Hearing Disorders (Hearing Disorder)

01/01/2017 - "Antioxidants protect against hearing disorders induced by ototoxic agents or adverse health conditions; however, it is unknown whether the protective effects of antioxidants in hearing disorders are mediated by changing the expression of miRs. "
01/01/2017 - "A similar role of antioxidants in protecting against hearing disorders is put forward. "
01/01/2017 - "Therefore, it is proposed that a similar mechanism of protection by antioxidants against stress may be found in hearing disorders. "
01/01/2011 - "This review outlines the biologic concepts related to some auditory and vestibular conditions and details the current rationale for utilizing antioxidants for a spectrum of hearing disorders. "
02/01/2017 - "As results, a significant protection against cochlear toxic damage was demonstrated in patients who took the antioxidant supplement, which furthermore prevented the occurrence of hearing disorders and tinnitus. "

11/01/2011 - "It must be realized that despite the widespread use of glucocorticoids to treat hearing disorders, the molecular mechanisms underlying this treatment are not well characterized. "
04/01/2007 - "Glucocorticoids are widely used to treat different hearing disorders yet the exact mechanisms of glucocorticoid action on the inner ear are not known. "
05/01/2006 - "Glucocorticoids (GC) are widely used to treat different hearing disorders; yet the mechanisms of GC action on the inner ear are unknown. "
01/01/2019 - "Considering the well-established positive impact of chronotherapeutic approaches in the treatment of cardiovascular, asthma and cancer, an increased knowledge on the mechanisms where circadian, immune and glucocorticoids meet in the cochlea may improve current treatments against hearing disorders."
01/01/2018 - "Systemic corticosteroids have been the mainstay of treatment for various hearing disorders for more than 30 yr. Accordingly, numerous studies have described glucocorticoids (GCs) and stressors to be protective in the auditory organ against damage associated with a variety of health conditions, including noise exposure. "

12/15/2010 - "Alternative steroid treatments that minimize or eliminate these effects would significantly benefit therapeutic control of hearing disorders. "
10/01/1999 - "These positive results suggest the autoimmune mouse may be useful for studies of steroid-responsive mechanisms of the cochlea in autoimmune sensorineural hearing loss, as well as any hearing disorder in which steroid therapy is currently used."
11/01/2012 - "Specific misconceptions addressed are that steroid therapy is not effective, steroid-responsive hearing loss proves an underlying inflammatory problem in the ear, and steroids only have application to the hearing disorders listed below. "
11/01/1999 - "This could apply to autoimmune sensorineural hearing loss, as well as any hearing disorder for which steroid therapy is recommended."
12/15/2010 - "This efficacy of combined steroids at low doses suggests the potential for reducing the side effects of glucocorticoids in the therapeutic control of hearing disorders."

01/01/2018 - "Systemic corticosteroids have been the mainstay of treatment for various hearing disorders for more than 30 yr. Accordingly, numerous studies have described glucocorticoids (GCs) and stressors to be protective in the auditory organ against damage associated with a variety of health conditions, including noise exposure. "

02/01/1989 - "Recent advances in plastic and middle ear surgery have improved the prognosis of patients suffering from congenital hearing disorders. "
07/01/2001 - "This has prompted research to determine whether such plastic changes occur in adults and children with hearing disorders. "
01/01/2012 - "The pathophysiology underlying tinnitus, a hearing disorder characterized by the chronic perception of phantom sound, has been related to aberrant plastic reorganization of the central auditory system. "
01/01/2018 - "Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as tinnitus and hyperacusis. "

04/01/1996 - "The potency of NT-3 in protecting spiral ganglion neurons from degenerating suggests that neurotrophins may be useful for the treatment of hearing disorders."
07/01/2002 - "The potency of NT-3 in SGN neuroprotection suggests that in vivo neurotrophin-based gene therapy is a promising preventative treatment for chemical-induced hearing disorders, and potentially for hearing degeneration due to normal aging."
06/01/2001 - "The potency of NT-3 in protecting spiral ganglion neurons from degeneration suggests that in vivo neurotrophin-based gene therapy may be useful for the prevention and/or treatment of hearing disorders."
01/01/2019 - "Neurotrophins and their mimetics are potential treatments for hearing disorders because of their trophic effects on spiral ganglion neurons (SGNs) whose connections to hair cells may be compromised in many forms of hearing loss. "

01/01/2023 - "The results on a standard Audiology dataset show that the proposed method produces 96.50% accuracy with optimal solution compared to classical SVM, which signifies the proposed method is effective in handling high dimensional data for hearing disorder prediction."
06/01/2022 - "Unveiling the mechanism of miR-122-5p in the mediation of forkhead box O3 (FOXO3) in regards to cochlear hair cell damage provides an effective solution for the treatment of ear hearing disorders. "
01/01/1985 - "[Mediation and solution of interpersonal problems in a family composed of an aged couple with hearing disorders and persecution complexes, their son and his wife]."

