|1.||Fukushima, Shoji: 13 articles (11/2011 - 08/2003)|
|2.||Sultana, Sarwat: 12 articles (09/2013 - 08/2004)|
|3.||Saadat, Mostafa: 10 articles (11/2014 - 06/2006)|
|4.||Fryer, A A: 10 articles (02/2005 - 01/2000)|
|5.||Strange, R C: 10 articles (02/2005 - 01/2000)|
|6.||Ali-Osman, Francis: 9 articles (12/2015 - 04/2003)|
|7.||Peters, Wilbert H M: 9 articles (09/2013 - 03/2002)|
|8.||Nelson, William G: 8 articles (01/2014 - 01/2002)|
|9.||Ranson, Hilary: 8 articles (01/2014 - 08/2003)|
|10.||Mitsumori, Kunitoshi: 8 articles (09/2012 - 08/2004)|
01/01/2010 - "Out of the single gene perturbations, activation of glutathione S-transferase P (GSTP1) gene was by far the most effective in blocking the cancer phenotype. "
05/01/2006 - "The 24-mo fermentation was the most effective in preventing cancer by decreasing tumor formation and increasing natural killer cell activity in spleens and glutathione S-transferase activity in livers of mice. "
04/12/1996 - "In search of compounds with improved specificity for targeting the important cancer-associated P1-1 glutathione S-transferase (GST) isozyme, new analogs 4 and 5 of the previously reported glutathione S-transferase (GST)-activated latent alkylating agent gamma-glutamyl-alpha-amino-beta-[[[2-[[bis[bis(2-chloroethyl)amino]ph osp horyl]oxy]ethyl]sulfonyl]propionyl]-(R)-(-)-phenylglycine (3) have been designed, synthesized, and evaluated. "
01/07/2015 - "The 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX, 1), a "suicide inhibitor" of the glutathione-S-transferase GSTP1-1, showed pro-apoptotic properties in tumor cells, but in vivo studies were limited by poor bioavailability and high affinity towards GSTM2-2, expressed in many non-cancerous tissues. "
01/01/2015 - "In this study, we searched for novel binding partners of the influenza A virus NS2 protein, the nuclear export protein responsible for overcoming host range restriction, by a yeast two-hybrid screening assay and glutathione S-transferase-pulldown and coimmunoprecipitation assays and identified AIMP2, a potent tumor suppressor that usually functions to regulate protein stability, as one of the major NS2-binding candidates. "
01/01/1992 - "Sm28, a glutathione-S-transferase, induces significant protection against schistosome infection in rodents and nonhuman primates. "
02/01/2003 - "The efficacy of the Be82 gene product fused with glutathione S-transferase (GST/Be82) in an enzyme-linked immunosorbent assay (ELISA) for the diagnosis of Babesia equi infection was reported previously (H. "
11/01/2015 - "Neither the phi glutathione S-transferase (GST)-encoding gene expression nor the GST (EC 18.104.22.168) activity was modified upon wheat infection by powdery mildew. "
06/01/2015 - "Trichinella spiralis: low vaccine potential of glutathione S-transferase against infections in mice."
02/01/2015 - "Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections."
|3.||Body Weight (Weight, Body)
05/01/1987 - "SKF525-A given intraperitoneally (50 mg/kg body weight) to Sprague-Dawley rats in a single dose promoted a significant reduction in cytosolic glutathione S-transferase (GST) activities 0.5 and 1 h after injection. "
07/01/2008 - "Occurrence of glutathione S-transferase placental form (GST-P)-positive hepatocytes was examined, using 15 Wistar rats of both sexes each orally administered 2,3,7,8-tetrabromo-dibenzo-p-dioxin (TBDD) by gavage at a single dose of 0, 10, 30, 100 or 300 microg/kg body weight. "
11/01/2001 - "Body weight, lung weight and tissue glutathione-S-transferase activity were, however, not altered. "
11/01/1997 - "The volume fraction of the liver occupied by glutathione S-transferase P-positive foci was significantly increased to 2.9, 3.3, and 12% at 300, 1500, and 7500 microg/kg body weight/week, respectively, compared to 1.2% in the controls. "
01/01/1996 - "CHL [50, 100, or 200 mg/kg body weight (b.w.)/day] induced significant increases in the hepatic levels of glutathione S-transferase (GST) and sulfhydryl (-SH) in lactating dams and suckling pups of 14 or 21 days. "
|4.||Colorectal Neoplasms (Colorectal Cancer)
02/01/2012 - "Previous studies investigating the association between the glutathione S-transferase Tl (GSTT1) null genotype and colorectal cancer (CRC) risk in the Asian population have reported controversial results. "
09/01/2014 - "Epigenetic alterations are involved in the overexpression of glutathione S-transferase π-1 in human colorectal cancers."
06/01/2014 - "To investigate the correlation between glutathione S-transferase P1 (GSTP1) Ile105Val polymorphism and colorectal cancer (CRC) risk. "
06/01/2014 - "A systemic review of glutathione S-transferase P1 Ile105Val polymorphism and colorectal cancer risk."
01/01/2014 - "Cruciferous vegetables, glutathione S-transferase polymorphisms, and the risk of colorectal cancer among Chinese men."
05/01/2013 - "The glutathione S-transferase P1 Ile105Val polymorphism markedly modifies allergen-provoked airway inflammation in atopic asthmatics in vivo. "
05/01/2013 - "Yet, little remains known about the regulation of allergic inflammation by glutathione S-transferase P1 in human asthmatics. "
05/01/2013 - "Glutathione S-transferase P1 Ile105Val polymorphism modulates allergen-induced airway inflammation in human atopic asthmatics in vivo."
01/01/2013 - "At sacrifice, the livers of SD rats treated with DEN and HFD exhibited marked development of glutathione S-transferase placental form (GST-P)-positive foci, a hepatic preneoplastic lesion, and this was associated with hepatic steatosis, oxidative stress and inflammation, and hepatocyte proliferation. "
05/01/2012 - "Urine α-Glutathione S-transferase, systemic inflammation and arterial function in juvenile type 1 diabetes."
|1.||Glutathione (Reduced Glutathione)
|4.||Glutathione Reductase (Glutathione-Disulfide Reductase)
|5.||Proteins (Proteins, Gene)
|8.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|10.||O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfate
|1.||Drug Therapy (Chemotherapy)
|2.||Transplantation (Transplant Recipients)
|5.||Homologous Transplantation (Allograft)