Headache (Headaches)

7914  relevant articles (642 outcomes, 754 trials/studies) found for this Disease

Headaches; Cephalalgia; Hemicrania; Throbbing Headache; Head Pains; Bilateral Headache; Cephalodynia; Cranial Pain; Generalized Headache; Head Pain; Ocular Headache; Orthostatic Headache; Periorbital Headache; Retro-Ocular Headache; Sharp Headache; Unilateral Headache; Vertex Headache; Bilateral Headaches; Cephalalgias; Cephalgias; Cephalodynias; Cranial Pains; Generalized Headaches; Headache, Bilateral; Headache, Generalized; Headache, Ocular; Headache, Orthostatic; Headache, Periorbital; Headache, Retro-Ocular; Headache, Sharp; Headache, Throbbing; Headache, Unilateral; Headache, Vertex; Headaches, Bilateral; Headaches, Generalized; Headaches, Ocular; Headaches, Orthostatic; Headaches, Periorbital; Headaches, Retro-Ocular; Headaches, Sharp; Headaches, Throbbing; Headaches, Unilateral; Headaches, Vertex; Ocular Headaches; Orthostatic Headaches; Pain, Cranial; Pain, Head; Pains, Cranial; Pains, Head; Periorbital Headaches; Retro Ocular Headache; Retro-Ocular Headaches; Sharp Headaches; Throbbing Headaches; Unilateral Headaches; Vertex Headaches; Cephalgia

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Migraine Disorders (Migraine)
2.	Pain (Aches)
3.	Headache (Headaches)
4.	Nausea
5.	Dizziness (Lightheadedness)
828 Diseases and 4975 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Olesen, J: 15 articles (11/2006 - 06/2000)
2.	Goadsby, P J: 7 articles (07/2007 - 03/2003)
3.	Silberstein, Stephen D: 6 articles (01/2007 - 06/2002)
4.	Nappi, G: 5 articles (04/2008 - 02/2004)
5.	Stovner, L J: 5 articles (01/2008 - 09/2004)
6.	Mauskop, Alexander: 5 articles (05/2007 - 05/2002)
7.	Silberstein, S D: 5 articles (11/2001 - 01/2000)
8.	Olesen, Jes: 4 articles (09/2008 - 09/2002)
9.	Lipton, R B: 4 articles (05/2008 - 11/2000)
10.	Diener, H C: 4 articles (02/2008 - 01/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Headache:

1.	Sumatriptan (Imigran)FDA Link 04/01/1993 - "In addition, they examine the initial efficacy of treatment and the mechanism of recurrence of headache within 24 hours, which is the most important drawback of sumatriptan in clinical practice, next to its possible cardiac side effects." 06/01/1999 - "The headache resolved completely after a subcutaneous injection of sumatriptan." 01/01/2005 - "A single dose of sumatriptan 10 mg (approved European dosage) was significantly more effective than placebo in achieving headache relief at 1 hour post-dose in a well designed study" 07/01/1994 - "In both studies, headache severity had significantly improved at 120 min after doses of 10-40 mg sumatriptan compared to placebo (P < 0.05) and the greatest efficacy rates were obtained with 20 mg sumatriptan" 04/01/2008 - "We describe an adolescent with acute posttraumatic headache that did not respond to several initial medications but had rapid and sustained improvement in headache and associated migrainous features with subcutaneous sumatriptan." Get all the results and reference details, order at left...
2.	Pain-FreeIBA 01/01/2002 - "The drug is significantly more effective than placebo as measured by a number of parameters including 2-hour headache response and pain-free response rates" 01/01/2002 - "The drug is significantly more effective than placebo as measured by a number of parameters including 2-hour headache response and pain-free response rates" 08/01/1999 - "The drug is significantly more effective than placebo as measured by a number of parameters including 2-hour headache response rates and pain-free response rates" 06/01/2005 - "A total of 16 subjects (76.2%) had their headache scores improved by 50% or more; nine (42.9%) were pain free at the last follow-up" 09/01/2004 - "HC exists in two temporal subtypes, a continuous form in which headaches persist continuously without remission periods, and a less common remitting form in which bouts of continuous headaches are separated by pain-free remissions" Get all the results and reference details, order at left...
3.	Analgesics (Analgesic Drugs)IBA 08/01/2008 - "Whereas only half of children received abortive medications for these headaches, simple analgesics were effective in most cases" 06/01/1990 - "The headache was more improved in the physiotherapy group, and there was a marked reduction in the intake of analgesics" 01/01/2006 - "The treatment resulted in significant reduction of frequency, duration and intensity of headache, with a 2-fold decrease in analgesics used" 11/23/1985 - "Headaches were more common in patients with active patches but were relieved by simple analgesics." 09/01/2005 - "CONCLUSIONS: These results demonstrate the efficacy of withdrawal treatment in difficult cases suffering from analgesics abuse headache" Get all the results and reference details, order at left...
