Hemerythrin

A non-heme iron protein consisting of eight apparently identical subunits each containing 2 iron atoms. It binds one molecule of oxygen per pair of iron atoms and functions as a respiratory protein.

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Caldas Nogueira, Maria Luiza: 1 article (09/2020)
2.	Davidson, Victor L: 1 article (09/2020)
3.	Ma, Zhongxin: 1 article (09/2020)
4.	Marchi-Salvador, Daniela Priscila: 1 article (09/2020)
5.	Guan, Yanlong: 1 article (01/2018)
6.	Hu, Jinyong: 1 article (01/2018)
7.	Huang, Jinling: 1 article (01/2018)
8.	Li, Ping: 1 article (01/2018)
9.	Liu, Li: 1 article (01/2018)
10.	Running, Mark P: 1 article (01/2018)

Related Diseases

1.	Iron Deficiencies 01/01/2015 - "In Arabidopsis (Arabidopsis thaliana), BRUTUS (BTS), which contains three hemerythrin (HHE) domains and a Really Interesting New Gene (RING) domain, interacts with basic helix-loop-helix transcription factors that are capable of forming heterodimers with POPEYE (PYE), a positive regulator of the iron deficiency response. " 07/01/2014 - "Iron Deficiency-responsive Element-binding Factor 1 (IDEF1) and Hemerythrin motif-containing Really Interesting New Gene- and Zinc-finger proteins (HRZs)/BRUTUS (BTS) have recently emerged as candidate iron sensors because of their functions as potent regulators of iron deficiency responses and their iron-binding properties. "
2.	Septic Shock (Toxic Shock Syndrome) 10/15/2004 - "One protein found to be up-regulated after septic shock was identified, through a combination of Edman degradation, mass spectrometry, and molecular cloning, as a novel member of the hemerythrin family, a group of non-heme-iron oxygen transport proteins found in four invertebrate phyla: sipunculids, priapulids, brachiopods, and annelids. "
3.	Neoplasms (Cancer) 01/01/2016 - "The hemerythrin-like domain of F-box and leucine-rich repeat protein 5 (FBXL5), an E3 ubiquitin ligase subunit, has critical roles in the regulation of cancer cells metastasis and chemoresistance by targeting diverse substrates for ubiquitin-mediated destruction. "
4.	Neoplasm Metastasis (Metastasis) 01/01/2016 - "The hemerythrin-like domain of F-box and leucine-rich repeat protein 5 (FBXL5), an E3 ubiquitin ligase subunit, has critical roles in the regulation of cancer cells metastasis and chemoresistance by targeting diverse substrates for ubiquitin-mediated destruction. "
5.	Infections 09/15/2020 - "The Rv2633c gene of Mycobacterium tuberculosis, which plays a role in infection, encodes a hemerythrin-like protein (HLP). "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Oxygen (Dioxygen)
3.	Iron
4.	Basic Helix-Loop-Helix Transcription Factors
5.	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
6.	Ubiquitin
7.	Heme (Haem)
8.	Glutaral (Glutaraldehyde)
9.	Elements
10.	Carrier Proteins (Binding Protein)