Polyhydramnios:

1.	Indomethacin (Indometacin)FDA LinkGeneric 07/01/2000 - "CONCLUSION: Indomethacin was effective in the management of hydramnios and preventing it's complications." 05/01/1996 - "However, although indomethacin appears to be effective in the treatment of polyhydramnios, our goal is to analyze efficacy and side effects, so as to define conditions of clinical use." 10/01/1992 - "Inhibition of prostaglandin synthesis with indomethacin has been reported to be effective for prevention of labor and for treatment for symptomatic polyhydramnios. " 06/01/1992 - "After sonographic evaluation has confirmed the polyhydramnios and a determination is made of the potential etiologies, indomethacin appears to be an effective agent in reducing the amniotic fluid volume and in preventing prematurity." 11/28/1992 - "In comparative trials of indomethacin as short treatment of premature labour and polyhydramnios the drug proved to be effective. " Order ALL the reference details at left...
2.	Carbon MonoxideIBA 09/01/1992 - "Five pregnancies initially diagnosed as having a 'stuck' twin showed improvement in amniotic fluid volume, with one actually reversing, so that the previously 'stuck' twin developed polyhydramnios and the co-twin became 'stuck'. " 10/01/1999 - "Polyhydramnios of the co-twin was found in 80% of TTTS cases, while no polyhydramnios was found in patients without TTTS (p < 0.05). " 05/01/1999 - "Excessive volumes of amniotic fluid (polyhydramnios) were observed in 23% of conceptuses derived from co-cultured embryos. " 01/01/1987 - "The hydramnios resolved and the surviving co-twin was delivered at term." 01/01/2003 - "Multifetal gestations are high-risk pregnancies involving higher perinatal morbidity and mortality, and are subject to unique complications including twin oligohydramnios-polyhydramnios sequence, twin-to-twin transfusion syndrome, acardiac twins, conjoined twins, co-twin demise, and heterotopic pregnancies. " Order ALL the reference details at left...
3.	Ethanol (Ethyl Alcohol)IBA 01/01/2007 - "Successful intratumoral injection of absolute ethyl alcohol relieved hydrops fetalis and polyhydramnios. " 02/01/2004 - "Rapid growth of the acardiac sibling, high diastolic velocity Doppler waveforms in the perfusing vessel, and early hydramnios prompted ablation of blood flow by a percutaneous ultrasonographically guided infusion of absolute alcohol. " Order ALL the reference details at left...
4.	Direction compoundIBA 03/01/2001 - "In conclusion, reversal of the normal direction of net foeto-foetal transfusion, induced by polyhydramnios, is protective against the onset and severity of twin-twin transfusion syndrome in monochorionic twins connected by arterio-venous plus arterio-arterial anastomoses, but not by unidirectional or bidirectional arterio-venous anastomoses." Order ALL the reference details at left...
5.	alpha-Fetoproteins (AFP)IBA 06/18/1998 - "Rarer causes of malpractice problems relate to failure to communicate the results of a sonogram in a timely fashion, failure to inform the patient of the findings about the sonogram at the time the patient is seen, and failure to perform ultrasound studies for anomalies when there is clinical indication to do so, such as elevated alpha-fetoprotein or polyhydramnios. " 05/01/2009 - "Our review confirmed the reported association with increased AFP and hydramnios. " 05/01/2009 - "They have been associated with increased alpha-fetoprotein (AFP), hydramnios, congenital anomalies, and increased perinatal mortality. " 02/01/2002 - "The pregnancy was complicated by severe polyhydramnios and elevated amniotic fluid alpha-fetoprotein (AFP). " 01/01/1986 - "When polyhydramnios was the sole anomaly (25 cases), 5 fetuses were malformed (20%), abnormal fetal karyotype and/or elevated amniotic fluid alphafetoprotein (AFP) were demonstrated in 2 cases. " Order ALL the reference details at left...
6.	ProlactinIBA 01/01/2007 - "As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios." 04/01/2000 - "Acute recurrent polyhydramnios and amniotic prolactin." 03/01/1984 - "The present data suggest that 1) maternal and fetal prolactin levels do not differ significantly between normal and abnormal pregnancies, 2) the decidua is the principal source of amniotic fluid prolactin, and 3) the significantly lower levels of prolactin in amniotic fluid of pregnancies complicated by hypertension or polyhydramnios are probably due to adverse effects of these conditions on the synthesis and release of prolactin by decidua." 03/01/1984 - "Prolactin levels in amniotic fluid as well as decidual prolactin content and production were significantly lower only in pregnancies complicated by either hypertension or polyhydramnios. " 03/01/1984 - "In the present studies, the content and the in vitro production of prolactin by decidua as well as the concentrations of prolactin in amniotic fluid, maternal and fetal serum in normal term pregnancies, induced abortions at various gestational ages, and in pregnancies complicated by diabetes mellitus, preeclampsia, chronic hypertension, and polyhydramnios were measured. " Order ALL the reference details at left...
7.	TOPSIBA 09/01/2002 - "OBJECTIVE: The purpose of this study was to review consecutive pregnancies complicated by twin oligohydramnios-polyhydramnios sequence (TOPS) and to clarify the probable factors influencing the perinatal outcomes. " 06/01/2008 - "Antenatal sonographic diagnosis of twin-twin transfusion syndrome (TTTS) is based on findings of a twin oligo-polyhydramnios sequence (TOPS) observed in monochorionic twin fetuses. " 03/01/1998 - "OBJECTIVE: To report our experience with intentional puncture of the intervening membrane ('septostomy') for the treatment of the twin oligohydramnios-polyhydramnios sequence (TOPS). " 03/01/1999 - "OBJECTIVE: To measure acute and chronic changes in the placenta and amniotic fluid associated with performance of decompression amniocentesis in pregnancies with the twin oligohydramnios-polyhydramnios sequence (TOPS). " 01/01/2007 - "We report an uncommon form of chronic inter-twin transfusion, referred to as twin anemia-polycythemia sequence (TAPS), with severe anemia in one twin and polycythemia in the other, without the characteristically associated twin oligo-polyhydramnios sequence (TOPS) seen in the classical twin-to-twin transfusion syndrome (TTTS). " Order ALL the reference details at left...
8.	Matrix MetalloproteinasesIBA 01/01/2004 - "The concentrations of these MMPs were significantly elevated in the polyhydramnios samples independent of gestational age. " 01/01/2004 - "Herein we use polyhydramnios as a model to study the association of the collagenase class of matrix metalloproteinases (MMPs) with tissue remodeling during pregnancy. " Order ALL the reference details at left...
9.	Collagenases (Collagenase)FDA Link 01/01/2004 - "Herein we use polyhydramnios as a model to study the association of the collagenase class of matrix metalloproteinases (MMPs) with tissue remodeling during pregnancy. " Order ALL the reference details at left...
10.	Immunoglobulin M (IgM)IBA 09/01/2000 - "Included in the study group were women with IUGR, PROM, preterm delivery imminent, Toxoplasmosis in previous pregnancies, raised IgG or IgM anti-Toxoplasma antibody titers and with amniotic fluid disturbances (oligohydramnios and polyhydramnios). " Order ALL the reference details at left...

