Horseradish Peroxidase

An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.

Also Known As:

Alpha-Peroxidase; Ferrihorseradish Peroxidase; Horseradish Peroxidase II; Horseradish Peroxidase III; Alpha Peroxidase; II, Horseradish Peroxidase; III, Horseradish Peroxidase; Peroxidase II, Horseradish; Peroxidase III, Horseradish; Peroxidase, Ferrihorseradish; Peroxidase, Horseradish

Networked: 973 relevant articles (8 outcomes, 82 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Peroxidases: 304
      - Horseradish Peroxidase: 973
        Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate: 55
        IGG-horseradish peroxidase: 6
        concanavalin A-horseradish peroxidase conjugate: 5
        avidin-horseradish peroxidase complex: 2
        B subunit-horseradish peroxidase cholera toxin: 2
        horseradish peroxidase-coupled gold: 2
        horseradish peroxidase-polylysine conjugate: 2
        asialo-orosomucoid-horseradish peroxidase conjugate
        dextran-horseradish peroxidase conjugate
        horseradish apoperoxidase
        magnesium mesoporphyrin horseradish peroxidase
        Nicotiana tabacum TFHP-1 protein
        oxyferryl porphyrin pi cation radical
        progesterone-11HS-horseradish peroxidase
        progesterone-3-(O-carboxymethyl oxime)-horseradish peroxidase
        Strep-avidin conjugated horseradish peroxidase
        transferrin-horseradish peroxidase conjugate
        trinitrophenyl-polylysine-horseradish peroxidase
        Vicia villosa agglutinin-horseradish peroxidase conjugate

Experts

1.	Kim, Dong-Seok: 7 articles (02/2010 - 01/2004)
2.	Park, Kyoung-Chan: 6 articles (09/2009 - 01/2004)
3.	Ju, Huangxian: 5 articles (06/2018 - 10/2003)
4.	Kim, So-Young: 5 articles (09/2009 - 02/2006)
5.	Dachs, G U: 4 articles (06/2010 - 11/2000)
6.	Jeong, Yun-Mi: 4 articles (02/2010 - 02/2006)
7.	Kwon, Sun-Bang: 4 articles (04/2009 - 02/2006)
8.	Jeon, Sang-Eun: 4 articles (12/2006 - 01/2004)
9.	Wardman, Peter: 4 articles (09/2002 - 01/2002)
10.	Spadiut, Oliver: 3 articles (10/2021 - 01/2016)

Related Diseases

1.	Ganglion Cysts (Ganglion) 03/01/1981 - "Retrograde filling with horseradish peroxidase (HRP) from the optic fiber tract helped to validate Nissl criteria and served to identify displaced ganglion cells. " 11/01/1996 - "In this study, ganglion cells of frogs from two species (Bufo marinus, Xenopus laevis) were filled retrogradely with horseradish peroxidase. " 07/22/1990 - "The purpose of the present study was to place horseradish peroxidase on the distal processes of the three ampullary nerves in 6-8-week-old chickens so that we could identify the ganglion cells associated with each nerve and trace the specific central pathways taken by each nerve in the brainstem. " 11/08/1989 - "In the present study, we have explored the morphology of lumbar sympathetic chain ganglion cells by intracellular injection with horseradish peroxidase to determine whether an anatomical substrate exists for processing information within these ganglia. " 12/08/1987 - "Immunocytochemistry and retrograde horseradish peroxidase (HRP) transport were used to study the ganglion of the nervus terminalis in the American eel, Anguilla rostrata. "
2.	Neoplasms (Cancer) 01/01/2023 - "The surface of the synthesized nanocomposites was modified with horseradish peroxidase (HRP) to enhance the deep penetration of the nanocomposites in cancer cells. " 01/01/2020 - "Graphical abstract Schematic representation of the sensing process of immunoassay-type biosensor based on magnetic nanoparticle capture and the fluorescence signal formed by the horseradish peroxidase (HRP) catalysis for tumor-related exosome determination." 01/01/2020 - "Immunoassay-type biosensor based on magnetic nanoparticle capture and the fluorescence signal formed by horseradish peroxidase catalysis for tumor-related exosome determination." 01/01/2016 - "Recombinant horseradish peroxidase variants for targeted cancer treatment." 01/01/1987 - "Intravenously injected horseradish peroxidase (HRP) crossed the tumor blood-brain barrier (BBB) only in those tumors in which contrast enhancement was seen. "
3.	Carcinoma (Carcinomatosis) 10/15/2003 - "Reagentless amperometric immunosensors based on direct electrochemistry of horseradish peroxidase for determination of carcinoma antigen-125." 01/01/2001 - "Induction of reduced endothelial permeability to horseradish peroxidase by factor(s) of human astrocytes and bladder carcinoma cells: detection in multi-well plate culture." 06/01/1988 - "In human larynges, excised for large unilateral carcinoma, horseradish peroxidase (HRP) was injected into the internal branch of the NLS. " 10/01/1979 - "Horseradish peroxidase (HRP) uptake was used to measure fluid-phase pinocytosis in monolayers of human epithelioid carcinoma cells (A-431). " 02/01/2010 - "Indole-3-acetic acid/horseradish peroxidase induces apoptosis in TCCSUP human urinary bladder carcinoma cells."
4.	Urinary Bladder Neoplasms (Bladder Cancer) 07/01/2000 - "Immunohistochemical staining using CD68/horseradish peroxidase monoclonal antibody showed more infiltrating cells in invasive than superficial bladder cancers. " 11/01/1998 - "To eliminate background signals derived from both sources and to benefit from the peroxidase-driven tyramide signal amplification (TSA), we directly conjugated horseradish peroxidase (HRP) to oligodeoxynucleotides (ODNs) and used these probes to study in the bladder cancer cell line 5637 the expression of various cytokine genes which, according to Northern hybridization and reverse transcriptase-polymerase chain reaction (RT-PCR) assays, are expressed at levels up to 10,000-fold less than abundantly expressed housekeeping genes. " 10/01/2021 - "Hyaluronic acid-coated chitosan nanoparticles as carrier for the enzyme/prodrug complex based on horseradish peroxidase/indole-3-acetic acid: Characterization and potential therapeutic for bladder cancer cells."
5.	Endolymphatic Hydrops 06/01/1998 - "This paper reports that endolymphatic hydrops causes a significant reduction of retrogradely labeled cell bodies of the ipsilateral trigeminal ganglion following application of horseradish peroxidase in the cochlea. " 08/01/1990 - "This was followed by a light and electron microscopic study on the changes in permeability of the cochlear lateral wall with horseradish peroxidase and a study of the development mechanism of endolymphatic hydrops. "

Related Drugs and Biologics

1.	Antigens
2.	Enzymes
3.	Lectins
4.	Avidin
5.	Hydrogels
6.	Antibodies
7.	Prodrugs
8.	indole
9.	Acetic Acid (Vinegar)
10.	Hyaluronic Acid (Hyaluronan)

Related Therapies and Procedures

1.	Ligation
2.	Injections
3.	Intravenous Injections
4.	Intravenous Administration
5.	Axotomy