|2.||Hypotension (Low Blood Pressure)
|1.||Spotnitz, Henry M: 9 articles (07/2011 - 06/2004)|
|2.||Cabreriza, Santos E: 9 articles (07/2011 - 06/2004)|
|3.||Wahren-Herlenius, Marie: 8 articles (01/2014 - 04/2004)|
|4.||Sonesson, Sven-Erik: 7 articles (05/2012 - 04/2004)|
|5.||Weinberg, Alan D: 7 articles (05/2010 - 06/2004)|
|6.||Quinn, T Alexander: 6 articles (05/2010 - 08/2004)|
|7.||Buyon, Jill P: 5 articles (01/2016 - 08/2005)|
|8.||Curtis, Lauren J: 5 articles (05/2006 - 06/2004)|
|9.||Berberian, George: 4 articles (09/2007 - 09/2005)|
|10.||Rabkin, David G: 4 articles (05/2006 - 06/2004)|
05/01/2010 - "In active elderly patients with complete heart block, DDD pacing is associated with improved quality of life and systolic ventricular function compared with VVI pacing."
10/01/1995 - "In active elderly patients with complete heart block both DDD and VVIR pacing are associated with improved exercise performance compared with fixed rate VVI pacing. "
06/01/2012 - "Our study revealed that in active elderly patients with complete heart block, DDD pacing and VVIR pacing yielded similar improvements in QoL and exercise performance. "
04/01/1986 - "Electrophysiologic studies were performed before DDD pacemaker implantation in 50 patients with symptomatic heart block. "
09/01/2013 - "We present the case of a 72-year-old male who underwent a permanent transvenous DDD pacemaker implantation for symptomatic complete heart block. "
|2.||Verapamil (Calan)FDA LinkGeneric
05/01/1989 - "An in situ experimental study of the heart has demonstrated that verapamil++ (0.3 mg/kg), administered intravenously to dogs with complete transverse heart block one day after two-step occlusion of the left descending coronary artery either produced a 15-30% drop in the incidence of abnormal ventricular activity (AVA) in some experiments, or had no effect on the latter in others. "
12/01/2003 - "[Atrioventricular complete heart block developed due to verapamil use together with honey consumption]."
05/01/1989 - "One subject was withdrawn because of asymptomatic second degree heart block on day 3 of verapamil treatment. "
01/01/1988 - "The larger doses of verapamil, however, will be contradicted because of the slowing of AV node and the likelihood of complete heart block."
06/01/1986 - "Significant prolongation of the PR interval was observed in all verapamil groups, with second or third degree heart block in some of the higher-dose animals.(ABSTRACT TRUNCATED AT 250 WORDS)"
01/01/2014 - "Letter to the Editor in response to the article "Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials." by Gleicher N, Elkayam U, Autoimmun Rev. 2013 Sep;12(11):1039-45."
09/01/2013 - "Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials."
03/01/2012 - "Recurrence rates of only 10-20% despite persisting maternal antibodies indicate that additional factors are critical for the establishment of heart block. "
03/29/2011 - "Prolongation of the atrioventricular conduction in fetuses exposed to maternal anti-Ro/SSA and anti-La/SSB antibodies did not predict progressive heart block. "
09/01/2010 - "Perfusion of human foetal heart with anti-Ro/SSA antibodies induces transient heart block. "
|4.||Atropine (Hyoscyamine)FDA LinkGeneric
06/01/1980 - "In every dog during any of the three reflexes heart block was consistently observed after the normal slowing response of the sinus node had been selectively eliminated by the direct perfusion of 10 microgram of atropine into the sinus node artery. "
12/01/2009 - "Proposed measures to prevent this complication include pretreatment with atropine or prophylactic placement of transvenous pacemakers in patients with underlying heart block and patients with contraindications to atropine use."
02/01/2008 - "Although the heart block was resolved after 2 doses of atropine, prolonged P-R and Q-Tc intervals persisted into the immediate postoperative period but returned to baseline within 4 hours. "
09/01/2002 - "Our criteria of inclusion requires the existence of patients with a second or third degree heart block, who are less than 40 years old at the time of diagnosis, which is not totally regressive in the effort test and the atropine injection, and whose congenital origin was strongly suspected because of the notion of slow pulse during their youth and the absence of acquired affect which enables us to explain this disease. "
03/01/2002 - "Heart block occurs usually at the level of the atrioventricular node but often is unresponsive to atropine sulfate. "
|5.||Congenital heart blockIBA
10/01/1998 - "Therapy of established congenital complete heart block in the fetus has resulted in improved survival but persistence of heart block. "
01/01/2004 - "To study the autoimmune response in mothers of children with isolated congenital heart block (CHB) and heart block (HB) diagnosed postnatally. "
05/01/2012 - "A combination therapy to treat second-degree anti-Ro/La-related congenital heart block: a strategy to avoid stable third-degree heart block?"
