|2.||Sexually Transmitted Diseases (Sexually Transmitted Disease)
|3.||Urinary Tract Infections (Urinary Tract Infection)
|1.||Unemo, Magnus: 13 articles (12/2015 - 09/2009)|
|2.||Golden, Matthew R: 10 articles (10/2014 - 03/2004)|
|3.||Hook, Edward W: 9 articles (10/2015 - 10/2002)|
|4.||Centers for Disease Control and Prevention (CDC): 9 articles (08/2012 - 09/2000)|
|5.||Rice, Peter A: 8 articles (12/2015 - 07/2002)|
|6.||Klausner, Jeffrey D: 8 articles (02/2015 - 01/2002)|
|7.||Golparian, Daniel: 8 articles (01/2015 - 07/2011)|
|8.||Hogben, Matthew: 8 articles (08/2010 - 03/2004)|
|9.||Holmes, King K: 8 articles (08/2007 - 04/2003)|
|10.||Weinstock, Hillard S: 7 articles (06/2015 - 03/2004)|
|1.||Ceftriaxone (Ceftriaxon)FDA LinkGeneric
08/01/1995 - "Our data suggest that most prepubertal children with gonorrhea are symptomatic at initial presentation and are cured after recommended treatment with ceftriaxone. "
10/01/2014 - "If oral treatment were 75% effective against decreased susceptibility gonorrhea, exclusive ceftriaxone use would likely increase cure rates in persons with decreased susceptibility gonorrhea, but could diminish them in persons with gonorrhea overall. "
12/01/2012 - "The new superbug Neisseria gonorrhoeae has retained resistance to antimicrobials previously recommended for first-line treatment and has now demonstrated its capacity to develop resistance to the extended-spectrum cephalosporin, ceftriaxone, the last remaining option for first-line empiric treatment of gonorrhea. "
01/01/2015 - "Currently Ceftriaxone is the last remaining antibiotic for first-line treatment of gonorrhea. "
07/01/1989 - "The Centers for Disease Control now recommends ceftriaxone for the first line treatment of gonorrhea but there are no data as to its use in children for this indication. "
|2.||Penicillins (Penicillin)FDA Link
01/01/2005 - "The ethical dilemma of inducing a disease with an unpredictable outcome persisted until the 1940s, when gonorrhea could be reliably cured by penicillin."
12/01/1975 - "[Is there a possibility for gonorrhea patients who cured themselves with peroral penicillin to escape medical evidence]."
08/01/1986 - "Unique strains of Neisseria gonorrhoeae causing epidemic gonorrhea during the penicillin era: a study of isolates from Denmark."
06/01/1983 - "[Results of a clinical laboratory study of the effectiveness of penicillin therapy of gonorrhea in girls]."
06/01/1981 - "[Results of a study of penicillin sensitivity of the gonococcus in women with gonorrhea]."
|3.||Ciprofloxacin (Cipro)FDA LinkGeneric
04/01/2014 - "Recent antimicrobial resistance data for Neisseria gonorrhoeae are lacking in Uganda, where, until 2010, ciprofloxacin was the nationally recommended first-line treatment of presumptive gonorrhea. "
08/01/1986 - "A single 0.25-g dose of ciprofloxacin was effective for treatment of uncomplicated urethral gonorrhea in men, but it did not eradicate coinfection with C. "
08/01/2012 - "The prominence of multidrug resistance suggests that using other classes of antimicrobial drugs for purposes other than treating gonorrhea helped increase the prevalence of ciprofloxacin-resistant strains that are also resistant to those drugs."
07/01/1986 - "Comparative clinical efficacy of two different single-dose ciprofloxacin treatments for uncomplicated gonorrhea."
04/01/2014 - "In this study, we analyzed historical ciprofloxacin resistance data and gonorrhea incidence data to examine the possible effect of antimicrobial drug resistance on gonorrhea incidence at the population level. "
|4.||Azithromycin (Zithromax)FDA LinkGeneric
11/01/1998 - "To examine gonococci not eliminated with 1 g azithromycin therapy to establish treatment outcome/MIC correlates in gonorrhea. "
03/01/1994 - "Azithromycin Gonorrhea Study Group."
02/01/2015 - "These findings support the continued use of azithromycin in a combination therapy regimen for gonorrhea."
01/01/2014 - "First three Neisseria gonorrhoeae isolates with high-level resistance to azithromycin in Sweden: a threat to currently available dual-antimicrobial regimens for treatment of gonorrhea?"
05/01/2013 - "The resistance and intermediate sensitivity of these isolates indicates that caution is recommended in the use of azithromycin and emphasizes the need to establish mechanisms for the surveillance of antimicrobial resistance for the effective control of gonorrhea."
|5.||Cefixime (Suprax)FDA Link
01/01/1997 - "A single 400 mg oral dose of cefixime was effective for the treatment of gonorrhea and was well tolerated by the pregnant women."