01/01/2020 - "Penicillins have never been associated with any form of hearing disorders. "
05/15/1987 - "Hearing disorder and choked disc improved during the therapy with penicillin. "

12/01/2020 - "Coenzyme Q10 is an example of a poorly water-soluble compound with low bioavailability, and significant inter-individual variation after oral administration; limiting its optimum efficacy, as a powerful antioxidant with significant promise in treating hearing disorders. "

04/01/2002 - "In what is about to become the postgenomic era, the study of the proteins encoded by these genes will advance our understanding of auditory development and function and lead to innovative approaches toward the treatment of patients with hearing disorders."
01/01/2016 - "We describe here, a protocol for detecting excitatory and inhibitory marker proteins along the ascending auditory pathway, which could be a useful tool for detecting changes in auditory signal processing during various forms of hearing disorders. "
03/02/2007 - "It may be hypothesized that abnormal sarcomeric proteins present in the muscular structures of the inner ear in HCM are possibly responsible for the hearing disorders in these patients, and that this is not merely a neurological defect."
01/01/2005 - "Mutations of the human gene encoding transmembrane channel-like protein (TMC)1 cause dominant and recessive nonsyndromic hearing disorders, suggesting that this protein plays an important role in the inner ear. "
09/01/2002 - "No obvious morphological abnormalities were detected in Klotho mice, although no expression of Klotho protein was detected, and there was an apparent hearing disorder. "

04/01/2017 - "Only with individualized therapy can the success of treating hearing disorders be significantly improved."
10/01/2010 - "Sufficient insight into many homeostatic hearing disorders has now been attained to usher in a new era of better therapies and improved clinical outcomes."
01/01/2018 - "The findings obtained indicate that rehabilitation therapy based on the manipulation of auditory inputs is an effective and safe approach for hearing disorders. "
01/01/2005 - "From a critical analysis - particularly of the clinical studies presented - conclusions are drawn for the therapy of hearing disorders in the future."
04/01/1948 - "Hearing disorders; a study of a new medical therapy."

10/01/2014 - "The quality of life was worse in individuals with hearing disorders, as measured with the EuroQol EQ-VAS (60.93 ± 1.38 vs. 71.75 ± 0.45, p< 0.0001), but it improved among those who used hearing aids as compared to those who did not use them (59.59 ± 1.52, p<0.01). "
11/01/1995 - "Hearing aid acceptance was found to be 63% with a measurable hearing improvement in 59% of the patients, even in the presence of severe hearing disorders. "
01/01/2023 - "This study investigated the prevalence of hearing disorders and the actual provision with hearing aids. "
07/29/2023 - "Vocants might be relevant in the early diagnosis of hearing disorders and assessments of the effectiveness of, or adjustments required to, hearing aids."
07/01/2019 - " should undergo routine hearing screenings in order to detect hearing disorders as soon as possible so that hearing aids can be prescribed at an early stage. "

01/01/1974 - "[Remission of uremic hearing disorders following successful kidney transplantation]."
01/01/2022 - "It is not known whether hearing disorders improves with kidney transplantation. "

12/01/2020 - "Coenzyme Q10 is an example of a poorly water-soluble compound with low bioavailability, and significant inter-individual variation after oral administration; limiting its optimum efficacy, as a powerful antioxidant with significant promise in treating hearing disorders. "

01/01/1985 - "The results of our studies show that hyperbaric oxygen therapy shortens the course of healing with respect to high-pitch perception dysacusis. "
11/01/1990 - "[Effect and effectiveness of hyperbaric oxygen therapy in chronic hearing disorders. "
07/01/1989 - "[Our experience in the hyperbaric oxygenation treatment of patients with acute sensorineural hearing disorder of vascular etiology]."
01/01/2007 - "Acupuncture combined with hyperbaric oxygenation can overall and synchronously rehabilitate sense and motor functions, significantly improve balance disturbance in the patient of cerebral infarction, with unique therapeutic effect on dysopia and dysacusis for the patient of cerebral infarction at the early stage."