|1.||Shin, Ki Soon: 2 articles (01/2014 - 08/2013)|
|2.||Kim, Joo Yeon: 2 articles (01/2014 - 08/2013)|
|3.||Hong, Seokheon: 2 articles (01/2014 - 08/2013)|
|4.||Kang, Shin Jung: 2 articles (01/2014 - 08/2013)|
|5.||Hwang, Joohyun: 2 articles (01/2014 - 08/2013)|
|6.||Hoppin, Jane A: 2 articles (10/2013 - 02/2007)|
|7.||Richardson, Jason R: 2 articles (09/2008 - 08/2005)|
|8.||Miller, Gary W: 2 articles (09/2008 - 08/2005)|
|9.||Caudle, W Michael: 2 articles (09/2008 - 08/2005)|
|10.||Ghali, Ridha: 1 article (07/2015)|
|1.||Body Weight (Weight, Body)
11/01/1990 - "Diets that contained 25 mg/kg, or more, heptachlor resulted in a significant decrease in feed consumption, while 50 mg/kg, or more, heptachlor caused a significant reduction in body weights. "
11/01/1997 - "The testes in rats treated with 25 mg/kg body weight of heptachlor showed some pathological changes. "
02/01/1995 - "At a dose of 20 mg/kg body weight, heptachlor caused a significant decrease in average body weight (P < 0.01), disrupted and/or prolonged oestrous cycles, decreased mating success (P < 0.001), slightly increased gestation length (P < 0.05) and decreased litter size (P < 0.01)."
02/01/1995 - "Heptachlor affected body weights, cycle patterns, length of gestation period and litter sizes in a dose-related manner. "
02/01/1995 - "Adult female Sprague-Dawley rats were injected with 5 or 20 mg/kg body weight heptachlor solution every other day for up to 18 days. "
|2.||Birth Weight (Birth Weights)
01/01/2005 - "In an ecologic study design, this report compares mortality and cancer incidence rates of children and adolescents born from 1980 to 1982 to rates of children born before and after the heptachlor episode. "
01/01/2005 - "Overall, this report found no indication of higher mortality or cancer incidence among children born during the heptachlor contamination period."
01/01/2005 - "However, a slightly higher occurrence of cancer for the heptachlor-exposed cohort when they were 15-19 years old deserves continued observation in the future. "
01/01/2005 - "Mortality and cancer incidence among children and adolescents in Hawaii 20 years after a heptachlor contamination episode."
12/15/2003 - "With the growing evidence that proliferation accounts for the tumor-promoting effects of many agents, the purpose of this work was to investigate the mechanisms involved in the mitogenic activity of heptachlor in quiescent rat hepatocytes and to understand the properties of this compound as a tumor promoter in the liver. "
06/01/1991 - "Effects of heptachlor, an organochlorine pesticide, on human myeloblastic leukemia ML-1 cells were determined. "
06/01/1991 - "Induction of differentiation in human myeloblastic leukemia ML-1 cells by heptachlor, a chlorinated hydrocarbon insecticide."
01/01/1991 - "The effect of the insecticide heptachlor on ras proto-oncogene expression in human myeloblastic leukemia (ML-1) cells."
01/16/1998 - "Previous studies have shown that heptachlor, a chlorinated hydrocarbon insecticide, is a liver tumor promoter in rats and mice and induces tumor promoting-like alterations in human myeloblastic leukemia cells. "
06/26/1998 - "As a tumor promoter, heptachlor induces human myeloblastic leukemia cells to differentiate, and also down-regulates the tumor suppressor gene p53 in human immune cells. "
|5.||Breast Neoplasms (Breast Cancer)
04/01/1996 - "Taken together, these results suggest that heptachlor and heptachlor epoxide can alter GJIC at the post-translational level, and that, under the conditions of exceeding a threshold concentration in the breast tissue containing 'initiated' cells for a long time and not being counteracted by anti-tumor-promoting chemicals, they could act as breast tumor promoters."
04/01/1997 - "This paper discusses breast cancer patterns in Hawaii in the context of documented episodes of exposure to two endocrine-disrupting chemicals, chlordane/heptachlor and 1,2-dibromo-3-chloropropane (DBCP), at levels that sometimes exceeded federal standards by several orders of magnitude. "
07/01/2015 - "In the unadjusted models, β-hexachlorocyclohexane (β-HCH), hexachlorobenzene, heptachlor, polychlorinated biphenyl congeners 138, 153, and 180, and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) were positively associated with breast cancer risk. "
11/01/2002 - "The present study was therefore planned to determine whether the levels of these pesticides like DDT and its metabolites DDD and DDE, dieldrin, heptachlor, and HCH and its isomers (alpha, beta, and gamma) were higher in blood of breast cancer patients when compared with normal women who did not suffer from major diseases like blood pressure, tuberculosis, diabetes, thyroid dysfunction, arthritis, cancer, etc. and had not undergone any major surgery. "
03/01/2014 - "Activity of the sinusoidal influx transporter OCT1 (organic cation transporter 1) was thus inhibited by endosulfan, chlordane, heptachlor, lindane, and dieldrine, but not by dichlorodiphenyltrichloroethane isomers, whereas those of the canalicular efflux pumps MRP2 (multidrug resistance-associated protein 2) and BCRP (breast cancer resistance protein) were blocked by endosulfan, chlordane, heptachlor, and chlordecone; this latter OC additionally inhibited the multidrug resistance gene 1 (MDR1)/P-glycoprotein (P-gp) activity. "
|5.||Dichlorodiphenyl Dichloroethylene (DDE)
|6.||Pentachlorophenol (Sodium Pentachlorophenate)