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Histamine H2 Antagonists

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Also Known As:
Antagonists, Histamine H2; Blockaders, Histamine H2 Receptor; H2 Receptor Blockaders; Histamine H2 Blockers; Receptor Antagonists, Histamine H2; Receptor Blockaders, H2; Blockaders, H2 Receptor; Blockers, Histamine H2; H2 Antagonists, Histamine; H2 Antihistaminics; H2 Blockers, Histamine; Antihistaminics, H2; Histamine H2 Receptor Antagonists; Histamine H2 Receptor Blockaders
Networked: 103 relevant articles (7 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Delaney, B: 3 articles (01/2004 - 01/2000)
2. Innes, M: 3 articles (01/2004 - 01/2000)
3. Deeks, J: 3 articles (01/2004 - 01/2000)
4. Moayyedi, P: 3 articles (01/2004 - 01/2000)
5. Soo, S: 3 articles (01/2004 - 01/2000)
6. Forman, D: 3 articles (01/2004 - 01/2000)
7. Kinoshita, Yoshikazu: 2 articles (02/2005 - 03/2003)
8. Adachi, Kyoichi: 2 articles (02/2005 - 03/2003)
9. Baird, Drew C: 1 article (10/2015)
10. Karmes, Aaron S: 1 article (10/2015)

Related Diseases

1. Duodenal Ulcer (Curling's Ulcer)
2. Hemorrhage
3. Esophagitis
4. Ulcer
5. Dyspepsia (Indigestion)

Related Drugs and Biologics

1. Proton Pump Inhibitors
2. Cimetidine (Biomet)
3. Antacids
4. Omeprazole (Esomeprazole)
5. Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
6. Misoprostol (Cytotec)
7. Sucralfate (Carafate)
8. Bethanechol (Duvoid)
9. Prostaglandins E (PGE)
10. Pepsin A (Pepsin)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Intensive Care (Surgical Intensive Care)
3. Combination Drug Therapy (Combination Chemotherapy)
4. Aftercare (After-Treatment)