|1.||Javitt, Daniel C: 20 articles (04/2013 - 07/2002)|
|2.||Hashimoto, Kenji: 13 articles (01/2015 - 02/2002)|
|3.||Baldwin, Graham S: 12 articles (12/2015 - 12/2004)|
|4.||Shulkes, Arthur: 11 articles (12/2015 - 12/2004)|
|5.||Heresco-Levy, Uriel: 11 articles (04/2013 - 12/2002)|
|6.||Coyle, Joseph T: 10 articles (02/2015 - 04/2002)|
|7.||Chen, Xiaoyuan: 9 articles (08/2014 - 03/2005)|
|8.||Doyle, Jeff J: 8 articles (10/2014 - 07/2002)|
|9.||Nishijima, Saori: 8 articles (09/2008 - 09/2003)|
|10.||Sugaya, Kimio: 8 articles (09/2008 - 09/2003)|
|1.||Schizophrenia (Dementia Praecox)
01/01/1999 - "Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia."
01/01/1997 - "At concentrations relevant to its behavioral actions, GDA significantly inhibits forebrain glycine uptake, indicating that glycine uptake inhibition may provide effective treatment for PCP psychosis and PCP psychosis-like symptoms of schizophrenia."
02/01/2008 - "Since the NMDAR complex consists of multiple sites modulating receptor functions, the efficacy of glycine site potentiators for schizophrenia suggests the possibility that manipulation of other modulating sites of the NMDAR can also be efficacious in the treatment of schizophrenia."
06/01/2014 - "Bitopertin-mediated glycine reuptake inhibition may represent a novel treatment option for schizophrenia, with the potential to address negative symptoms. "
12/01/2010 - "In the meantime, several novel pharmacological strategies, including activation of mGluRs, elevation of synaptic glycine and inhibition of phosphodiesterase 10A, have recently shown promise for the treatment of schizophrenia in clinical trials."
05/15/1995 - "A significant reduction in [3H]glycine binding was found in the hippocampus and thalamus from as early as 1 h after ischemia. "
05/01/2012 - "This study examines the impact of glycine (Gly) preconditioning on ischemia reperfusion (IR)-induced pulmonary mitochondrial injury to research the previously, in pig lungs, demonstrated Gly-dependent amelioration of pulmonary IR injury. "
01/01/2011 - "Experimental studies have shown protective effect by the non-essential amino acid glycine to liver ischemia-reperfusion (I/R) injury but the mechanism of action is unknown. "
01/01/2006 - "The aim of this study was to determine whether glycine decreases IRI after warm hepatic ischemia. "
03/01/2002 - "The purpose of this study was to investigate whether a bolus injection of glycine given before reperfusion plus continuous dietary supplementation afterward would reduce renal injury caused by ischemia-reperfusion. "
10/01/2005 - "Glycine might be beneficial in the protection of myocardial cells against hypoxia. "
12/01/2011 - "Glycine, a nonessential amino acid, is known to possess various protective effects in the kidney, such as a decrease in the deterioration of renal function and a reduction of the damage caused by hypoxia. "
10/01/1997 - "After the transmembrane electrolyte concentration gradient was eliminated by a "intracellular" buffer or by permeabilizing the plasma membrane to molecules <4 kDa using alpha-toxin, anoxia still caused further membrane disruption that was prevented by glycine or low pH. These results demonstrate that 1) water or net electrolyte influxes are probably not a primary cause for anoxia-induced membrane disruption and 2) glycine could prevent the plasma membrane disruption during anoxia independently from its effect on transmembrane electrolyte or water influxes. "
04/01/1997 - "The aim of this study was to investigate the mechanism of cytoprotection by glycine against hypoxia-induced hepatocellular injury. "
01/01/2015 - "Stabilizing hypoxia inducible factor-1α with dimethyloxallyl glycine increased early survival, but not proliferation or differentiation, in neurospheres in vitro and in newly born SGZ cells in vivo. "
08/15/2009 - "To develop new therapeutic agents against renal ischemia/reperfusion injury, we sought to link an antioxidant moiety (nitronyl nitroxide) to glycine in the hope that the resulting glycine-nitronyl nitroxide conjugate (GNN) would provide a synergetic protection against renal ischemia/reperfusion injury. "
11/01/1991 - "Protective effects of glycine during hypothermic renal ischemia-reperfusion injury."
03/15/2003 - "Glycine ameliorates lung reperfusion injury after cold preservation in an ex vivo rat lung model."
03/01/2001 - "These results indicate that some of the indicators of ischemic-reperfusion injury are improved by pretreatment with a 20% glycine solution."
03/01/2001 - "Pretreatment with glycine reduces the severity of warm intestinal ischemic-reperfusion injury in the rat."
02/01/1989 - "After cerebrospinal fluid glycine levels were normalized, the seizures stopped completely in one child and were markedly improved in the other. "
05/01/1983 - "Assuming the recorded pathways were representative of all glycine-mediated spinal pathways, the results suggested that postsynaptic inhibition could be virtually eliminated before intrinsic spinal seizures were triggered. "
05/01/1999 - "Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in addition to possessing activity in the maximal electroshock test, a convulsive model in which glycine is inactive. "
01/01/1998 - "Recently, studies have demonstrated that N-(benzyloxycarbonyl)glycine (1) antagonized seizures superior to glycine in addition to activity in the maximal electroshock (MES) test, a convulsive model where glycine is inactive. "
10/01/2011 - "The increased glycine levels are responsible for worsening of the underlying metabolic condition and increased seizure frequency."
|4.||Glutamic Acid (Glutamate)
|7.||Aspartic Acid (Aspartate)
|1.||Fluid Therapy (Oral Rehydration Therapy)
|3.||Transplantation (Transplant Recipients)
|4.||Protein-Restricted Diet (Diet, Protein Restricted)