Conductive Hearing Loss

Hearing loss due to interference with the mechanical reception or amplification of sound to the COCHLEA. The interference is in the outer or middle ear involving the EAR CANAL; TYMPANIC MEMBRANE; or EAR OSSICLES.

Also Known As:

Networked: 418 relevant articles (33 outcomes, 24 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hearing Loss (Hearing Impairment)
2.	Tinnitus
3.	Deafness (Deaf Mutism)
4.	Sensorineural Hearing Loss
5.	Otitis Media

Experts

1.	Rosowski, John J: 5 articles (03/2016 - 03/2003)
2.	Cremers, Cor W R J: 5 articles (01/2012 - 01/2002)
3.	Snik, Ad F M: 4 articles (01/2021 - 01/2002)
4.	Mylanus, Emmanuel A M: 4 articles (10/2020 - 01/2002)
5.	McKenna, Michael J: 4 articles (04/2018 - 03/2004)
6.	Ganaha, Akira: 3 articles (03/2022 - 04/2020)
7.	Tono, Tetsuya: 3 articles (03/2022 - 04/2020)
8.	Thomeer, Hans G X M: 3 articles (01/2020 - 11/2019)
9.	Cox, Matthew D: 3 articles (12/2017 - 03/2015)
10.	Dornhoffer, John L: 3 articles (12/2017 - 03/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Conductive Hearing Loss:

