Hemofiltration

Extracorporeal ULTRAFILTRATION technique without HEMODIALYSIS for treatment of fluid overload and electrolyte disturbances affecting renal, cardiac, or pulmonary function.

Also Known As:

Arteriovenous Hemofiltrations; Hemofiltration, Arteriovenous; Hemofiltration, Venovenous; Hemofiltrations; Venovenous Hemofiltrations; Arteriovenous Hemofiltration; Venovenous Hemofiltration

Networked: 1123 relevant articles (82 outcomes, 117 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Ronco, Claudio: 16 articles (01/2021 - 01/2002)
2.	Bellomo, Rinaldo: 16 articles (10/2018 - 01/2002)
3.	Humes, H David: 9 articles (01/2012 - 05/2002)
4.	Vincent, Jean-Louis: 8 articles (10/2016 - 04/2003)
5.	Bellomo, R: 8 articles (04/2008 - 01/2000)
6.	Honore, Patrick M: 7 articles (12/2019 - 07/2002)
7.	Joannes-Boyau, Olivier: 7 articles (12/2019 - 01/2004)
8.	Wang, Fei: 6 articles (01/2022 - 10/2016)
9.	Zhang, Yucai: 6 articles (01/2022 - 02/2015)
10.	Fissell, William H: 6 articles (10/2018 - 05/2002)

Related Diseases

1.	Septic Shock (Toxic Shock Syndrome) 02/01/2002 - "Pro/con clinical debate: is high-volume hemofiltration beneficial in the treatment of septic shock?" 01/01/2013 - "This study used cardiovascular measurements recorded during a porcine trial studying the efficacy of large-pore hemofiltration for treating septic shock. " 09/01/2006 - "Improved short-term outcomes with early use of isovolemic hemofiltration in patients with septic shock." 01/01/1997 - "In some animal models of experimental septic and non-septic shock, (short-term) hemodialysis and hemofiltration were found to improve hemodynamics and/or gas exchange. " 01/01/1993 - "Although hemofiltration has been shown to improve hemodynamics of experimental septic shock, convincing evidence that hemofiltration improves outcome of ICU patients is lacking. "
2.	Critical Illness (Critically Ill) 01/01/1992 - "The best clearance rates are achieved by intermittent hemodialysis, but continuous hemofiltration is a simple, safe and effective alternative and is sometimes tolerated better by critically ill infants." 12/01/2012 - "Dialytic dose of continuous RRT has been recently and definitely standardized to 20-25 ml/kg per hour (dialysis or hemofiltration), however, application to clinical practice still needs to be improved and new evidence on net ultrafiltration prescription showed that fluid balance may be as important as blood purification in critically ill patients with renal dysfunction. " 05/28/2019 - "BACKGROUND Studies have been carried out to assess the efficacy of high-volume hemofiltration (HVHF) among critically ill patients. " 01/01/2022 - "Literature Review of the Efficacy of High-Volume Hemofiltration in Critically Ill Pediatric Patients." 11/01/1999 - "CRRT remains the treatment of choice in this group of critically ill patients because of improved cardiovascular and intracranial stability when compared with conventional intermittent hemofiltration and/or dialysis and effective solute clearances when compared with forms of peritoneal dialysis. "
3.	Acute Kidney Injury (Acute Renal Failure) 07/01/2022 - "This study aims to determine whether early high-dose continuous venous-venous hemofiltration (CVVH) alleviates the alterations in CD4+ T lymphocyte subsets in septic patients combined with acute kidney injury. " 06/18/2014 - "The aim of this study was to compare the efficacies of goal-directed renal replacement therapy (GDRRT) and daily hemofiltration (DHF) for treating acute kidney injury (AKI) patients after cardiac surgery. " 04/01/2011 - "Humes and colleagues developed BTD, treated acute kidney injury patients with multiorgan failure by continuous hemofiltration (CHF) in conjunction with BTD, and reported a significantly higher survival rate than that by CHF with BTD without cells in the Food and Drug Administration phase IIa trial. " 01/01/2008 - "Design and challenges of the Randomized Evaluation of Normal versus Augmented Level Replacement Therapy (RENAL) Trial: high-dose versus standard-dose hemofiltration in acute renal failure." 01/01/2007 - "Hemofiltration (HF) has been reported to decrease the risk of acute renal failure in patients with CKD receiving a contrast load, but the studies are methodologically flawed. "
4.	Chronic Kidney Failure (Chronic Renal Failure) 05/01/2003 - "Chronic hemofiltration is a relatively simple MRRT option that may offer significant benefits for many patients who have end-stage renal disease (ESRD) and deserves closer consideration for these patients." 01/01/1985 - "Hemofiltration--an improved method of treatment for chronic renal failure." 09/01/2008 - "Given the paucity of prospective randomized controlled trials assessing comparative performances of different dialysis techniques, we compared on-line high-flux hemofiltration (HF) with ultrapure low-flux hemodialysis (HD), assessing survival and morbidity in patients with end-stage renal disease (ESRD). " 03/01/2005 - "We performed a systematic review of randomized controlled trials (RCTs) comparing hemodialysis (HD), hemofiltration (HF), hemodiafiltration (HDF), and acetate-free biofiltration (AFB) in the treatment of patients with end-stage renal disease to assess their clinical effectiveness. " 01/01/2004 - "Daily hemofiltration for end-stage renal disease: a feasibility and efficacy trial."
5.	Sepsis (Septicemia) 01/01/2007 - "Perhaps this can explain why some very recent studies using high-permeability hemofiltration in sepsis have not been effective in improving hemodynamics and survival in septic acute animal models. " 05/01/2018 - "The aim of this study was to compare the safety and the efficacy of two methods of continuous blood purification (CBP), continuous veno-venous hemofiltration (CVVH) and high volume hemofiltration (HVHF), for treatment of infantile sepsis. " 05/01/2005 - "It was agreed that conventional CVVH has sufficiently been shown not to be effective in SIRS/Sepsis in the absence of concomitant ARF and that other therapies such as plasmapheresis or high-volume hemofiltration or coupled plasma filtration adsorption appear more promising and should be tested in multicentre randomized controlled trials. " 04/01/2020 - "In order to evaluate the effect between routine continuous renal replacement therapy (CRRT) and high-volume hemofiltration (HVHF) in children with sepsis, we performed out this prospective, randomized, controlled, open-label trial. " 01/01/2018 - "The study aimed to assess the clinical benefits of high-volume hemofiltration (HVHF) in pediatric patients with severe sepsis compared with standard-volume continuous veno-venous hemofiltration (CVVH). "

Related Drugs and Biologics

1.	Cytokines
2.	Oxygen (Dioxygen)
3.	Albumins
4.	Interleukin-6 (Interleukin 6)
5.	Bilirubin
6.	Lactic Acid (Lactate)
7.	Dopamine (Intropin)
8.	Anti-Bacterial Agents (Antibiotics)
9.	Therapeutic Uses
10.	Proteins (Proteins, Gene)

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Therapeutics
3.	Plasmapheresis
4.	Continuous Renal Replacement Therapy
5.	Peritoneal Dialysis