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Guanethidine

An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Also Known As:
((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine; Guanethidine Monosulfate; Guanethidine Sulfate; Guanethidine Sulfate (1:1); Guanethidine Sulfate (1:2); Guanethidine Sulfate (2:1); Guanethidine Sulfate (2:1), 14C-Labeled; Ismelin; Isobarin; Octadine; Oktadin; Monosulfate, Guanethidine; Sulfate, Guanethidine; Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
Networked: 618 relevant articles (33 outcomes, 55 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. He, Wei: 2 articles (07/2022 - 10/2019)
2. Ribeiro-da-Silva, Alfredo: 2 articles (09/2015 - 06/2013)
3. Paraskevas, Kosmas I: 2 articles (09/2006 - 07/2005)
4. Samara, Maria: 2 articles (09/2006 - 07/2005)
5. Chen, Li-Zhen: 1 article (07/2022)
6. Chen, Wei: 1 article (07/2022)
7. Jing, Xiang-Hong: 1 article (07/2022)
8. Li, Heng-Cong: 1 article (07/2022)
9. Liu, Yi-Han: 1 article (07/2022)
10. Su, Yang-Shuai: 1 article (07/2022)

Related Diseases

1. Pain (Aches)
2. Open-Angle Glaucoma (Glaucoma, Open Angle)
3. Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome)
4. Hypertension (High Blood Pressure)
5. Hyperalgesia

Related Drugs and Biologics

1. Epinephrine (Adrenaline)
2. Sympatholytics
3. Phentolamine (Z-Max)
4. Lidocaine (Xylocaine)
5. Guanethidine
6. Methylprednisolone
7. Methyldopa (Aldomet)
8. Ophthalmic Solutions (Eye Drops)
9. Reserpine (Serpasil)
10. Clonidine (ST 155)

Related Therapies and Procedures

1. Sympathectomy (Sympathectomies)
2. Therapeutics
3. Ligation
4. Chemical Sympathectomy
5. Denervation