|1.||Esteller, Manel: 38 articles (09/2015 - 12/2003)|
|2.||Rahman, Irfan: 20 articles (02/2014 - 05/2002)|
|3.||Garcia, Benjamin A: 18 articles (12/2015 - 11/2005)|
|4.||Barnes, Peter J: 16 articles (02/2014 - 01/2004)|
|5.||Dashwood, Roderick H: 16 articles (06/2013 - 08/2004)|
|6.||Marquez, Victor E: 16 articles (04/2013 - 01/2009)|
|7.||Akbarian, Schahram: 15 articles (10/2015 - 08/2005)|
|8.||Allis, C David: 15 articles (06/2015 - 04/2003)|
|9.||Hoffman, Robert M: 15 articles (05/2015 - 06/2004)|
|10.||El-Osta, Assam: 15 articles (01/2015 - 09/2004)|
06/20/2014 - "Bizine was found to be effective at modulating bulk histone methylation in cancer cells, and ChIP-seq experiments revealed a statistically significant overlap in the H3K4 methylation pattern of genes affected by bizine and those altered in LSD1-/- cells. "
02/15/2006 - "Treatment with Eg5 ASO produced a statistically significant reduction of tumor growth, reduction in Eg5 expression in the tumors, and changes in histone phosphorylation, consistent with a loss of Eg5 protein expression. "
09/01/2003 - "Histone H1 treatment significantly inhibited tumor growth, enhanced mean survival time and significantly improved the immune response and status. "
08/25/2005 - "(S)-11 at concentrations as low as 0.1 microM was effective in causing histone hyperacetylation and p21(WAF/CIP1) overexpression and suppressing proliferation in cancer cells."
09/01/2013 - "Preoperative detection of modified forms of histone H4 expression in tumor biopsies would be helpful in management of patients with HCC."
02/26/2008 - "Genetic immunization of BALB/c mice with the individual histones only resulted in a delay in lesion development, whereas the immunization with any one of the plasmids encoding a pair of histones provided stronger, though still partial protection against Leishmania major infection compared to the combination of the four histones. "
10/20/2015 - "T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX."
01/01/2012 - "Experiments on Drosophila have shown that the histones that are normally bound to lipid droplets inside cells can be released to provide protection against infection."
01/01/2009 - "Since ASF1 mediates eviction and deposition of histones during transcription, the interaction of VZV IE63 with ASF1 may help to regulate transcription of viral or cellular genes during lytic and/or latent infection."
08/01/2015 - "The present work studies the consequences of HCV-induced histone modifications in early stages of infection. "
06/01/2012 - "Immunohistochemical studies evaluated cell proliferation (histone H3 and Ki-67), microvessel density (CD31), and inflammation (CD45 and CD68). "
04/15/2011 - "Clinical studies demonstrated markedly increased global acetylation of histone 3 in the inflamed tissue of patients with allergic inflammation. "
01/01/2016 - "However, whether the mechanism by which TSA inhibits inflammation is through significantly enhancing histone acetylation, in order to selectively suppress the expression of proinflammatory genes, and/or through regulating non‑histone acetylation requires further research. "
12/15/2015 - "JMJD2B gene knockdown confirmed a critical role for this histone demethylase in mediating PCB-induced inflammation of the vascular endothelium. "
12/01/2015 - "Thus we conclude that histone acetylation contributes to the regulation of NR4A1 expression in hypercholesterolaemia, and that NR4A1 expression reduces hypercholesterolaemia-induced inflammation. "
01/01/2014 - "Our results suggest that the host-protective effects of PTX3 in sepsis are a result of its coaggregation with histones rather than its ability to mediate pattern recognition. "
05/01/2015 - "The purpose of this study was to define the relationship in polymicrobial sepsis (in adult male C57BL/6 mice) between heart dysfunction and the appearance in plasma of extracellular histones. "
10/01/2015 - "To investigate the impact of circulating histones on cardiac injury and dysfunction in a murine model and patients with sepsis. "
10/01/2015 - "Circulating Histones Are Major Mediators of Cardiac Injury in Patients With Sepsis."
09/01/2015 - "Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients."
06/01/1996 - "They responded well to the corticosteroid therapy, with a cytotoxic agent in one case, and the titers of anti-(histone-DNA) antibody was decreased along with the improvement of proteinuria. "
12/01/1992 - "Western blot analysis revealed antibodies to histone subfractions in sera of 33/34 lupus mice that developed proteinuria. "
04/15/1998 - "Of the BWgammaR(+/+) and +/- mice, 50% showed immune complex glomerulonephritis with heavy proteinuria at 8 mo of age, while only 10% of the BWgammaR(-/-) mice were affected at 14 mo. The serum concentration of anti-dsDNA and anti-histone Abs was dramatically reduced in BWgammaR(-/-) mice. "
02/01/2012 - "Laboratory tests showed anemia with leucopenia, hypocomplementemia, proteinuria, ANA positive at 1:320, and antibodies against dsDNA, Ro/SSA, La/SSB and histone. "
11/01/1994 - "While the level of antibodies to dsDNA, histones and core particles decreased significantly before the appearance of proteinuria, suggesting their involvement in glomerular injury, the longitudinal pattern of anti-U-H2A peptide response was apparently not linked to the manifestation of lupus nephritis in GVHD mice."
|1.||DNA (Deoxyribonucleic Acid)
|5.||Histone Deacetylase Inhibitors
|6.||Antigen-Antibody Complex (Immune Complex)
|8.||Proteins (Proteins, Gene)
|10.||Messenger RNA (mRNA)
|3.||Transplantation (Transplant Recipients)
|5.||Heterologous Transplantation (Xenotransplantation)