|4.||Sarcoidosis (Schaumann Disease)
|1.||Sandor, Matyas: 16 articles (02/2015 - 05/2002)|
|2.||Flynn, JoAnne L: 15 articles (08/2015 - 11/2002)|
|3.||Chensue, Stephen W: 15 articles (01/2013 - 06/2002)|
|4.||Kirschner, Denise E: 14 articles (02/2015 - 07/2005)|
|5.||Kunkel, Steven L: 14 articles (01/2011 - 07/2002)|
|6.||Friedland, Jon S: 11 articles (08/2015 - 11/2003)|
|7.||Shkurupiy, V A: 11 articles (04/2014 - 12/2008)|
|8.||Orme, Ian M: 11 articles (02/2012 - 11/2002)|
|9.||Actor, Jeffrey K: 11 articles (01/2011 - 01/2002)|
|10.||Wynn, Thomas A: 11 articles (04/2010 - 01/2003)|
11/01/2011 - "Postoperative magnetic resonance imaging showed a significant reduction in the size of the cholesterol granuloma and a stable hearing threshold."
02/01/2007 - "Magnetic resonance imaging is useful for differential diagnosis, and endoscopic surgery is effective for the management of cholesterol granuloma arising in the ethomoid sinus."
01/01/2000 - "Large cholesterol granulomas of the petrous apex can be effectively treated through a keyhole middle fossa approach. "
07/01/2013 - "Trans-sphenoid sinus clivus endoscopic management of petrous apex cholesterol granuloma is effective and safe. "
02/01/2008 - "We feel that the endoscopic transsphenoidal approach is a safe and effective way to access cholesterol granulomas of the petrous apex."
06/01/1978 - "However, when patients in stages IIIB and IV were eliminated and patients in stages I, II, and IIIA examined separately, a positive skin test response to one or more antigens was elicited in 85.7% of patients with granulomas, while a markedly decreased-dose dependent response was observed in patients without granulomas. "
01/01/1984 - "These experiments demonstrate the dependence of the granulomatous reaction on T cell-mediated events, as well as the potential therapeutic efficacy of an antigen-specific suppressor T cell factor and a hybridoma T cell product in limiting antigen-specific granuloma formation in vivo."
12/01/2015 - "As the antigen persists and cannot be eliminated, the ongoing immune reaction results in granuloma formation and remodeling of the lung. "
01/01/2012 - "Finally, mice immunized with nanoparticles associated with the antigen SmRho plus CpG had 38% of the granuloma area reduced and also presented 48% of protection against of S. "
07/01/1999 - "The clearance of tubercle bacilli & mycobacterial antigen vis a vis the granuloma in different organs of guinea pigs."
01/01/2007 - "VIP treatment was very effective in diminishing worm fecundity, hepatic granuloma size and number by about 54%, 75% and 51%, respectively, and reducing liver collagen content. "
12/01/2005 - "A significant decrease in the number and size of granulomas with significant reduction in the collagen content deposition in portal tracts and around central veins was detected when compared to G.III (infected nontreated mice). "
08/01/1987 - "The mean diameter of lung granulomas induced by collagen-coupled beads in infected mice was significantly greater than the diameter of granulomas around either collagen beads in uninfected mice or uncoated beads in infected mice. "
05/01/2011 - "In the SIL-cell group, the fraction area of granuloma, the number of macrophages and the collagen fibre content were reduced, yielding improved lung mechanics. "
10/01/1987 - "5. Multiple histological aspects of the acute inflammatory reaction (diapedesis of polymorphs, lymphocytes, histiocytes and macrophages) and features of the chronic inflammatory reaction (newly formed microvascularisation of the granuloma tissue, perivascular oedema, presence of collagen fibres) were improved."
04/01/2011 - "In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). "
06/01/2007 - "In this study, we investigated the role of CBs on granuloma formation induced by lambda-carrageenin-soaked sponge implant in rat. "
10/01/2006 - "Carrageenin induced hind paw oedema and cotton pellet granuloma test in albino rats were employed to study interaction of Vitex negundo (VN) leaf extract with standard antiinflammatory drugs in sub-effective doses per orally to evaluate its potential role as an adjuvant therapy. "
06/01/1996 - "This study suggests that PAF may contribute to the acute phase of an inflammatory state such as the carrageenan-induced granuloma and that it is also present during the chronic process."
