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Hydatidiform Mole (Molar Pregnancy)

Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
Also Known As:
Molar Pregnancy; Molar Pregnancies; Hydatid Mole; Hydatidiform Mole, Complete; Hydatidiform Mole, Partial; Complete Hydatidiform Mole; Complete Hydatidiform Moles; Hydatid Moles; Hydatidiform Moles; Hydatidiform Moles, Complete; Hydatidiform Moles, Partial; Mole, Complete Hydatidiform; Mole, Hydatid; Mole, Hydatidiform; Mole, Partial Hydatidiform; Moles, Complete Hydatidiform; Moles, Hydatid; Moles, Hydatidiform; Moles, Partial Hydatidiform; Partial Hydatidiform Mole; Partial Hydatidiform Moles; Pregnancies, Molar; Pregnancy, Molar
Networked: 1234 relevant articles (41 outcomes, 128 trials/studies)

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Disease Context: Research Results

Related Diseases

1. Choriocarcinoma
2. Hydatidiform Mole (Molar Pregnancy)
3. Invasive Hydatidiform Mole (Invasive Mole)
4. Trophoblastic Neoplasms (Trophoblastic Tumor)
5. Neoplasms (Cancer)

Experts

1. Berkowitz, Ross S: 12 articles (06/2014 - 05/2002)
2. Cheung, Annie N Y: 12 articles (01/2014 - 07/2003)
3. Ngan, Hextan Y S: 10 articles (06/2012 - 07/2003)
4. Seckl, Michael J: 9 articles (11/2014 - 06/2002)
5. Seckl, M J: 9 articles (05/2013 - 07/2000)
6. Sebire, N J: 9 articles (11/2012 - 12/2001)
7. Thomas, Chris M G: 8 articles (06/2014 - 10/2005)
8. Fisher, R A: 8 articles (05/2013 - 07/2000)
9. Hui, Pei: 7 articles (09/2014 - 03/2008)
10. Murphy, Kathleen M: 7 articles (02/2014 - 09/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hydatidiform Mole:
1. Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
2. DNA (Deoxyribonucleic Acid)IBA
3. Oral ContraceptivesIBA
4. Messenger RNA (mRNA)IBA
5. Dactinomycin (Ac-De)FDA LinkGeneric
6. Gestational trophoblastic diseaseIBA
7. Estrogens (Estrogen)FDA Link
8. HormonesIBA
9. Macrophage Colony-Stimulating FactorIBA
10. Methotrexate (Mexate)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Contraception (Birth Control)
3. Curettage
4. Vacuum Curettage (Vacuum Pump)
5. Intrauterine Devices (Intrauterine Device)
08/01/1986 - "The intrauterine contraceptive device and hydatidiform mole: a negative association."
01/01/2000 - "In a prospective, simple randomised study, we evaluated the relative efficacy of hormonal (oral contraceptive pill) and non-hormonal (intrauterine contraceptive device) methods of contraception as fertility regulatory agents in patients with complete hydatidiform moles and assessed the development of complications and sequelae if any, following their use. "
11/01/1975 - "Certain conditions lend themselves to diagnosis with ultrasound: hydatidiform mole, intrauterine pregnancy, dermoid cyst, ascites, simple ovarian cyst, and lost intrauterine contraceptive devices (IUCD's). "
06/01/1983 - " Discussion focuses on methods, instrumentation, method for examination (grasping the instrument, setup, light source, anesthesia, dilatation, technique, and normal endometrium); cervical neoplasia; nonneoplastic lesions of the endometrium (endometrial polyp, submucous myoma, endometrial hyperplasia); intrauterine device localization; neoplastic lesions of the endometrium; precursors (adenocarcinoma); hysteroscopy in pregnancy (embryoscopy, hydatidiform mole, postpartum hemorrhage, incomplete abortion, spontaneous abortion, induced abortions, and amnioscopy); and examinations of children and infants. "
01/15/1983 - "Relationship of oral contraceptives and the intrauterine contraceptive devices to the regression of concentrations of the beta subunit of human chorionic gonadotropin and invasive complications after molar pregnancy."