Giant Cell Granuloma (Peripheral Giant Cell Granuloma)

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101 relevant articles (4 outcomes, 5 trials/studies) found for this Disease

Description: A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.

Also Known As:

Peripheral Giant Cell Granuloma; Giant Cell Epulis; Granuloma, Giant Cell; Epulides, Giant Cell; Giant Cell Epulides; Giant Cell Granulomas; Granulomas, Giant Cell; Epulis, Giant Cell; Granuloma, Giant Cell Reparative

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 87

Jaw Diseases: 7

Giant Cell Granuloma: 101

Stomatognathic Diseases: 273

Mouth Diseases: 56

Periodontal Diseases: 3754

Gingival Diseases: 75

Giant Cell Granuloma: 101

Jaw Diseases: 7

Giant Cell Granuloma: 101

Signs and Symptoms Pathological Conditions

Pathologic Processes: 2442

Granuloma: 6615

Giant Cell Granuloma: 101

Related Diseases

1.	Inflammation
2.	Xerostomia
3.	Foreign Bodies (Foreign Body)
4.	Neoplasms (Cancer)
5.	Giant Cell Tumors (Giant Cell Tumor)

Experts

1.	van den Akker, H P: 2 articles (09/2006 - 09/2006)
2.	van den Berg, H: 2 articles (09/2006 - 09/2006)
3.	de Lange, J: 2 articles (09/2006 - 09/2006)
4.	Lee, Heeje: 1 article (04/2008)
5.	Ercoli, Carlo: 1 article (04/2008)
6.	Palermo, Matthew: 1 article (04/2008)
7.	Coniglio, John U: 1 article (04/2008)
8.	Fantuzzo, Joseph J: 1 article (04/2008)
9.	Girotto, John A: 1 article (04/2008)
10.	Redeker, Egbert J W: 1 article (09/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Giant Cell Granuloma:

1.	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 04/01/1993 - "Aggressive central giant cell granulomas may be eliminated by administering human calcitonin 0.5 mg (100 iu) deep subcutaneously for 1 year. " 09/01/2006 - "Calcitonin therapy in central giant cell granuloma of the jaw: a randomized double-blind placebo-controlled study." 06/01/2009 - "OBJECTIVES: The aim was to evaluate the effectiveness of the long-term administration of intranasal calcitonin spray for the treatment of central giant cell granuloma (CGCG) in a retrospective case study. " 01/01/2009 - "However, we included and analysed one RCT with unclear risk of bias, evaluating the effects of calcitonin versus placebo for central giant cell granuloma of the jaws. " 07/01/2008 - "This paper reports four cases of central giant cell granuloma (CGCG) treated with calcitonin, attesting the efficacy and safety of its use as the chosen therapy for large CGCG. " Order ALL the reference details at left...
2.	FumaratesIBA 01/01/2002 - "Successful therapy of annular elastolytic giant cell granuloma with fumaric acid esters." Order ALL the reference details at left...
3.	Dapsone FDA Link 05/01/1997 - "Anti-oxidative therapy with oral dapsone improved HCV antibody positive annular elastolytic giant cell granuloma." Order ALL the reference details at left...
4.	Estrogens (Estrogen)FDA Link 07/01/1995 - "Estrogen receptor immunoreactivity was negative in all cases of central giant cell granulomas. " 12/01/1987 - "Recurrent giant cell granuloma occurring in the mandible of a patient on high dose estrogen therapy for the treatment of Sotos' syndrome." 06/01/1998 - "In this study, the presence of estrogen and progesterone receptors in 26 peripheral giant cell granuloma cases were studied utilizing the immunoperoxidase technique. " 06/01/1998 - "It was concluded that the cells forming peripheral giant cell granuloma are potential targets for estrogens and that these lesions might be conditioned by sex hormones." 06/01/1998 - "Estrogen and progesterone receptors in the peripheral giant cell granulomas of the oral cavity." Order ALL the reference details at left...
5.	Polytetrafluoroethylene (Teflon)FDA Link 11/01/1995 - "Histologically, evidence of a Teflon fiber-induced giant cell granuloma was identified. " 01/01/1989 - "The study showed that teflon was not an absolutely inert substance, it produced inflammation as giant cell granuloma of foreign bodies. " Order ALL the reference details at left...
6.	Progesterone Receptors (Progesterone Receptor)IBA 06/01/1998 - "In this study, the presence of estrogen and progesterone receptors in 26 peripheral giant cell granuloma cases were studied utilizing the immunoperoxidase technique. " 06/01/1998 - "Estrogen and progesterone receptors in the peripheral giant cell granulomas of the oral cavity." Order ALL the reference details at left...
7.	Levanol Fast Cyanine 5RNIBA 10/01/1989 - "In the present study, myofibroblasts were found in peripheral giant cell granuloma (PGCG) using the TP-Levanol fast cyanine 5RN histochemical procedure and electron microscopy. " Order ALL the reference details at left...
8.	Dental Implants (Dental Implant)IBA 10/01/2008 - "Peripheral giant cell granuloma associated with a dental implant. " 05/01/2007 - "This report discusses the management of a 21-year-old male who developed a peripheral giant cell granuloma (PGCG) associated with dental implant therapy, and reviews 4 previously reported cases of PGCGs developing in association with dental implant treatment. " 05/01/2007 - "An analysis of peripheral giant cell granuloma associated with dental implant treatment." 05/01/2007 - "Recurrent central giant cell granuloma in the mandible: surgical treatment and dental implant restoration." 03/01/2004 - "Peripheral giant cell granuloma associated with a dental implant." Order ALL the reference details at left...
9.	ParaffinIBA 04/01/2008 - "Immunohistochemistry was used to evaluate p63 expression in paraffin embedded sections of giant cell tumor of bone and in tumors containing multinucleated giant cells, including: giant cell tumor of tendon sheath, pigmented villonodular synovitis, aneurysmal bone cyst, chondroblastoma, and central giant cell granuloma. " 06/01/1999 - "Epulides were fixed in alcohol, paraffin embedded, and stained with haematoxyilin eosin, thereafter epulides were histopathologically classified as granulomatous epulides, fibrous epulides and giant cell epulides. " 03/01/2004 - "METHODS: Formalin-fixed, paraffin-embedded tissue from 29 cases of central giant cell granuloma was assessed for the expression of cyclin D1, cyclin B1, and MIB-1 (Ki-67) using immunohistochemistry. " 05/01/1996 - "Immunohistochemical investigation of PCNA and Ki-67, two diverse nuclear proteins essential to the cell cycle, was undertaken in archival, formalin-fixed and paraffin-embedded specimens of giant cell fibroma (GCF) and peripheral giant cell granuloma (PGCG++). " 10/01/1992 - "Antibodies to XIIIa, CD34, S-100 protein, and macrophage antigen (MAC 387) were tested on formalin-fixed, paraffin-embedded tissue sections from normal mucosa, peripheral fibroma (PF), peripheral ossifying fibroma (POF), peripheral giant cell granuloma (PGCG), pyogenic granuloma (PG), lymphangioma (La), benign fibrous histiocytoma (BFH), idiopathic histiocytosis (IH), angiofibroma (Af) using an ABC immunoperoxidase technique. " Order ALL the reference details at left...
10.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2009 - "The use of corticosteroids in the management of central giant cell granuloma is also demonstrated." 02/01/2002 - "Intralesional corticosteroids as an alternative treatment for central giant cell granuloma." 12/01/1994 - "Local injection of corticosteroids for central giant cell granuloma. " 12/01/1994 - "A case of central giant cell granuloma of the mandible is reported that was successfully treated with intralesional injection of corticosteroids." 11/01/2001 - "The giant cell granuloma of the jaws is a benign osteolytic lesion that may be treated by curettage, intralesional corticosteroids, or calcitonin. " Order ALL the reference details at left...