09/01/1993 - "Single-dose cefixime 400 mg orally is effective in the treatment of uncomplicated gonorrhea. "
08/01/1993 - "Single-dose oral treatment with cefixime (Suprax) or a quinolone appears to be effective, safe, and practical for patients with uncomplicated gonorrhea. "
01/01/1997 - "Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy."
09/01/1993 - "To assess the efficacy of 200 mg cefixime in the treatment of uncomplicated gonorrhea. "
|6.||Probenecid (Benemid)FDA LinkGeneric
04/01/1989 - "Therefore, the combination of epiciline-probenecid is a valid alternative for routine treatment of acute uncomplicated gonorrhea."
04/01/1989 - "We treated 142 patients with acute uncomplicated gonorrhea with a single oral dose of epiciline-probenecid. "
09/05/1968 - "[Gonorrhea therapy with a combination of probenecid and benzylsodiumpenicillin. "
08/01/1986 - "Cefuroxime axetil alone is effective for urethral gonorrhea in males; rectal gonorrhea probably requires additional probenecid."
02/01/1980 - "The data suggest a possible means by which probenecid improves the efficacy of gonorrhea therapy with aqueous procaine penicillin G. "
|7.||Ofloxacin (Levofloxacin)FDA LinkGeneric
01/01/1990 - "In a study of single-dose ofloxacin treatment of uncomplicated gonorrhea, Neisseria gonorrhoeae was eradicated in all subjects, but C. "
09/01/1993 - "This trend of decreasing susceptibility warrants close monitoring when ofloxacin is used as first-line treatment for gonorrhea."
09/01/1992 - "Although ofloxacin has been used as the first-line treatment for gonorrhea for the last 5 years, there is still no sign of in vitro resistance. "
12/29/1989 - "Single-dose efficacy of ofloxacin in uncomplicated gonorrhea."
06/01/2003 - "On the basis of the presumptive clinical diagnosis of gonorrhea because of the microscopic detection of diplococci in the urethral discharge, he was treated with levofloxacin (300 mg per day) for 7 days. "
|8.||Spectinomycin (Spectinomycin Hydrochloride)FDA Link
01/01/1982 - "Spectinomycin is a broad-spectrum aminocyclitol antibiotic that is highly effective in the treatment of uncomplicated gonorrhea. "
01/01/2013 - "Spectinomycin remains a useful reserve option for therapy of gonorrhea. "
01/01/1993 - "[Effectiveness of trobicin (spectinomycin) effectiveness in acute gonorrhea of men]."
08/01/1992 - "Spectinomycin, which has been in general use against gonorrhea in Thailand since 1983, has dwindling utility, with resistance at a level of 8.9%."
05/01/1988 - "Spectinomycin disk zone diameter as a predictor of outcome in clinical treatment of gonorrhea."
|9.||Nonoxynol (Nonoxynol 9)FDA Link
08/01/2005 - "To understand why clinical trials failed to demonstrate efficacy of nonoxynol-9 in preventing gonorrhea. "
06/01/1994 - "The use of nonoxynol-9 for protection against cervical gonorrhea."
10/01/1998 - "The first "real-life" controlled trial of the spermicide Nonoxynol 9 (N-9) has indicated that N-9 may be ineffective in reducing rates of HIV, gonorrhea, or chlamydia. "
07/01/2001 - "There was a significantly higher incidence of gonorrhea in the nonoxynol-9 group than in the placebo group. "
08/20/1998 - " The rates of gonorrhea were 33.3 and 31.1 cases per 100 woman-years in the nonoxynol-9 and placebo groups, respectively (RR, 1.1; 95% CI, 0.8-1.4), while those of chlamydia were 20.6 and 22.2 cases per 100 woman-years, respectively (RR, 0.9; 95% CI, 0.7-1.3). "
04/30/2004 - "CDC recommends that clinicians no longer use fluoroquinolones as a first-line treatment for gonorrhea in MSM."
05/01/1997 - "To report a case of fluoroquinolone treatment failure in gonorrhea and emergence of a posttreatment isolate with enhanced resistance to fluoroquinolones; and to study mechanisms of quinolone resistance in the isolates from this patient. "
11/01/2015 - "We extracted drug claims associated with gonorrhea diagnosis claims from the MarketScan database for 2000-2010 and calculated the proportion of the drug claims for fluoroquinolones on a monthly basis. "
11/15/2012 - "Fluoroquinolones are no longer recommended for the treatment of gonorrhea because of antimicrobial resistance. "
09/01/2010 - "gonorrhoeae fluoroquinolones are no longer recommended for the treatment of gonorrhea. "
02/01/2004 - "Among 429 participants with known Gc/Ct exposure, consistent condom use was associated with a significant reduction in prevalent gonorrhea and chlamydia (30% vs. 43%; adjusted prevalence odds ratio = 0.42, 95% confidence interval: 0.18, 0.99). "
09/01/2001 - "Special NIH review confirms condoms effective against transmission of HIV, gonorrhea."
