Hexosaminidases (Hexosaminidase)

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517 relevant articles (7 outcomes, 29 trials/studies) found for this Bio-Agent

Description: Enzymes that catalyze the hydrolysis of N-acylhexosamine residues in N-acylhexosamides. Hexosaminidases also act on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES.

Also Known As:

Hexosaminidase; Galactosaminidase; Glucosaminidase; Glucosaminidases; Galactosaminidases

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ueda, Yoshihiko: 2 articles (01/2008 - 11/2004)
2.	Zwierz, K: 2 articles (09/2005 - 01/2000)
3.	Hofstra, Julia M: 1 article (08/2008)
4.	Deegens, Jeroen K J: 1 article (08/2008)
5.	Willems, Hans L: 1 article (08/2008)
6.	Wetzels, Jack F M: 1 article (08/2008)
7.	Alptekin, Koksal: 1 article (07/2008)
8.	Birsoy, Bilge: 1 article (07/2008)
9.	Resmi, Halil: 1 article (07/2008)
10.	Ozkara, H Asuman: 1 article (07/2008)

Related Diseases

1.	Neoplasms (Cancer) 07/02/1979 - "Physical properties of human serum hexosaminidases A and B: studies in normal and cancer patients." 09/01/1987 - "Finally, HOCC mediated degradation of radiolabeled ECM was discerned to be dependent upon active hexosaminidase action, since tumor cell mediated degradation of ECM could be inhibited by up to 60% in the presence of this synthetic competitive inhibitor" 01/01/1985 - "N-Acetyl-beta-Glucosaminidase (NAG) activity was investigated in 50 intrathoracic tumors with a histochemical method" 10/01/1984 - "Elevated levels of serum hexosaminidase (beta-2-acetamido-2-deoxy-D-glucoside; N-acetamidodeoxy-D-glucohydrolase, EC 3.2.1.30)(HEX) have been found in patients with cancer" 01/01/1984 - "Serum hexosaminidase as a possible biomarker for human cancer." Get all the results and reference details, order at left...
2.	Pancreatitis 01/01/1992 - "Serum B-N-acetyl hexosaminidase levels in rats with experimental acute pancreatitis, small-bowel ischemia, and small-bowel obstruction." 08/01/1992 - "A positive correlation was found (r = 0.66, P < 0.001) between the highest serum PLA2 activity, as measured early in the course of acute pancreatitis, and the highest N-acetyl-beta-glucosaminidase (NAG):creatinine ratio in the urine" 01/01/1990 - "Intracellular localization and enzymatic activities of lysosomal enzymes (cathepsin B, N-acetyl-beta-glucosaminidase, and beta-glucuronidase) were studied in control rats and after induction of caerulein pancreatitis" 01/01/1992 - "To evaluate the effects of acute pancreatitis on hepatic function and hepatic cellular and subcellular organellar fragility, we studied 1) the hepatic secretion of lysosomal enzymes (beta-glucuronidase, beta-galactosidase, and N-acetyl-beta-glucosaminidase) into bile in the isolated perfused rat liver model; 2) the aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), and lysosomal enzyme levels in the effluent in an isolated liver model; 3) hepatic lysosomal fragility in an in vitro incubation study; and 4) protective effects of a new low molecular weight synthetic protease inhibitor, ONO 3307, against hepatic injury in doses of 2 and 5 mg/kg.h in acute pancreatitis induced by a supramaximal dose of cerulein in rats" Get all the results and reference details, order at left...
3.	Renal Insufficiency 08/01/2008 - "In this study we compared the accuracy of urinary beta-2-microglobulin (U beta 2m) and N-acetyl-beta-glucosaminidase (U beta-NAG) in predicting renal insufficiency and remission rates" 01/01/1989 - "Urinary beta-N-acetyl-D-glucosaminidase (NAG) activity increased from day 3 to day 5, then decreased to normal levels on day 7. Renal ATP concentration and energy charge decreased markedly on day 7. These data indicate that the blood oxygen supply to the tissues began to decrease on day 6 and that renal insufficiency developed in the terminal stage of infection" Get all the results and reference details, order at left...
4.	Shock 03/01/2004 - "OBJECTIVE: Renal tubular damage can be assessed with the aid of urinary dosing of N-acetyl-beta-glucosaminidase (NAG) and it is possible to demonstrate a significant correlation between shock wave and damage to renal parenchyma" 03/01/2004 - "Effect of shock wave reapplication on urinary N-acetyl-beta-glucosaminidase in canine kidney." 01/01/1983 - "Patients in the gram-negative septic shock group and the other shock group both had significantly greater glucosaminidase activity than controls" 03/01/2002 - "Urine was collected for 8 h on the day before and immediately, 1, 7 and 28 days after shock wave exposure (SWE) for the measurement of urine volume, N-acetyl-beta-glucosaminidase (NAG), beta-2-microglobulin (beta2 M), and creatinine" 01/01/1994 - "In order to investigate the effect of electromagnetic shock waves on proximal tubular renal function, we measured the urine levels of the lysosomal enzyme N-acetyl-beta-glucosaminidase (NAG) prior to, 1 hour, 1 day, and 1 week after extracorporeal electromagnetic lithotripsy (ESWL) in 50 patients with urinary stone disease" Get all the results and reference details, order at left...
5.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/02/1978 - "In 23 of 27 cases of the common form of childhood acute lymphoblastic leukemia, the activity of hexosaminidase component I was greatly increased; the activity ratio of hexosaminidase I to hexosaminidase A was greater than 0.5 in 18 of these cases, whereas for other types of leukemia and for all normal cells tested, the ratio was less than 0.2" 09/15/1984 - "The positivity for four cytochemical reactions, acid phosphatase (AcP), alpha-naphtyl acid acetate esterase (ANAE), beta-glucuronidase (BG), and N-acetyl beta-glucosaminidase (NABG) was correlated to first remission duration in 120 children affected with non-T, non-B acute lymphoblastic leukemia (ALL)" Get all the results and reference details, order at left...
238 Diseases and 517 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Glucuronidase
2.	beta-Galactosidase (Lactaid)
3.	Enzymes
4.	Acid Phosphatase
5.	Creatinine
6.	Caerulein (Ceruletide)
7.	Protease Inhibitors (Protease Inhibitor)
8.	Aspartate Aminotransferases (Aspartate Transaminase)
9.	Alanine Transaminase (SGPT)
10.	ONO 3307
275 Drugs and Important Bio-Agents and 320 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Angioplasty (Angioplasties)
2.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
3.	Microspheres (Microsphere)
4.	Ligation
5.	Combination Drug Therapy (Combination Chemotherapy)
13 Therapies and Procedures and 20 more articles analyzed in the Research Interface, order at left...

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