Therapies and Procedures

1.	Cryotherapy (Therapy, Cold) 01/01/2005 - "The article reports the case of central giant cell granuloma, affecting the anterior region maxillary of a child, whom a conservative treatment, with cryotherapy, helped the preservation of anterior permanent teeth germs." Order ALL the reference details at left...
2.	Oral Hygiene (Dental Hygiene) 05/01/1997 - "CONCLUSIONS: Findings from this study suggest that patients with large (> 2 cm) peripheral giant cell granuloma lesions are more likely to be women with lower oral hygiene scores and xerostomia. " Order ALL the reference details at left...
3.	Curettage 01/01/2006 - "It is concluded that thorough curettage is a satisfactory method for the treatment of non-aggressive and aggressive central giant cell granuloma of the maxilla, with a low recurrence rate and favorable postoperative outcome." 04/01/2003 - "Surgical curettage of these large central giant cell granulomas gives mulilations of the jaws and loss of teeth and tooth germs. " 04/01/1994 - "Only one patient with maxillary giant cell granuloma who underwent curettage had regrowth of what is suspected to have been residual disease. " 07/01/1987 - "An extensive giant cell granuloma of the mandible was treated by curettage rather than segmental resection." 01/01/1981 - "Surgical excision with curettage of the underlying bone is the accepted method of treatment for the peripheral giant cell granuloma. " Order ALL the reference details at left...
4.	Transplants (Transplant) 01/01/1986 - "Peripheral giant cell granuloma: a case history utilizing a free gingival graft." 04/01/2008 - "Oral rehabilitation of a 12-year-old patient diagnosed with a central giant cell granuloma using a fibula graft and an implant-supported prosthesis: a clinical report." 04/01/2009 - "Distraction osteogenesis of iliac bone graft as a reconstruction after central giant cell granuloma curettage." Order ALL the reference details at left...
5.	Intralesional Injections 02/01/2005 - "A recurrent central giant cell granuloma in a 14-year-old girl in the anterior region of the mandible was treated successfully by intralesional injection of corticosteroid." 12/01/2000 - "Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids." 12/01/1994 - "A case of central giant cell granuloma of the mandible is reported that was successfully treated with intralesional injection of corticosteroids." Order ALL the reference details at left...

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