01/01/2010 - "Twelve patients aged 20.0 + or - 7.4 years with congenital heart block (group I) and six patients aged 22.7 + or - 11.0 years with surgically acquired heart block (group II) with RV pacing were studied. "
09/01/2009 - "Eighteen patients aged 19 +/- 7 years with congenital heart block (group I), 9 aged 21 +/- 11 years with acquired heart block after congenital heart surgery (group II), and 15 healthy control subjects (group III) were studied. "
|6.||Neonatal Systemic lupus erythematosusIBA
09/01/2015 - "Treatment of Congenital Complete Atrioventricular Heart Block With Permanent Epicardial Pacemaker in Neonatal Lupus Syndrome."
05/12/2011 - "After labour, the neonate was examined for complications including complete heart block and neonatal lupus. "
01/01/2009 - "The neonatal lupus disease process is transient, although third-degree heart block, once established, is permanent. "
01/01/2009 - "The most common severe manifestation of neonatal lupus is third-degree heart block, which usually begins during the second trimester of gestation. "
10/01/2006 - "In neonatal lupus, 3% of infants whose mothers are antibody positive develop complete heart block. "
|7.||Dexamethasone (Maxidex)FDA LinkGeneric
09/01/2004 - "Oral dexamethasone treatment could not prevent progression to complete heart block and was associated with a number of complications.A review of the literature revealed 19 studies (including ours) in which 93 cases of fetal heart block were treated with maternal steroid therapy. "
03/29/2011 - "With this rationale in mind, dexamethasone has been advocated by others to treat prolonged fetal AV conduction >2 z-scores, consistent with first-degree heart block. "
08/01/2005 - "Dexamethasone did not improve the degree of heart block in any of the six fetuses treated. "
07/01/2004 - "First-degree heart block in the fetus of an anti-SSA/Ro-positive mother: reversal after a short course of dexamethasone treatment."
06/01/2004 - "We report for the first time a fetal case with sustained regression from isolated complete to first-degree heart block on transplacental treatment with high-dose dexamethasone. "
|8.||Isoproterenol (Isoprenaline)FDA LinkGeneric
01/04/1969 - " majority of patients with chronic heart block are elderly, and in view of the complexity of pacing systems, and the need for skilled supervision of paced patients, oral long-acting isoprenaline remains of value in the longterm management of chronic heart block, provided patients are carefully selected for this form of therapy."
01/04/1969 - "A study of 203 patients with chronic heart block treated with oral long-acting isoprenaline showed that 85 (42%) were maintained satisfactorily on the drug for a mean period of 18.2 months. "
04/01/2007 - "At specified time points after complete heart block induction and pacing initiation, steady-state QT interval measurements and variability as well as dynamic QT interval adaptation to abrupt heart rate acceleration were assessed in the absence and presence of isoproterenol. "
01/01/1979 - "The treatment was primarily conservative; 22 of the 39 patients with complete heart block were given isoproterenol and two received temporary pacemakers. "
11/01/1975 - "Atrial and ventricular pacemaker function was studied in 20 patients with idiopathic chronic complete heart block using the rate response to an intravenous bolus dose of isoprenaline (5 mug/70 kg bodyweight). "
10/01/1998 - "Relevant investigations revealed marked hyponatraemia (serum sodium concentration 122 mmol litre-1) and second-degree heart block (Mobitz I). "
03/01/1965 - "THE ROLE OF BRADYCARDIA IN THE RETENTION OF SODIUM AND WATER IN COMPLETE HEART BLOCK WITH AND WITHOUT HEART FAILURE IN HUMAN BEINGS."
