HLA-DQ Antigens (HLA-DQ)

A group of the D-related HLA antigens found to differ from the DR antigens in genetic locus and therefore inheritance. These antigens are polymorphic glycoproteins comprising alpha and beta chains and are found on lymphoid and other cells, often associated with certain diseases.
Also Known As:
HLA-DQ; HLA-DC; HLA-DS; HLA-DS Antigens; HLA-LB; HLA-LB Antigens; HLA-MB; Antigens, HLA-DC; Antigens, HLA-DQ; Antigens, HLA-DS; Antigens, HLA-LB; Antigens, HLA-MB; HLA DC Antigens; HLA DQ Antigens; HLA DS Antigens; HLA LB Antigens; HLA MB Antigens; HLA-DC Antigens; HLA-MB Antigens
Networked: 648 relevant articles (9 outcomes, 75 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Sollid, Ludvig M: 6 articles (02/2015 - 04/2003)
2. Shen, Hongbing: 5 articles (01/2015 - 05/2012)
3. Hu, Zhibin: 5 articles (01/2015 - 05/2012)
4. David, Chella S: 5 articles (01/2010 - 01/2002)
5. Mulder, Chris J J: 5 articles (04/2008 - 03/2006)
6. Badenhoop, Klaus: 5 articles (11/2007 - 06/2002)
7. Partanen, J: 5 articles (01/2005 - 12/2000)
8. Zanelli, E: 5 articles (06/2002 - 04/2000)
9. David, C S: 5 articles (11/2001 - 03/2000)
10. Liu, Jibin: 4 articles (01/2015 - 05/2012)

Related Diseases

1. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/15/2000 - "Studies of the stability of HLA-DQ have revealed a correlation between SDS stability of MHC class II alphabeta dimers and insulin-dependent diabetes mellitus (IDDM) susceptibility. "
02/01/1995 - "Analysis of HLA-DQ molecules in a large study comprising 425 consecutively diagnosed Swedish Caucasians with IDDM and 367 age, sex and geographically matched controls confirms previous observations that: (a) DQB1*0302-DQA1*0301 confer susceptibility in a dominant manner, except when they are associated with DQB1*0602-DQA1*0102; (b) DQB1*0501-DQA1*0201 does not confer susceptibility to IDDM in either homozygous or heterozygous combinations with any other DQ molecules except when it is in association with DQB1*0302-DQA1*0301; (c) heterozygous combinations of DQB1*0302-DQA1*0301 and DQB1*0501-DQA1*0201 confer the highest risk to IDDM; (d) in DQ2 positive patients being negative for DQ8 in second haplotype (n = 58) the susceptibility may be explained by DR, since all these patients were DR3 positive, or by unknown factors between DQ and DR and (e) DQB1*0602-DQA1*0102 confers protection in a dominant manner. "
09/01/1994 - "A rapid method to study the relationship between IDDM and HLA-DQ beta 57 Asp."
06/28/1990 - "The availability of a large group of patients with IDDM enabled us to assess the role of HLA-DQ alleles in susceptibility to the disease in order to confirm and extend recent observations derived from studies of smaller numbers of patients. "
06/01/1990 - "HLA-DQ beta-chain restriction fragment length polymorphism as a risk marker in type 1 (insulin-dependent) diabetes mellitus: a Finnish family study."
2. Infection
3. Rheumatoid Arthritis
4. Spontaneous Abortion (Miscarriage)
5. Liver Diseases (Liver Disease)

Related Drugs and Biologics

1. Aspartic Acid (Aspartate)
2. HLA-DRB1 antigen (HLA DRB1)
3. HLA-DR Antigens (HLA-DR)
4. HLA-DP Antigens (HLA-DP)
5. Insulin (Novolin)
6. Histocompatibility Antigens Class II
7. Amino Acids
8. HLA-C Antigens (HLA-C)
9. Antigens
10. Genetic Markers (Genetic Marker)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Surgical Instruments (Clip)
3. Transplants (Transplant)
4. Aftercare (After-Treatment)
5. Stem Cell Transplantation