Human Viral Hepatitis

INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D).

Also Known As:

Networked: 37 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Chronic Hepatitis B
2.	Hepatitis
3.	Coinfection
4.	Autoimmune Hepatitis
5.	Virus Diseases (Viral Diseases)

Experts

1.	Chen, Jinmei: 1 article (12/2021)
2.	Chen, Xiaohua: 1 article (12/2021)
3.	Lv, Mengjiao: 1 article (12/2021)
4.	Ma, Siyuan: 1 article (12/2021)
5.	Yao, Ting: 1 article (12/2021)
6.	Yu, Yongsheng: 1 article (12/2021)
7.	Zang, Guoqing: 1 article (12/2021)
8.	Zhang, Yi: 1 article (12/2021)
9.	Dessai, Shanti N: 1 article (11/2021)
10.	Roy, Ramaballav: 1 article (11/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Human Viral Hepatitis:

1.	AntigensIBA 01/01/1999 - "Chimpanzees (Pan troglodytes) became established as invaluable models for the study of human viral hepatitis after it was discovered, in 1967, that the chronic hepatitis B antigen carrier state existed in a naturally infected member of this species (1-3). " 08/02/1976 - "To determine whether previously reported cases were caused by human viral hepatitis type A, we tested paired serum samples from two outbreaks for antibody to hepatitis A antigen (anti-HA) by immune adherence hemagglutination (IAHA), recently available test. "
2.	FollistatinIBA 04/01/2001 - "We report the first study of activin-A and follistatin in human viral hepatitis. "
3.	activin AIBA 04/01/2001 - "We report the first study of activin-A and follistatin in human viral hepatitis. "
4.	GalactosamineIBA 11/01/2021 - "D-galactosamine (Ga1N), a well-known hepatotoxic agent, induces liver injury resembling human viral hepatitis usually followed by the regeneration processes. " 01/01/2008 - "D-galactosamine is a well-established hepatotoxicant that induces a diffuse type of liver injury closely resembling human viral hepatitis. " 03/21/2005 - "Galactosamine induced hepatotoxicity resembles human viral hepatitis. " 08/15/1985 - "Galactosamine, a selective hepatotoxin, produces in rats histologic alterations, which show the characteristics of severe human viral hepatitis. " 01/01/1977 - "Galactosamine caused changes in the livers of rats that were similar to those seen in human viral hepatitis. "
5.	Proteins (Proteins, Gene)FDA Link 11/01/2023 - "Hepatitis delta virus (HDV) is the smallest known human virus and causes the most severe form of human viral hepatitis, yet it is still not fully understood how the virus replicates and how it interacts with many host proteins during replication. " 05/01/2008 - "D-Galactosamine (D-GaIN) is a highly selective hepatotoxin that causes liver injury similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. " 01/01/2006 - "D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. "
6.	Uracil NucleotidesIBA 05/01/2008 - "D-Galactosamine (D-GaIN) is a highly selective hepatotoxin that causes liver injury similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. " 01/01/2006 - "D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. "
7.	Tryptophan (L-Tryptophan)FDA Link 06/09/1962 - "Interrelation between tryptophan and nicotinic acid in human viral hepatitis." 10/31/1961 - "[Tryptophan-nicotinic acid metabolism in human viral hepatitis]."
8.	RNA (Ribonucleic Acid)IBA 05/01/2008 - "D-Galactosamine (D-GaIN) is a highly selective hepatotoxin that causes liver injury similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. " 01/01/2006 - "D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. "
9.	Niacin (Nicotinic Acid)FDA LinkGeneric 06/09/1962 - "Interrelation between tryptophan and nicotinic acid in human viral hepatitis." 10/31/1961 - "[Tryptophan-nicotinic acid metabolism in human viral hepatitis]."
10.	Transaminases (Aminotransferases)IBA 12/01/1967 - "[The Hoyt-Morrison test and transaminases in human viral hepatitis and in the hospital personnel engaged in care of the patients]." 11/21/1966 - "[Comparison between the behavior of some serum enzyme activities (guanase and transaminase) and of the Hoyt-Morrison test in human viral hepatitis]."

Therapies and Procedures

1.	Therapeutics 01/01/2023 - "HDV, a satellite of HBV, is responsible for the most severe form of human viral hepatitis, for which curative therapy is still awaited. " 02/01/2003 - "The biology of MHV-2 is quite different from that of human hepatitis viruses; however, these results suggest the beneficial combined therapy of IFN-alpha and IFN-gamma for the treatment of human viral hepatitis." 01/01/2023 - "HDV infection leads to the most aggressive form of human viral hepatitis for which there is no FDA-approved therapy. " 12/22/2021 - "Hepatitis D is the most severe form of human viral hepatitis and currently lacks an efficient therapy. " 01/01/2020 - "We also discuss the evidence base for how host commensal organisms and microbiome therapeutics can impact the prevention and/or treatment of viral infections, such as viral gastroenteritis, viral hepatitis, human immunodeficiency virus (HIV), human papilloma virus (HPV), viral upper respiratory tract infections (URTI), influenza and SARS CoV-2. "
2.	Liver Transplantation 01/01/2016 - "We present the first 2 living-donor liver transplants performed in Turkey in patients with viral hepatitis/human immunodeficiency virus coinfection. "