09/01/2008 - "However, CN/Tg-iNOS(-/-) mice had improved systolic performance (P < 0.001) and less heart block (P < 0.0001); larger sodium current density and lower serum TNF-alpha levels (P < 0.03); and less apoptosis (P < 0.01) resulting in improved survival (P < 0.0003). "
08/01/1988 - "A statistically significant decrease in serum sodium levels was also found in groups 2 and 4. One dog in group 4 developed intermittent second-degree heart block after the final dose of dantrolene. "
06/01/1980 - "Reflex heart block was studied in 20 dogs anesthetized with sodium pentobarbital and in 5 trained unanesthetized dogs. "
|10.||Glucagon (Glukagon)FDA Link
12/01/1973 - "Effect of glucagon on infants and children with atrioventricular heart block."
05/01/1971 - "Effect of glucagon on dogs with acute and chronic heart block."
04/01/1971 - "Glucagon in heart block."
01/01/1971 - "Hemodynamic effect of glucagon in patients with chronic complete heart block."
01/01/1979 - "The work demonstrates the efficacy of glucagon in acute myocardial infarction and its complications, particularly in bradycardia, hypotension, disorders of cardiac rhythm and conduction, cardiogenic shock, cardiac insufficiency in complete atrioventricular heart block and recurrent forms of ventricular fibrillation. "
|1.||Drug Therapy (Chemotherapy)
11/01/1992 - "Heart block patients did not differ from the non-heart block group with respect to age, interval from diagnosis or bone marrow harvest to transplant, cardiac risk factors, pretransplant electrocardiograms or radionuclide angiograms, transplant chemotherapy regimens or serum chemistry values. "
02/01/2003 - "Massive metastatic intracardiac lymphoma presenting with complete heart block with resolution following chemotherapy."
03/01/1996 - "This report presents the first case of complete heart block due to lymphoma that responded to surgery and chemotherapy with return of normal atrial ventricular conduction."
10/01/1985 - "The ineffectiveness of single low-dose chemotherapy is demonstrated by the non-response of lung metastases beyond the irradiation fields (heart block, diaphragm). "
02/01/1973 - "Complete heart block in acute myocardial infarction: drug therapy."
01/01/2007 - "This problem of early fatality from heart block was completely eliminated with the use of a myocardial electrode in combination with an external plug-in electric stimulator. "
07/01/1975 - "The present study is concerned with in vivo testing of the complete pacemaker system, by means of both myocardial and endocranial electrodes, in 20 dogs with and without induced heart block. "
01/01/2008 - "We report a case of a patient in which the presence of superior left vena cava and the absence of the superior vena cava was detected during the implantation of a pacemaker for the correction of a total heart block, which led us to use a different technique for the fixation of the ventricular electrode. "
08/01/2002 - "A ring electrode was used to stimulate this fat pad intraoperatively during sinus rhythm to produce transient complete heart block. "
09/01/1994 - "Using a fetal monitor, bedside patient monitor, spiral electrode, and a special cable described herein, we obtained direct fetal electrocardiograms from two fetuses with autoimmune heart block. "
12/01/1982 - "In nine anesthetized and ventilated dogs heart block was induced at thoracotomy, a pacemaker was inserted, and an electromagnetic flow transducer was placed round the main pulmonary artery. "
12/01/1982 - "Methods for producing complete heart block in experimental animals have usually required thoracotomy to gain access to the intracardiac conduction system. "
01/21/1967 - "Currently it is the authors' method of choice in the treatment of heart block; thoracotomy is now obsolete unless a synchronous pacemaker is needed or a permanent transvenous pacer cannot be inserted."
07/01/1972 - "A method of epicardial pacing without thoracotomy: treatment of heart block in patients with tricuspid valve prosthesis."
12/01/1982 - "We conclude that this closed chest method is a safe and reliable alternative for production of complete heart block requiring thoracotomy, thereby providing an important new means for both acute and chronic experimental studies requiring complete heart block for the improved elucidation of mechanisms and management of cardiovascular diseases."
01/01/2008 - "Patients diagnosed with symptomatic heart block but not treated with artificial cardiac pacemaker insertion were excluded from the study. "
01/01/1968 - "A hemodynamic and metabolic study in patients with complete heart block and artificial pacemaker."
06/01/1967 - "[Experimental studies on the application of the artificial pacemaker for complete heart block]."
01/01/2008 - "Twenty-three patients who were diagnosed with symptomatic heart block and surgically treated with permanent artificial cardiac pacemaker in National Cardiothoracic Centre, Enugu, between April 2001 and March 2006 had their case notes retrospectively reviewed and information entered into a proforma. "
01/01/1993 - "The predictability of artificial pacemaker block based on atrial rate behaviour during exercise in heart block and VVI pacing has also been determined. "