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Heme Oxygenase (Decyclizing) (Heme Oxygenase)

A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt. EC 1.14.99.3.
Also Known As:
Heme Oxygenase; Oxygenase, Haem; Oxygenase, Heme; Haem Oxygenase; Heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
Networked: 817 relevant articles (40 outcomes, 92 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Ndisang, Joseph Fomusi: 24 articles (01/2016 - 05/2003)
2. Jadhav, Ashok: 15 articles (01/2014 - 01/2007)
3. Abraham, Nader G: 12 articles (01/2015 - 01/2003)
4. Potter, Richard F: 8 articles (11/2005 - 05/2002)
5. Otterbein, Leo E: 7 articles (08/2015 - 02/2003)
6. Wong, Ronald J: 7 articles (05/2015 - 10/2002)
7. Stec, David E: 7 articles (01/2015 - 04/2005)
8. Takahashi, Toru: 7 articles (05/2013 - 02/2002)
9. Bihari, Aurelia: 7 articles (11/2005 - 05/2002)
10. Vreman, Hendrik J: 6 articles (05/2015 - 10/2002)

Related Diseases

1. Inflammation
2. Hypertension (High Blood Pressure)
3. Sepsis (Septicemia)
4. Ischemia
5. Shock

Related Drugs and Biologics

1. Carbon Monoxide
2. tin protoporphyrin IX
3. Nitric Oxide Synthase (NO Synthase)
4. Hemin (Panhematin)
5. Bilirubin
6. Heme (Haem)
7. Cytokines
8. Angiotensin II
9. zinc protoporphyrin
10. tin mesoporphyrin

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Phototherapy (Light Therapy)
3. Transplantation (Transplant Recipients)
4. Spinal Injections
5. Ligation