HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Histone Deacetylases (Histone Deacetylase)

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
Also Known As:
Histone Deacetylase; Class I Histone Deacetylases; Class II Histone Deacetylases; HDAC Proteins; Histone Deacetylase Complexes; Complexes, Histone Deacetylase; Deacetylase Complexes, Histone; Deacetylase, Histone; Deacetylases, Histone
Networked: 2514 relevant articles (80 outcomes, 265 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Atadja, Peter: 21 articles (02/2014 - 08/2003)
2. McKinsey, Timothy A: 20 articles (03/2015 - 08/2002)
3. Olson, Eric N: 18 articles (03/2014 - 08/2002)
4. Grant, Steven: 16 articles (06/2013 - 07/2003)
5. Dashwood, Roderick H: 16 articles (09/2012 - 02/2006)
6. Chen, Ching-Shih: 13 articles (01/2015 - 08/2005)
7. Alam, Hasan B: 12 articles (01/2016 - 03/2006)
8. Ho, Emily: 12 articles (12/2015 - 03/2006)
9. Kim, Hyung Sik: 11 articles (09/2015 - 09/2007)
10. Barnes, Peter J: 11 articles (03/2013 - 01/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Neurodegenerative Diseases (Neurodegenerative Disease)
3. Breast Neoplasms (Breast Cancer)
4. Huntington Disease (Huntington's Disease)
5. Colonic Neoplasms (Colon Cancer)

Related Drugs and Biologics

1. Histone Deacetylase Inhibitors
2. DNA (Deoxyribonucleic Acid)
3. vorinostat (suberoylanilide hydroxamic acid)
4. Valproic Acid (Valproate, Semisodium)
5. Enzymes
6. trichostatin A (A 300)
7. Proteasome Endopeptidase Complex (Proteasome)
8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9. LBH589
10. Histones (Histone)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Ligation
4. Heterologous Transplantation (Xenotransplantation)
5. Aftercare (After-Treatment)