4.	zolmitriptan (Zomig)FDA Link 10/01/2005 - "In phase one of the REALIZE study, zolmitriptan nasal spray demonstrated a significant headache response from 10 min post-dose and total symptom relief from 30 min post-dose" 01/01/2006 - "RESULTS: There was no statistically significant improvement between zolmitriptan 10 mg (2 x 5 mg tablet) and placebo for the primary efficacy variable, headache response at 2 hours, nor any of the secondary variables tested" 03/01/2002 - "Headache relief following zolmitriptan 2.5 mg (63%) was significantly greater than with placebo (22%) at 2 h post-dose (primary endpoint; P < 0.0001)" 06/01/1996 - "Plasma 311C90 concentrations were generally higher in those patients who responded to treatment with 311C90 in the plasma, but there was one patient with no quantifiable 311C90 in the plasma whose headache improved" 11/01/1997 - "In patients with persistent or recurrent headache, a second zolmitriptan dose effectively treated both headache and nonheadache symptoms" Get all the results and reference details, order at left...
5.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/01/1999 - "Although acetylsalicylic acid (ASA) is one of the most commonly administered drugs in the treatment of acute headaches, the sites of its action and the mechanisms of its therapeutic efficacy are still unclear" 06/01/2001 - "OBJECTIVE: To evaluate the efficacy of aspirin for headache when exercising during acute high-altitude exposure" 06/01/2001 - "Effects of aspirin during exercise on the incidence of high-altitude headache: a randomized, double-blind, placebo-controlled trial." 04/04/1998 - "Aspirin for prophylaxis against headache at high altitudes: randomised, double blind, placebo controlled trial." 08/30/1983 - "We report some preliminary results of a study carried out in ten patients observed during headache attack and concerning particularly the plasma values of beta-ELI after acetylsalicylic acid (lysini acetylsalicylas: i.v. 1.8 g) administration" Get all the results and reference details, order at left...
6.	Indomethacin (Indometacin)FDA LinkGeneric 01/01/2006 - "RESULTS: All patients responded favorably to indomethacin, with rapid near-complete or complete resolution of headache and autonomic symptoms, and treatment was initiated as early as possible" 05/01/1991 - "Benign headache associated with sexual activity has been successfully treated with indomethacin and beta-blockers" 11/01/1983 - "A patient with long standing sustained unilateral headache ("background vascular") and occasional multiple jabs received prompt and lasting relief from indomethacin" 02/01/1978 - "Treatment with indomethacin eliminated these headaches" 09/01/2002 - "Some patients are able to stop indomethacin without headache recurrence, highlighting the importance of a trial of discontinuation" Get all the results and reference details, order at left...
7.	Amitriptyline (Elavil)FDA LinkGeneric 03/01/2004 - "In contrast, amitriptyline was most effective in reduction of headache" 03/01/2006 - "For children with frequent headache, the antidepressant amitriptyline might be beneficial for prophylaxis, although no placebo-controlled studies have been done" 02/01/2006 - "The combination therapy was effective since the first month of treatment, with a significant reduction of the headache, greater than one obtained with amitriptyline alone, in terms of frequency (-52.3% vs. -40.7%), intensity (-59.51% vs. -20.39%) and duration (-53.17% vs. -36.16%)" 11/01/1994 - "In the amitriptyline group, a significant reduction in daily headache duration was already found in the 3rd week of treatment, while in the placebo group no significant changes in headache duration were to be seen" 10/01/1994 - "In the amitriptyline group, a significant reduction in daily headache duration was already found in the third week of treatment, while in the placebo group no significant changes in headache duration were to be seen" Get all the results and reference details, order at left...
8.	Ibuprofen (Motrin)FDA LinkGeneric 05/01/2003 - "Ibuprofen was significantly more effective than placebo in reducing the severity of ECT-induced headache (p =.007)" 05/01/2003 - "Ibuprofen was significantly more effective than placebo in preventing the onset of headache post-ECT (p =.022)" 01/01/1994 - "The results suggest that ibuprofen is a safe and effective treatment for high altitude headache." 05/01/2003 - "The objective of this study was to determine whether pretreatment with ibuprofen would prevent the onset or decrease the severity of headache that occurs after ECT" 02/01/2007 - "Explanatory analyses revealed worsening of headache already in the third week of treatment with ibuprofen alone" Get all the results and reference details, order at left...
9.	Tryptamines (Triptans)IBA 02/01/2002 - "RESULTS: Important pharmacologic, pharmacokinetic, and clinical differences exist among those drugs, but the tolerability profile of the newer triptans is very good, and they provide rapid relief from headache and sustained duration of effect" 09/01/2006 - "RESULTS: The group treated with TPM had a significant reduction in the number of days with headache (P < 0.0001 vs placebo) and in the mean amount of acute medication taken (P < 0.0001 vs placebo); all triptans were superior to placebo; there were no significant differences between different triptans; the analgesic effect of triptans increased throughout the trial" 09/01/2006 - "We also studied the efficacy of single triptans available in Italy in interrupting headache crises during preventive treatment" 01/01/2005 - "CONCLUSION: Despite an increase in headache consultation rates and in use of prescription medication and triptans, no improvement in work absence rates was observed" 01/01/2002 - "Headache recurrence as a criterion for assessing efficacy of triptans: a perspective." Get all the results and reference details, order at left...