1.	TitaniumIBA 02/01/2014 - "BAHA implants have been shown to be effective in certain forms of conductive hearing loss, but the presence of the titanium abutment is responsible for sometimes severe skin reactions. " 03/01/2005 - "An earlier study of ossiculoplasty showed that titanium prostheses were effective in reducing conductive hearing loss. " 03/01/2015 - "Use of the titanium stapes FPP during TORP ossiculoplasty provides a statistically significant advantage in short-term PTA-ABG closure and a higher rate of successful rehabilitation of conductive hearing loss. " 01/01/2004 - "Successful rehabilitation (<or=20 dB pure-tone average air-bone gap) of conductive hearing loss was obtained in 70% of partial ossicular chain reconstructions and 44% of total ossicular chain reconstructions when titanium prostheses were used. " 04/01/2009 - "Thirty-eight patients with bilateral moderate to severe mixed or conductive hearing loss from COM without cholesteatoma and bilateral ossicular chain erosion (footplate residual) were alternately assigned to a titanium-TORP (T-TORP) and to RWI with the FMT of the Medel Vibrant Soundbridge (MVBS) located onto the RW niche. "
2.	Bone Cements (Bone Glue)IBA 02/01/2006 - "Bone cement ossiculoplasty offers cost-effective and significant improvement in conductive hearing loss. " 05/01/2005 - "Bone cement ossiculoplasty offers cost effective and significant improvement in conductive hearing loss."
3.	SolutionsIBA 07/01/2019 - "The ADHEAR system is a promising solution for children with conductive hearing loss or chronically draining ears." 01/01/2019 - "Based on our initial data, the ADHEAR seems to be a suitable alternative for patients who need a hearing solution for conductive hearing loss but for medical reasons cannot or do not want to undergo surgery for a passive BC implant." 01/01/2019 - "Together with a very low rate and minor nature of adverse events, it is the state-of-the-art solution for hearing rehabilitation in patients with mixed or conductive hearing loss up to a bone conduction threshold of 45 dB HL." 10/01/2010 - "Lateral semicircular canal fenestration for congenital conductive hearing loss: Solution for a dilemma." 01/01/2017 - "A custom 3D printed ossicular prosthesis is a viable solution for conductive hearing loss due to ossicular chain defects. "
4.	antineoplaston A10 (A 10)IBA 01/01/2020 - "Case two is a 10 year old female patient with conductive hearing loss. " 03/01/2007 - "Patients with conductive hearing loss who obtained at least a 10 dB improvement (at 1 and 2 kHz frequencies) in their bone conduction threshold post-operatively were included in the Carhart's notch group. " 09/01/2005 - "Four patients had more than a 10 dB deterioration in conductive hearing loss. " 07/01/2020 - "26 patients received audiology tests at 3 months after operation, 18 cases with normal hearing or mild conductive hearing loss preoperatively had normal hearing after operation, 2 cases with moderate conductive hearing loss had a 10-15 dB HL increase in air-bone gap after operation,hearing reconstructions surgery was not performed in 1 case of severe mixed hearing loss and 1 case of moderate conductive hearing loss due to serious damage in the middle ear structure, therefore no significant improvement in hearing in these two cases,four cases with extremely severe hearing loss before the operation had no hearing improvement, while nine cases did not provide the hearing results. "
5.	Adrenal Cortex Hormones (Corticosteroids)IBA 06/01/2010 - "The patients' symptoms, including conductive hearing loss, improved dramatically with reduction in lesion size after corticosteroid treatment." 01/01/2016 - "This role involves recognizing its clinical symptoms, distinguishing it from conductive hearing loss with the Weber tuning fork or the Rauch hum test, and urgent administration of high dose oral corticosteroids. "
6.	G(M1) GangliosideIBA 07/01/1995 - "The present investigation demonstrates the extent of a conductive loss caused by atresia and tests the hypothesis that GM1 ganglioside treatment will ameliorate the conductive hearing loss. " 07/01/1995 - "Auditory brainstem responses were recorded from four groups of seven mice each: two groups received daily subcutaneous injections of saline (one group had normal hearing; the other had a conductive hearing loss); the other two groups received daily subcutaneous injections of GM1 ganglioside (one group had normal hearing; the other had a conductive hearing loss). " 07/01/1995 - "Exogenous administration of GM1 ganglioside to CBA/J mice with a neonatal conductive hearing loss ameliorates the atrophy of spiral ganglion neurons, ventral cochlear nucleus neurons, and ventral cochlear nucleus volume. "
7.	adenosine 5'-(O-methylphosphate) (MEPA)IBA 02/01/2018 - "MeroGel) or cartilage as the MEPA resulted in improved hearing for patients with conductive hearing loss due to adhesive OM. "
8.	Silver Sulfadiazine (SSD)FDA LinkGeneric 07/01/2022 - "Twelve children were implanted: five BCI601 and seven BCI602 comprising of ten conductive hearing loss, and two single sided deaf SSD subjects. " 01/01/2021 - "The ABR results in our patient indicated the possibility that newborn hearing screening may not detect conductive hearing loss in patients with NOG-SSD. " 01/01/2021 - "We describe a dominant Japanese patient with progressive conductive hearing loss who was diagnosed with NOG-related symphalangism spectrum disorder (NOG-SSD), a spectrum of congenital stapes fixation syndromes caused by NOG mutations. " 10/01/2019 - "Nine SSD patients with different onset and period of hearing deprivation and 20 young adults with normal hearing and simulated conductive hearing loss as the control groups conducted speech perception in noise (SPIN) and Gap-In-Noise (GIN) tests. " 06/13/2022 - "16 patients with single-sided deafness (SSD) and mixed or conductive hearing loss who underwent Ponto implantation from December 2018 to September 2020 were enrolled in the study. "
9.	2- benzylidene- 3- (cyclohexylamino)- 2,3- dihydro- 1H- inden- 1- oneIBA 01/01/2018 - "The objective of this study is to quantify the effect of the Bone Conduction Implant (BCI) on sound localisation accuracy in subjects with conductive hearing loss (CHL). " 01/01/2018 - "Individuals with mixed/conductive hearing loss may benefit from a unilateral BCI in sound localisation." 07/31/2023 - "To assess and compare binaural benefits and subjective satisfaction of active bone conduction implant (BCI) in patients with bilateral conductive or mixed hearing loss fitted with bilateral BCI and patients with monaural conductive hearing loss fitted with monaural BCI. " 04/01/2017 - "The transcutaneous BCI is very well tolerated at 1-year follow up, improves audiometric thresholds and intelligibility for speech in quiet and noise, and gives satisfaction to both patients with mixed and conductive hearing loss and patients with SSD."
10.	Glass Ionomer CementsIBA 05/01/2013 - "Objective of this study is to compare glass ionomer cement application and incus interpositioning techniques in patients who have chronic otitis media, conductive hearing loss with intact tympanic membrane and who undergo hearing reconstruction of staged surgery using a retrospective chart review in the setting of Ministry of Health Ankara Training and Research Hospital ENT Clinic, Turkey. " 10/01/2017 - "To evaluate early hearing outcomes using glass ionomer cement to fix the Teflon piston prosthesis onto the long process of incus to minimize residual conductive hearing loss after stapedotomy. "

