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Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Also Known As:
Antagonists, Histamine H1; Antagonists, Histamine H1 Receptor; Antihistamines, Sedating; Blockaders, Histamine H1 Receptor; First Generation H1 Antagonists; H1 Receptor Blockaders; Histamine H1 Blockers; Receptor Blockaders, H1; Classical Antihistamines; Classical Antihistaminics; H1 Antagonists, Histamine; H1 Antihistaminics; Sedating Antihistamines; Antihistamines, Classical; Antihistaminics, Classical; Antihistaminics, H1; Histamine H1 Receptor Antagonists; Histamine H1 Receptor Blockaders
Networked: 105 relevant articles (15 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Maurer, M: 3 articles (09/2010 - 07/2009)
2. Yanai, Kazuhiko: 2 articles (12/2013 - 11/2003)
3. Metz, M: 2 articles (09/2010 - 07/2009)
4. Kamei, Chiaki: 2 articles (01/2010 - 03/2007)
5. Bonilla-Lopez, Sonia: 1 article (12/2015)
6. Tlacuilo-Parra, Alberto: 1 article (12/2015)
7. Hernández-Arana, Socorro: 1 article (12/2015)
8. Guevara-Gutierrez, Elizabeth: 1 article (12/2015)
9. Ohsaki, Yoshinobu: 1 article (06/2015)
10. Sasaki, Takaaki: 1 article (06/2015)

Related Diseases

1. Urticaria (Hives)
2. Rhinitis
3. Cough
4. Hypersensitivity (Allergy)
5. Pruritus (Itching)

Related Drugs and Biologics

1. Histamine Antagonists (Antihistamines)
2. Histamine (Histamine Dihydrochloride)
3. Adrenal Cortex Hormones (Corticosteroids)
4. Glucocorticoids
5. Leukotriene D4
6. Methotrexate (Mexate)
7. Terfenadine (Seldane)
8. Astemizole
9. Pyrilamine (Mepyramine)
10. Diphenhydramine (Benadryl)

Related Therapies and Procedures

1. Skin Care
2. Plasmapheresis
3. Phototherapy (Light Therapy)
4. Immunotherapy
5. Drug Therapy (Chemotherapy)