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Hexanes

Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.
Also Known As:
Hexane; Isohexane; Isohexanes
Networked: 537 relevant articles (24 outcomes, 83 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lim, Soon Sung: 7 articles (06/2016 - 12/2008)
2. Park, Jung Han Yoon: 7 articles (06/2016 - 12/2008)
3. Park, So Young: 5 articles (06/2016 - 12/2008)
4. Sim, Kae Shin: 5 articles (06/2015 - 01/2011)
5. Kim, Jong-Sang: 5 articles (01/2012 - 12/2008)
6. Hofseth, Lorne J: 4 articles (06/2020 - 01/2012)
7. Nagarkatti, Mitzi: 4 articles (06/2020 - 01/2012)
8. Poudyal, Deepak: 4 articles (06/2020 - 01/2012)
9. Windust, Anthony: 4 articles (06/2020 - 01/2012)
10. Awang, Khalijah: 4 articles (01/2016 - 01/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Edema (Dropsy)
3. Schizophrenia (Dementia Praecox)
02/01/2009 - "The aim of this study was to evaluate further the effect of the mGluR2/3 agonist, LY354740 [(+)-2-aminobicyclo(3.1.0)hexane-2,6-dicarboxylate monohydrate] in animal models relevant to both psychotic and cognitive impairment in schizophrenia. "
04/01/2007 - "Group II metabotropic glutamate (mGlu) receptor agonists, including (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268), have demonstrated efficacy in animal models of anxiety and schizophrenia, and LY354740 decreased anxiety in human subjects. "
11/25/2009 - "The aim of the present study was to compare the effect of mGlu(5) receptor positive allosteric modulator, ADX47273 (S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-methanone), mGluR(2/3) agonist, LY354740 ((1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate monohydrate) and selected neuroleptics in animal models for positive schizophrenia symptoms. "
01/01/2014 - "(1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, also known as LY379268, a group II metabotropic glutamate receptor agonist, has been widely used in neuroscience as a model compound in studies evaluating antipsychotic drugs for the treatment of schizophrenia. "
08/21/2006 - "Acute treatment with LY354740 {1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate monohydrate}, a potent and selective agonist for group II metabotropic glutamate receptors (mGlu2/3), has previously been shown to block some schizophrenia-like effects of N-methyl-D-aspartate (NMDA) receptor antagonists, suggesting a novel therapeutic strategy for schizophrenia. "
4. Pain (Aches)
5. Dengue (Dengue Fever)

Related Drugs and Biologics

1. Methanol (Carbinol)
2. ethyl acetate
3. Chloroform (Trichloromethane)
4. Methylene Chloride (Dichloromethane)
5. Acids
6. Acetone
7. Analgesics (Analgesic Drugs)
8. LY 379268
9. eglumetad
10. 1-Butanol (n Butanol)

Related Therapies and Procedures

1. Therapeutics
2. Traditional Medicine (Folk Remedies)
3. Chemoprevention
4. Laparotomy
5. Spinal Injections