Therapies and Procedures

1.	Stapes Surgery (Stapedectomy) 01/01/2012 - "Independently of the patients being diagnosed with OI type I or IV and independently of the underlying OI genotype, beneficial results are obtained in the majority of OI patients undergoing primary or revision stapes surgery for reduction of conductive hearing loss components caused by stapes footplate fixation. " 12/01/2015 - "The temporal bone histopathology findings suggest that conductive hearing loss related to NOG mutation should be improved after stapedectomy; however, care must be taken in extrapolating to all patients with NOG mutations because there may be variability in the pathology, especially given the variability of NOG spectrum disorders." 04/01/2008 - "According to our study, simultaneous bilateral stapes surgery can be performed safely in selected patients with bilateral conductive hearing loss. " 01/01/2023 - "Among the functional failures of stapes surgery is recurrent conductive hearing loss, which can occur after a variable period of hearing improvement, from days/months up to many years after surgery. " 01/01/2023 - "Recurrence of conductive hearing loss after stapes surgery: a narrative review."
2.	Hearing Aids (Hearing Aid) 06/01/2015 - "We can confirm that both transcutaneous and percutaneous techniques are effective in the rehabilitation of conductive hearing loss when conventional hearing aids cannot be used. " 12/01/2021 - "This study included 35 patients (53 ears with an abnormal ear canal and severe conductive hearing loss) who were using CC hearing aids. " 05/01/2005 - "To study the effect of a bone-anchored hearing aid (BAHA) in patients with unilateral conductive hearing loss. " 08/01/1994 - "In the present study, aided thresholds were determined in 40 children and 30 adults with pure conductive hearing loss (bone-conduction thresholds of 20 dB HL or less) who were successfully fitted with hearing aids. " 10/01/2023 - "Thirteen patients (54%) had documented conductive hearing loss on audiological evaluation; with 11 (85%) requiring hearing aids. "
3.	Prostheses and Implants (Prosthesis) 04/01/2008 - "The study also suggests that, whilst stapedotomy piston prostheses are effective in the reversal of conductive hearing loss, they produce an insufficient pressure wave to elicit a myogenic response to sound. " 01/01/2020 - "This work represents a reference for the development of a new generation of middle ear prostheses with non-conventional topologies for fabrication via additive manufacturing technologies or ultraprecision machining in order to create patient-specific devices to recover from conductive hearing loss." 01/01/2014 - "Recurrent or persisting conductive hearing loss is commonly caused by prosthesis dislocation and adhesions in the oval window. " 10/01/2004 - "Exploratory tympanotomy is essential to identify congenital conductive hearing loss and wire prosthesis may provide a potential way for reconstruction of ossicular chain." 05/01/2000 - "However, thin-section computed tomography (CT) can help determine the type of prosthesis used for reconstruction and adequately assess for complications that may be causing postoperative conductive hearing loss. "
4.	Tympanoplasty 10/01/2001 - "A subpopulation of hearing-impaired patients has conductive hearing loss that cannot be improved by classic tympanoplasty. " 08/01/2022 - "Forty four patients between the age group 18-60 years undergoing type 1 revision tympanoplasty, with conductive hearing loss were enrolled.There" 04/01/2020 - "We performed tympanoplasty for a middle ear malformation with conductive hearing loss. " 07/01/2013 - "We present a case of persistent otorrhea and conductive hearing loss caused by myospherulosis in the middle ear following tympanoplasty. " 05/01/2013 - "Lateral graft tympanoplasty, the recommended treatment, is technically difficult and is plagued with blunting of the anterior sulcus and lateralization of the TM, both of which can lead to conductive hearing loss. "
5.	Endoscopes 04/07/2019 - "Objective: To explore the efficacy of ossiculoplasty surgery under oto-endoscope in patients of conductive hearing loss with intact tympanic membrane. " 04/07/2019 - "[A multi-center retrospective study of ossiculoplasty surgery under oto-endoscope in 45 cases of conductive hearing loss with intact tympanic membrane]." 05/01/2022 - "This study aims to compare results of tympanoplasty done with microscope vs endoscope in terms of graft take rate and improvement in conductive hearing loss. "