Induced Heart Arrest (Cardioplegia)

Subscribe to Selected New Research on Induced Heart Arrest

1541 relevant articles (121 outcomes, 185 trials/studies) found for this Therapy

Description: A procedure to stop the contraction of MYOCARDIUM during HEART SURGERY. It is usually achieved with the use of chemicals (CARDIOPLEGIC SOLUTIONS) or cold temperature (such as chilled perfusate).

Also Known As:

Cardioplegia; Heart Arrest, Induced; Induced Cardiac Arrest; Cardioplegias; Cardiac Arrest, Induced

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 4

Thoracic Surgical Procedures: 43

Cardiac Surgical Procedures: 203

Induced Heart Arrest: 1541

Deep Hypothermia Induced Circulatory Arrest: 243

Cardiovascular Surgical Procedures: 18

Cardiac Surgical Procedures: 203

Induced Heart Arrest: 1541

Deep Hypothermia Induced Circulatory Arrest: 243

Experts

1.	Angelini, Gianni D: 2 articles (02/2008 - 08/2002)
2.	Januska, J: 2 articles (06/2004 - 01/2000)
3.	Klövekorn, W P: 2 articles (10/2003 - 10/2000)
4.	Bauer, E P: 2 articles (10/2003 - 10/2000)
5.	Roth, M: 2 articles (10/2003 - 10/2000)
6.	Shaw, Sidney: 1 article (09/2008)
7.	Rieben, Robert: 1 article (09/2008)
8.	Carrel, Thierry: 1 article (09/2008)
9.	Meier, Pascal: 1 article (09/2008)
10.	Berdat, Pascal: 1 article (09/2008)

