|1.||Gladwin, Mark T: 13 articles (04/2014 - 09/2002)|
|2.||Steinberg, Martin H: 8 articles (04/2014 - 06/2002)|
|3.||Buchanan, George R: 7 articles (09/2014 - 10/2003)|
|4.||Gordeuk, Victor R: 6 articles (04/2014 - 01/2008)|
|5.||Kato, Gregory J: 6 articles (04/2014 - 01/2006)|
|6.||Hillery, Cheryl A: 5 articles (10/2015 - 12/2003)|
|7.||Fairhurst, Rick M: 5 articles (05/2014 - 01/2008)|
|8.||Wang, Winfred C: 5 articles (02/2013 - 07/2003)|
|9.||Hebbel, Robert P: 5 articles (03/2012 - 01/2003)|
|10.||Safo, Martin K: 4 articles (10/2014 - 09/2008)|
|1.||Sickle Cell Anemia (Hemoglobin S Disease)
01/01/1983 - "There is no specific therapy for sickle cell disease, and there is no evidence that sickle hemoglobin screening by conventional methods will lead to a significant reduction in the number of children with sickle cell disease. "
01/01/1992 - "Since cell shrinkage adversely influences red cell rheology, it is unlikely that this class of compounds, despite its ability to inhibit hemoglobin S polymerization, will prove useful in the treatment of sickle cell disease."
08/01/2008 - "Using this improved approach, we also generated hES-like cells from homozygous fibroblasts containing the sickle cell anemia mutation Hemoglobin Sickle. "
03/01/2015 - "Studies of hemoglobin S haplotypes in African subpopulations have potential implications for patient care and our understanding of genetic factors that have shaped the prevalence of sickle cell disease (SCD). "
01/01/2013 - "The goal of this study was to evaluate the quality of life of sickle cell disease patients (hemoglobin SS and SC) and their sociodemographic and clinical characteristics. "
08/01/2006 - "Hemoglobin S was associated with protection against mild malaria attacks. "
01/01/1992 - "A study was carried out on susceptibility of sicklemia patients to Plasmodium falciparum (PF) malaria in 151 hemoglobin S carriers (homozygous and heterozygous), assisted at the Cotonú Hospital, Benin, for 1 year. "
07/01/2012 - "We report the case of a woman with both malaria and hemoglobin S."
04/29/2011 - "Sickle hemoglobin confers tolerance to Plasmodium infection."
02/01/2009 - "Malaria-infected red blood cells (RBCs) share surface characteristics of hemoglobin S-containing cells. "
01/01/2013 - "The second patient had hemoglobin SS and two acute ischemic strokes. "
03/01/2007 - "Although overt stroke occurs in 1 in 10 children with Hemoglobin SS, "silent cerebral infarcts" are even more frequent. "
11/01/2006 - "TCD screening of all children with SCD, and initiation and maintenance of chronic transfusion to maintain hemoglobin S below 30% in the high-risk group, is the only proven prevention strategy for stroke in SCD. "
05/01/2005 - "Cerebral vascular accident (CVA) or stroke is one of the major complications of hemoglobin SS (Hgb SS) disease. "
07/01/2004 - "Hemoglobin SS is the most severe form of SCD and carries an increased risk for stroke. "
|4.||Sickle Cell Trait
07/01/2003 - "Among children with sickle cell trait, percentage of hemoglobin S was significantly greater in children who had tortuosity than percentage of hemoglobin S in children who had normal blood vessels at MR angiography (P <.03). "
11/01/2010 - "These studies included 96 patients with hemoglobin SS, SC, and sickle cell trait (AS). "
01/01/2015 - "Sickle cell trait (heterozygosity for hemoglobin S, n = 268) was compared with no sickle cell trait (n = 3748). "
02/24/2011 - "Observed differences indicate the effect of the polymerization of sickle hemoglobin as well as possible changes in the organization of the cell cytoskeleton associated with the sickle cell trait."
02/01/1984 - "However, for purposes of the regulation, sickle cell trait is defined as 41% or less S hemoglobin. "
|5.||Falciparum Malaria (Plasmodium falciparum Malaria)
03/01/2009 - "African-Americans (n = 57), nonAfrican-Americans (n = 33), individuals with and without hemoglobin S (n = 15 and n = 12), and children with P falciparum malaria (n = 97) were tested. "
01/01/2003 - "Heterozygosity for the mutant sickle hemoglobin confers protection from severe Plasmodium falciparum malaria. "
02/01/1982 - "The erythrocytes of patients with sickle hemoglobin, diabetes, and Falciparum malaria adhere disproportionately to endothelial cells. "
01/01/1980 - "Population studies in Cameroon: hemoglobin S, glucose-6-phosphate dehydrogenase deficiency and falciparum malaria."
11/01/2005 - "falciparum malaria was close to baseline in children heterozygous with respect to the mutation underlying the hemoglobin S variant and homozygous with respect to the mutation underlying alpha(+)-thalassemia. "
|2.||Fetal Hemoglobin (Hemoglobin F)
|4.||beta-Globins (beta Globin)
|1.||Blood Transfusion (Blood Transfusions)
|2.||Drug Therapy (Chemotherapy)
|4.||Homologous Transplantation (Allograft)