10.	Acetaminophen (Paracetamol)FDA LinkGeneric 05/01/1999 - "The only side effects noted were severe headaches after gammaglobulin infusions which responded well to oral paracetamol" 02/01/1991 - "The present data suggest that the proposed posture-related changes in volume of distribution do not exist, and that there is no pharmacokinetic basis for a headache being relieved by taking paracetamol and lying down." 09/28/2004 - "Acetaminophen was no more effective than placebo in the acute and preemptive treatment of these headaches." 12/11/2000 - "RESULTS: The headache response rate 2 hours after dosing was 57.8% in the acetaminophen group and 38.7% in the placebo group (P =.002)" 09/01/2000 - "Efficacy was measured by visual analog scale, the number of headache-free days, the daily duration of headache, and the use of paracetamol" Get all the results and reference details, order at left...
1767 Drugs and Important Bio-Agents and 6731 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Biofeedback (Psychology) (Biofeedback) 12/01/2007 - "CBT was highly effective, with an average reduction in headaches from pre- to posttreatment of 68%, compared with 56% for biofeedback, and 20% for the control condition" 10/01/1996 - "We conclude that behavioural treatment strategies are effective in the management of childhood headaches, although most of the research support appears to be limited to relaxation training and biofeedback" 07/01/1982 - "Biofeedback has proven effective in treatment of vascular and muscle contraction headache" 01/01/2000 - "Results showed that both children and adults reported substantial improvements in headache activity with TBF and EMG biofeedback treatment (Ms ranged from 34% to 81%), but children showed significantly greater improvement than adults" 03/01/1980 - "Although biofeedback and pseudotherapy were rated as equally credible treatments, only the headache activity of the biofeedback group was significantly improved following treatment" Get all the results and reference details, order at left...
2.	Aftercare (After-Treatment) 04/01/2007 - "After treatment with epidural autolongous blood patch, her headache resolved completely" 05/01/2008 - "Patients improved significantly after treatment intervention, as days of headache per month and medications/month decreased from baseline to follow up" 10/01/2001 - "Mean headache indices improved significantly after treatment, both in the treatment group and in the placebo group, but the difference between the two groups was insignificant" 03/01/2008 - "Immediately after treatment, his hearing improved and his headache resolved." 08/01/2007 - "All of the patients were free of headache,improvement in vision and ocular motility after treatment" Get all the results and reference details, order at left...
3.	Bed Rest (Bedrest) 12/01/2004 - "His headache improved 2 weeks after the operation with strict bed rest" 12/01/2004 - "Initial CT scan showed normal brain structure, and his headache improved with bed rest in a few days" 09/01/2003 - "Eight days later headache improved with bed rest and hydration" 07/01/1996 - "Bed rest was frequently voluntary (as opposed to being enforced on medical orders) since many patients only gained relief from their headache when supine" 07/01/1989 - "The headache improved after about 3 hours of bed rest" Get all the results and reference details, order at left...
4.	Drug Therapy (Chemotherapy) 05/01/2008 - "The efficiency of drug therapy was evaluated by the outcome scale based on the patients' headache diaries (outcome graded as improved, unchanged or worsened)" 09/01/2005 - "In this study we evaluated the incidence of headache in young people, examined associated factors and described the drug therapy used" 04/01/1997 - "While studies evaluating the role of headache on health-related quality of life and healthcare economics are starting to appear in the medical literature, the effect of pharmacotherapy in improving quality of life is only beginning to be studied" 03/01/1963 - "Studies in the pharmacotherapy of headache." 09/01/2008 - "She complained of headache during the course of chemotherapy, for which CSF examination was undertaken" Get all the results and reference details, order at left...
5.	Spinal Manipulation 10/01/2005 - "Conversely, spinal manipulation obtained no more than limited evidence (level 3) in reducing headache frequency, as it was analyzed only in one study with positive (+) results" 10/01/2002 - "Despite claims that spinal manipulation is an effective treatment for headache, the data available to date do not support such definitive conclusions" 03/01/2006 - "Randomized controlled trials in which spinal manipulation and/or mobilization had been used for TTH, CeH, and M published in a peer-reviewed journal as full text, and with at least 1 clinically relevant outcome measure (ie, headache intensity, duration, or frequency) were reviewed" 08/01/2004 - "Multivariate analysis showed that upper cervical manipulation (OR: 3.20; 95%CI: 1.89-7.77), use of medication (OR: 2.20; 95%CI: 1.31-3.69), gender (OR: 1.66; 95%CI: 1.01-2.75) and age (OR: 1.02; 95%CI: 1.00-1.05) were independent predictors of headache after spinal manipulation" 10/01/1998 - "Spinal manipulation is a common alternative therapy for headaches, but its efficacy compared with standard medical therapies is unknown" Get all the results and reference details, order at left...
251 Therapies and Procedures and 1509 more articles analyzed in the Full Patient-Physician Summary Report, order at left...