Related Diseases

1.	Ischemia 09/01/1998 - "The experimental results suggest that such interventions could be beneficial in clinical situations such as cardioplegia, heart preservation, or recovery from ischemia." 01/01/1997 - "Left ventricular developed pressure (LVDP) at 30 min reperfusion after unprotected ischemia was significantly improved by IPC, while the recovery of LVDP at 30 min reperfusion after cardioplegia was comparable between control and IPC-treated hearts" 02/01/1996 - "A significant reduction in endothelium-dependent vascular function was observed after 40 minutes of ischemia (-31.8% +/- 6.6% vs -50.4% +/- 1.6% in control hearts, p < 0.05), and again this was improved by cardioplegia (-45.0% +/- 3.4%, p < 0.05 vs ischemic group)" 12/01/2003 - "Preconditioning with cardioplegia is more effective in reducing apoptosis than is preconditioning with ischemia in the human myocardium." 11/01/1994 - "With the continuing search for superior methods of myocardial protection, we compared the protective efficacy of ischemic preconditioning with that of St Thomas' cardioplegia, alone and in combination, against vascular and myocyte injury during ischemia and reperfusion" Order ALL the reference details at left...
2.	Hypothermia 08/01/1992 - "The findings suggest that, even though no consensus exists about its ideal composition, cardioplegia in conjunction with hypothermia is currently the strategy most often used for pediatric myocardial protection." 01/01/1987 - "Cardioplegia is most effective when combined with the additive properties of hypothermia, which plays a significant role in decreasing myocardial metabolism" 09/01/1996 - "RESULTS: In hypertrophied hearts, protection by topical hypothermia alone resulted in significantly improved postischemic recoveries of maximum left ventricular pressure and rate of pressure rise compared with the method of slow cooling or application of cardioplegia (40.6% +/- 5.0% and 38.1% +/- 5.9%, mean +/- standard error of the mean; p < 0.05)" 03/01/1983 - "The small increase in risk compared to the significant improvement from the combined approach has led to the following principles: coronary arteriography on all adult patients requiring valvular operations; bypass of all significant coronary lesions; restoration of valvular function and hemodynamics; and myocardial preservation with cold cardioplegia during a single period of cross clamping, topical cold, and systemic hypothermia." 12/01/1992 - "These techniques deviate from conventional practice, and they infer that normothermia is superior to hypothermia, retrograde cardioplegia is more advantageous than antegrade administration, and continuous cardioplegic delivery is preferable to intermittent dosage" Order ALL the reference details at left...
3.	Stroke (Strokes) 11/01/1989 - "However, the left ventricular stroke work index, when expressed as a function of its prebypass control value, was significantly improved (p less than 0.01) in the cohort administered combined cardioplegia" 04/01/1984 - "We found slight but significant improvement in the blood cardioplegia group regarding left ventricular stroke work index" 01/01/1987 - "Postoperatively, blood cardioplegia resulted in better LV performance (higher LV stroke work index at a similar LV end-diastolic volume index [EDVI]) (p = .01), better LV systolic function (similar systolic blood pressures at smaller LV end-systolic volume indexes [ESVI]), (p = .04), and improved LV diastolic function (lower left atrial pressures at similar LVEDVIs) (p = .03).(ABSTRACT TRUNCATED AT 250 WORDS)" 06/01/2003 - "RESULTS: Compared with normocalcemic cardioplegia, hypocalcemic cardioplegia improved preservation of left ventricular (LV) systolic function (88% +/- 2.2% vs 64% +/- 15% recovery of end-systolic elastance, p = 0.02), diastolic function (12% +/- 21% vs 38% +/- 11% increase in end-diastolic stiffness, p = 0.04), and myocardial contractility (97% +/- 9.6% vs 75.2% +/- 13% recovery of preload recruitable stroke work [PRSW], p = 0.04)" 07/01/1995 - "Furthermore, if only warm (> 33 degrees C) versus cold (< 30 degrees C) systemic perfusion is examined in all studies for the incidence of stroke irrespective of cardioplegia temperature or antegrade versus retrograde coronary perfusion (warm 2.1%; cold 1.6%), the above study remains a significant outlier" Order ALL the reference details at left...
4.	Heart Arrest (Cardiac Arrest) 03/01/1976 - "Because of the significantly improved preservation of the fine structure of the heart and retardation of ischaemically provoked changes in cardiac metabolism, the method of inducing heart arrest by cardioplegia should also clinically be given preference to methods of arresting the heart by ischaemia." 08/01/2000 - "And cardioplegia technique employed these components improved clinical results of open heart surgery except special cases which require longer cardiac arrest" 11/01/2007 - "Aim of the study was to develop an in vivo model of rat CPB with hypothermic cardiac arrest and the use of cardioplegia" 10/01/1996 - "To study this, we compared the effects of continuous and intermittent antegrade warm (37 degrees C) blood cardioplegia on functional recovery after prolonged cardiac arrest (180 minutes)" 03/01/1984 - "The present study favours the use of cold blood cardioplegia which preserves both the coronary endothelium and the myocardial energy sources during ischaemic cardiac arrest." Order ALL the reference details at left...
5.	Reperfusion Injury 01/01/1990 - "The study shows that previously infarcted hearts are susceptible to ischemic damage even after 2 h of regular hypothermic, ischemic cardioplegia and that a gentle reperfusion technique significantly ameliorates reperfusion injury." 01/01/2006 - "Controlled cardiac reoxygenation, as an adjunct to substrate-enhanced cardioplegia, has been shown to improve myocardial function and limit reperfusion injury when utilizing standardized hyperoxic cardiopulmonary bypass (CPB)" 03/01/1995 - "Efficacy of terminal warm blood cardioplegia against the reperfusion injury]" 10/01/2003 - "In the present study, we examined whether leukocyte depletion as an adjunct to terminal blood cardioplegia attenuates reperfusion injury" 07/01/2000 - "However, some studies suggest that activated neutrophils form blood cardioplegia can cause reperfusion injury" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Potassium
2.	crystalloid solutions
3.	Adenosine
4.	Calcium
5.	Adenosine Triphosphate (ATP)
6.	Oxygen
7.	Cardioplegic Solutions
8.	Creatine Kinase (Creatine Phosphokinase)
9.	Arginine (L-Arginine)
10.	Glucose (Dextrose)

Related Therapies and Procedures

1.	Cardiopulmonary Bypass (Heart-Lung Bypass)
2.	Transplants (Transplant)
3.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
4.	Extracorporeal Circulation
5.	Heart Transplantation (Grafting, Heart)

Best Treatments:
Research Summary Report
on Ischemia

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 2709 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>