Therapies and Procedures

1.	Decompression 09/01/1992 - "Amniotic fluid decompression was performed for symptomatic polyhydramnios complicating four sets of discordant twin gestations. " 09/01/1992 - "Reduction in the middle cerebral artery pulsatility index after decompression of polyhydramnios in twin gestation." 01/01/1988 - "Reversal of acute polyhydramnios after fetal renal decompression." 03/01/1999 - "Equalization of amniotic fluid volumes after decompression amniocentesis for treatment of the twin oligohydramnios-polyhydramnios sequence." 01/01/1988 - "Antenatal fetal cyst decompression successfully reversed the polyhydramnios and prevented premature delivery, resulting in a full-term healthy infant delivered vaginally at thirty-nine weeks. " Order ALL the reference details at left...
2.	Renal Dialysis (Hemodialysis) 07/01/2002 - "Polyhydramnios occurred in 6 of 9 surviving live births and was partially relieved after hemodialysis. " 09/01/1988 - "Polyhydramnios appears to be a major complication in women dependent upon chronic hemodialysis." 07/01/1990 - "We report a case of successfully managed pregnancy complicated by maternal chronic renal failure requiring hemodialysis, severe intrauterine growth retardation and polyhydramnios. " 07/01/2008 - "Pregnancy in women on hemodialysis is very uncommon, and rates of spontaneous abortion, hypertension, pre-eclampsia, polyhydramnios, pre-term labor, and premature birth are high. " Order ALL the reference details at left...
3.	Cervical Cerclage 01/01/2006 - "Exclusion criteria were: previous preterm delivery, or mid-trimester abortion or termination of pregnancy, multiple gestation, oligo- or polyhydramnios, placenta previa, fetal abnormalities, uterine malformations, cervical incompetence, cervical cerclage, or receipt of an antibiotic effective against BV or GBS following the screening. " Order ALL the reference details at left...
4.	Induced Abortion (Induced Abortions) 01/01/1980 - "In 3 per cent of the cases there was a previous abortion and in 18 per cent it appeared that there was previous hydramnios. " 06/01/1990 - "An analysis of 30,621 consecutive deliveries showed that previous abortion, bleeding during pregnancy, polyhydramnios, oligohydramnios, operative delivery, multiple pregnancy, abnormal placentation, and primary cesarean were each associated with unexpectedly high transfusion rates. " 09/01/1975 - "When the effects of other variables were taken into account, there were no significant changes in frequency following an induced abortion as to: ABO and rhesus isoimmunization, toxemia, hydramnios, premature rupture of membranes, induction of labor, breech or vacuum delivery, cesarean section, breech presentation, placenta previa, placental abruption, cord prolapse, cord anomalies, fetal distress or asphyxia, post-partum hemorrhage." 03/01/1984 - "In the present studies, the content and the in vitro production of prolactin by decidua as well as the concentrations of prolactin in amniotic fluid, maternal and fetal serum in normal term pregnancies, induced abortions at various gestational ages, and in pregnancies complicated by diabetes mellitus, preeclampsia, chronic hypertension, and polyhydramnios were measured. " 08/01/1989 - "Of a total of 12,005 pregnancies (4561 Asian and 7444 White Caucasian), over a 3-year period, 314 (6.8%) Asian and 504 (6.7%) White Caucasian were given a 75-g oral glucose tolerance test (OGTT) at 28-32 weeks for indications of 'large for date' pregnancies, hydramnios, glycosuria, a history of previous abortions, stillbirths, congenital abnormalities or glucose intolerance, and family history of diabetes. " Order ALL the reference details at left...
5.	Ligation 03/01/2000 - "CONCLUSION: Polyhydramnios did not occur after esophageal ligation, even though the fetuses excreted approximately 4000 mL of urine over the 9-day study period. " 07/01/1996 - "The selection criteria prior to offering percutaneous umbilical cord ligation included normal anatomy in the other fetus(es), normal karyotype and polyhydramnios, or uterine contractions. " 08/01/2002 - "CONCLUSION: In this model of gastroschisis in the fetal sheep, ligature of the esophagus, which was supposed to protect the extruded bowel by preventing oral regurgitation of digestive enzymes and by creating a relative hydramnios, did not improve the inflammatory and deleterious process, which is best prevented by amnioinfusion." Order ALL the reference details at left...

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