09/01/1989 - "Carrageenan granuloma induced subcutaneously in guinea pigs has been widely used in connective tissue studies. "
01/01/2007 - "Granuloma in one was treated successfully with steroids. "
01/01/2004 - "Systemic steroids may be effective in treating recurrent giant pyogenic granulomas during their high-proliferation phase."
01/01/1993 - "Efficacy of steroids on sarcoid granulomas is often dramatic; surgical approach would be discussed in case of ineffective steroid therapy, of persisting questionnable diagnosis, and of tumoral threatening compression."
07/01/1995 - "A seven day cotton pellet granuloma bioassay was employed to study the local and systemic anti-inflammatory activities of these steroids. "
06/01/2015 - "Persistent granulomas either underwent further management with excision or intralesional steroids based on their location. "
|6.||Adrenal Cortex Hormones (Corticosteroids)IBA
03/01/2010 - "Treatment with MDT + corticosteroids does not adversely affect the clearance of granuloma, M. "
06/01/2004 - "This case study suggests that in selected patients with pulmonary hyalinising granuloma experiencing disabling symptoms and worsening pulmonary function, a trial of corticosteroids may be warranted."
12/01/1970 - "[Glass rod granuloma, a method to study the effect of corticosteroids on weights, tensile strength and chemical composition of granuloma tissue in rats]."
02/01/1953 - "Use of granuloma pouch technic in the study of antiphlogistic corticoids."
06/01/2014 - "Two weeks after systemic corticosteroids, the thickness of the granuloma decreased from 568 μm to 356 μm. "
|7.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/01/2008 - "Animal studies show that TNF-alpha inhibition impairs inflammatory cell trafficking and granuloma formation. "
10/01/1993 - "Recent studies have provided evidence that TNF alpha enhances worm fecundity and is essential for granuloma formation. "
09/01/2013 - "Immunohistochemistry showed abundant expression of tumor necrosis factor-α in the granuloma. "
07/07/2013 - "The cytokine tumor necrosis factor-α is known for its important role in granuloma formation. "
03/01/2013 - "Tumor necrosis factor alpha (TNF-a) is a proinflammatory cytokine which plays an important role in the pathogenesis of the disease and the formation of granuloma by regulating cellular proliferation and apoptosis. "
01/01/1994 - "When the attacks were relieved by steroid treatment and/or granuloma resection operation, the total IRI level was decreased and the high-affinity (k1), low-capacity (b1) population of antibodies showed a higher affinity constant and a lower binding capacity than those during the attacks. "
01/01/1996 - "The present study was initiated by unpublished observations that Schaumann bodies-the laminated inclusions often encountered in sarcoid granulomas-cross-reacted with commercial polyclonal antibodies to Mycobacterium bovis, Mycobacterium duvalii and Mycobacterium paratuberculosis. "
01/01/1975 - "These common lesions are probably similar to origin to sperm granulomas, and might be significant in the origin of sperm auto-antibodies; their further study might help to elucidate some of the outstanding problems of male fertility."
08/01/2012 - "Plasma cells detected within the granuloma produced mycobacteria-specific antibodies. "
04/01/2011 - "Six pulmonary samples were immunolabelled with D2-40, anti-CD34 and anti-CD31 antibodies, paying particular attention to the relationships between lymphatics and granulomas, and the pattern of blood microvessels supplying sarcoid lesions. "
|9.||Silicon Dioxide (Sand)FDA LinkGeneric
05/01/2005 - "The characteristic latency period between the time of silica exposure to the time of clinical onset of granuloma, lack of clear-cut histories of exposure in most cases and likelihood of spontaneous resolution, may challenge the diagnosis. "
08/01/1990 - "Spontaneous resolution of silica granuloma."
01/01/1955 - "[Reactions of the reticulo-histiocytic cells to silica; electron microscope study of fibrillogenesis in experimental silicotic granuloma]."
04/01/2015 - "By exploring lung granulomatous responses to silica particles in IL-1-deficient mice, we found that the absence of IL-1α, but not IL-1β, was associated with reduced CD11b(high) phagocytic macrophage accumulation and fewer granulomas. "
06/01/2014 - "A clinical case of cutaneous silica granuloma."
|10.||Praziquantel (Biltricide)FDA Link
11/01/2011 - "The purpose of the present study was to investigate the effect of praziquantel, especially administered persistently, on granuloma formation around Schistosoma japonicum eggs in the lung of sensitized mice. "
12/01/1982 - "Light and electron microscopic studies on Schistosoma mansoni Granulomas of mouse livers following treatment with praziquantel."
