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Hexosaminidases (Hexosaminidase)

Enzymes that catalyze the hydrolysis of N-acylhexosamine residues in N-acylhexosamides. Hexosaminidases also act on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES.
Also Known As:
Hexosaminidase; Galactosaminidase; Glucosaminidase; Glucosaminidases; Galactosaminidases
Networked: 701 relevant articles (8 outcomes, 48 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zwierz, Krzysztof: 10 articles (01/2014 - 11/2006)
2. Waszkiewicz, Napoleon: 7 articles (01/2014 - 01/2011)
3. Olszewska, Ewa: 6 articles (01/2014 - 11/2006)
4. Bonventre, Joseph V: 5 articles (11/2015 - 02/2006)
5. Ouchi, Motoshi: 5 articles (04/2015 - 01/2012)
6. Suzuki, Tatsuya: 5 articles (04/2015 - 01/2012)
7. Oba, Kenzo: 5 articles (04/2015 - 01/2012)
8. Caillaud, Catherine: 5 articles (08/2014 - 11/2005)
9. Kępka, Alina: 5 articles (01/2014 - 01/2011)
10. Szajda, Sławomir Dariusz: 5 articles (01/2014 - 01/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Pancreatitis
01/01/1992 - "Serum B-N-acetyl hexosaminidase levels in rats with experimental acute pancreatitis, small-bowel ischemia, and small-bowel obstruction."
08/01/1992 - "A positive correlation was found (r = 0.66, P < 0.001) between the highest serum PLA2 activity, as measured early in the course of acute pancreatitis, and the highest N-acetyl-beta-glucosaminidase (NAG):creatinine ratio in the urine. "
02/01/2011 - "Marker enzymes [N-acetyl-β-D-glucosaminidase (NAG), cathepsin B and succinate dehydrogenase (SDH)] were assayed in subcellular fractions from control pancreas and in pancreatitis. "
01/01/1990 - "Intracellular localization and enzymatic activities of lysosomal enzymes (cathepsin B, N-acetyl-beta-glucosaminidase, and beta-glucuronidase) were studied in control rats and after induction of caerulein pancreatitis. "
01/01/1992 - "To evaluate the effects of acute pancreatitis on hepatic function and hepatic cellular and subcellular organellar fragility, we studied 1) the hepatic secretion of lysosomal enzymes (beta-glucuronidase, beta-galactosidase, and N-acetyl-beta-glucosaminidase) into bile in the isolated perfused rat liver model; 2) the aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), and lysosomal enzyme levels in the effluent in an isolated liver model; 3) hepatic lysosomal fragility in an in vitro incubation study; and 4) protective effects of a new low molecular weight synthetic protease inhibitor, ONO 3307, against hepatic injury in doses of 2 and 5 mg/kg.h in acute pancreatitis induced by a supramaximal dose of cerulein in rats. "
3. Renal Insufficiency (Renal Failure)
4. Shock
5. Cicatrix (Scar)

Related Drugs and Biologics

1. Glucuronidase
2. beta-Galactosidase (Lactaid)
3. Enzymes
4. Acid Phosphatase
5. Creatinine
6. alpha-L-Fucosidase (Fucosidase)
7. Aspartate Aminotransferases (Aspartate Transaminase)
8. Alanine Transaminase (SGPT)
9. Caerulein (Ceruletide)
10. Protease Inhibitors (Protease Inhibitor)

Related Therapies and Procedures

1. Angioplasty (Angioplasty, Transluminal)
2. Lithotripsy (Extracorporeal Shockwave Lithotripsy)
3. Transplants (Transplant)
4. Transplantation (Transplant Recipients)
5. Microspheres (Microsphere)