11/09/2001 - "Irregular condom use was not protective against HIV or STD and was associated with increased gonorrhea/Chlamydia risk (OR, 1.44; 95% CI, 1.06-1.99). "
03/01/1999 - "This study was undertaken to evaluate the efficacy of condoms and vaginal spermicide products, used alone or in combination, in preventing gonorrhea and chlamydia among women attending an STD clinic. "
11/01/2000 - "Evidence for a positive impact of VCCT services includes facilitated decision-making, acceptance and coping with HIV, improved family and community acceptance, increased condom use, and reduced gonorrhea rates and HIV transmission."
01/01/1994 - "These findings have implications not only for the treatment of gonorrhea but also for other situations where intramuscular injections utilizing a diluent may be necessary."
10/01/1981 - "Twenty-seven episodes of gonorrhea occurring in children less than 15 years of age were treated with an intramuscular injection of cefuroxime, 25 mg/kg. Gonococci were eliminated from genital, pharyngeal, and anal sites in all cases. "
01/26/2004 - "DNA immunization of mice with a plasmid encoding Neisseria gonorrhea PorB protein by intramuscular injection and epidermal particle bombardment."
04/01/1984 - "The high plasma levels were parallelled by high concentrations in SBF, with peaks amounting to 8.4 +/- 1.0 micrograms/ml. Peak concentrations in CBF ranged from 8.1 to 15.7 micrograms/ml. Thus, the pharmacokinetic behavior of ceftizoxime given as a single intramuscular injection of 1 g explained the excellent clinical results of this regimen in uncomplicated gonorrhea."
01/01/1978 - "Systemic toxic were encountered in eight of 10,469 patients during or immediately following the intramuscular injection of 4,800,000 units of procaine penicillin G for the treatment of gonorrhea. "
|3.||Contraception (Birth Control)
07/01/1985 - "The results suggest that not only barrier methods but also other types of contraception were associated with protection against gonorrhea in females. "
07/01/1985 - " Extrapolation of the findings of this study suggests that nearly 200,000 of the 250,000 cases of gonorrhea reported in the US in 1983 could have been averted by use of barrier methods of contraception on the part of noncontraceptors and those using nonbarrier methods."
07/01/1985 - " In some cases, the relationship observed in this study between use of specific contraceptive methods and lower rates of gonorrhea may be biological. "
06/01/2010 - "The role of hormonal contraception on acquisition of gonorrhea has not been well-characterized, as the transmission dynamics of Neisseria gonorrhoeae are poorly understood. "
11/01/1994 - "Reporting experience with gonorrhea was inversely related with receiving contraception education in the last 12 months (OR = 0.6) and living in rural area (OR = 0.5) or in the Midwest (OR = 0.6). "
|4.||Traditional Medicine (Folk Remedies)
04/21/2009 - "This study was conducted to evaluate antigonococcal activity of 22 Thai medicinal plants selected from the plants popularly used in Thai folk medicine for treatment of gonorrhea. "
09/15/2015 - "In Oriental countries, the dried fruits of Schisandra chinensis are extensively used in traditional medicine to treat asthma, gonorrhea, and other diseases. "
03/01/2010 - "In the traditional medicine of Sri Lanka and India, Salacia reticulata bark is considered orally effective in the treatment of rheumatism, gonorrhea, skin disease and diabetes. "
09/01/2014 - "(Combretaceae), a tree that grows in West Africa, has been used in traditional medicine against a variety of diseases such as hepatitis, gonorrhea, skin diseases, and diabetes. "
01/01/2013 - "Saururus chinensis has been used in folk medicine in Korea for the treatment of edema, jaundice, gonorrhea, and several inflammatory diseases. "
|5.||Intrauterine Devices (Intrauterine Device)
03/01/1985 - "Through four vignettes, in which adolescents of different ages and maturity requested confidential care, we assessed the willingness of physicians to give such care for four problems: request for contraceptive, diagnosis of gonorrhea, intrauterine device found incidentally on x-ray study, and illicit drug use. "
08/01/1985 - "[Gonorrhea in women using intrauterine contraceptive devices]."
12/01/2014 - "This article reviews evidence to guide safe and cost-effective testing for asymptomatic Neisseria gonorrhea and Chlamydia trachomatis infection before inserting intrauterine devices (IUDs). "
12/01/2012 - "To evaluate the relationship between Neisseria gonorrhea and Chlamydia trachomatis screening strategies and risk of pelvic inflammatory disease (PID) after intrauterine device (IUD) insertion. "
12/01/2012 - "Neisseria gonorrhea and Chlamydia trachomatis screening at intrauterine device insertion and pelvic inflammatory disease."