04/01/2015 - "Praziquantel (PZQ) has shown some anti-schistosomal effect, but little information is available about the effect of PZQ-prolonged administration on granuloma formation around schistosome eggs. "
11/01/2011 - "However, whether praziquantel has a suppressing effect on granuloma formation around schistosome eggs directly remains unclear. "
11/01/2011 - "Effect of praziquantel prolonged administration on granuloma formation around Schistosoma japonicum eggs in lung of sensitized mice."
07/01/2008 - "The symptoms resolved completely following revision arthroscopy during which the granuloma and the permanent sutures were removed. "
11/01/2015 - "Our study suggests that suture granuloma should be included in the differential diagnosis of a new or recurrent mass detected in patients with a history of prior surgery; however, surgeons must bear in mind that false-positive fluorodeoxyglucose-PET results can be observed in suture granuloma. "
02/01/2005 - "Histopathological study and bacterial culture resulted suture granuloma with Aspergillus. "
03/01/2001 - "The purpose of this study was to examine if suture granulomas display distinct sonographic signs and if these signs enable an accurate preoperative diagnosis. "
12/01/2015 - "Lesions were classified according to the AHA system, and further grouped as calcified or non-calcified (with necrotic cores or suture granulomas). "
|2.||Drug Therapy (Chemotherapy)
01/01/2013 - "TNF inhibition, used as therapy for the treatment of inflammatory diseases, disrupts granuloma allowing replication of mycobacteria which may increase the efficacy of TB chemotherapy. "
12/01/1996 - "Persistence of down regulation of granuloma size was studied in mice chronically infected with Schistosoma mansoni and cured by chemotherapy. "
01/08/2013 - "Drug therapy for solitary cysticercus granuloma: a systematic review and meta-analysis."
02/01/2009 - "In contrast, ulcerative lesions after 8 weeks of chemotherapy showed intra- and extracellular bacterial debris as well as the presence of extensive chronic infiltrates forming huge granulomas. "
01/01/2006 - "The remaining 6 children who were diagnosed to have granulomas at their presentation deteriorated at the follow-up despite regular chemotherapy. "
06/01/1998 - "Six patients with granuloma faciale, including patients with multiple lesions, were treated successfully with cryosurgery. "
01/01/1985 - "Cryosurgery effective for granuloma faciale."
02/01/2006 - "Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale."
01/01/2000 - "[Granuloma faciale: efficacy of cryosurgery in 2 cases]."
06/01/1998 - "[Granuloma eosinophilicum faciei--successful cryosurgery treatment of 6 patients]."
10/01/1998 - "Three hundred and six patients are definitely cured (90%), at the first attempt for 265 patients, after a laser session for granulomas for 20 patients, after a second tracheal resection for 6 patients and after a temporary Montgomery tube for 15 patients. "
01/01/1988 - "The classical treatment is surgical, but laser is helpful in this as in granulomas. "
02/01/2004 - "The aim of this study was to investigate the usefulness of polymerase chain reaction (PCR) detection of Mycobacterium tuberculosis in granulomas isolated by laser capture microdissection (LCM). "
10/01/2002 - "In the studies using a laser doppler perfusion imager, BCEAB (5 nmol site(-1) day(-1)) also attenuated the bFGF-induced increase of local blood flow around the implanted sponge granuloma. "
08/01/2015 - "A laser barrier was placed around the granuloma in the LE. "
01/01/2015 - "Nonetheless, histopathology shows one stent affected by peri-strut granulomas and one stent affected by marked mineralisation. "
01/01/2015 - "The third-generation fully covered self-expandable metallic stent (SEMS) has been developed to solve the problems of difficult removal and in-stent granuloma formation related to the uncovered or partially covered type. "
01/01/2014 - "Evaluation parameters were defined for internal common opening (ICO), ostium stents, and ostium granulomas. "
09/01/2013 - "However, a major adverse effect of stent placement is the formation or reformation of granuloma tissue and the site of the lesion has to be frequently evaluated and treated. "
01/01/2013 - "One granuloma formation and 1 mucus retention triggered the decision to remove the stents. "