|1.||Nephrotic Syndrome (Syndrome, Nephrotic)
|3.||Membranous Glomerulonephritis (Membranous Nephropathy)
|5.||IGA Glomerulonephritis (IGA Nephropathy)
|1.||Kopp, Jeffrey B: 21 articles (04/2015 - 02/2006)|
|2.||Reiser, Jochen: 19 articles (12/2015 - 07/2005)|
|3.||Wei, Changli: 15 articles (12/2015 - 07/2005)|
|4.||Trachtman, Howard: 15 articles (11/2015 - 10/2004)|
|5.||Ghiggeri, Gian Marco: 15 articles (09/2014 - 02/2003)|
|6.||Bagga, Arvind: 11 articles (03/2014 - 04/2003)|
|7.||Wetzels, Jack F M: 10 articles (01/2015 - 07/2002)|
|8.||Hattori, Motoshi: 9 articles (09/2014 - 12/2003)|
|9.||Caridi, Gianluca: 9 articles (05/2014 - 02/2003)|
|10.||Freedman, Barry I: 8 articles (01/2016 - 01/2009)|
|1.||Cyclosporine (Ciclosporin)FDA LinkGeneric
11/01/1999 - "Although cyclosporin is less effective in patients with focal segmental glomerulosclerosis, which is often corticosteroid-resistant, a number of studies indicate that it may be successful both in the few steroid-sensitive patients with frequent relapses and in some corticosteroid-resistant patients. "
04/01/2002 - "Cyclosporin has improved the outcome for steroid-resistant patients with focal glomerulosclerosis, but there is a proportion of patients that are either cyclosporin-resistant or suffer relapses, needing long-term therapy to sustain the remission. "
09/05/1992 - "In only I out of 4 patients with focal segmental glomerulosclerosis was a remission obtained while in two patients with mesangial proliferation the urine remained protein free during cyclosporine treatment. "
12/01/1999 - "A randomized trial of cyclosporine in patients with steroid-resistant focal segmental glomerulosclerosis. "
12/01/1999 - "A randomized trial of cyclosporine in patients with steroid-resistant focal segmental glomerulosclerosis. "
|2.||Idiopathic minimal change nephrotic syndromeIBA
03/01/2002 - "The incidence of focal segmental glomerulosclerosis was significantly greater in biopsies performed in the recent period, group A, 35% versus group B, 16.7%, P=0.05, and in the total number when we included the presumptive minimal change nephrotic syndrome, group A, 15.2% and group B, 5.3%, P<0.0001. "
01/01/2006 - "The above protocol could induce and maintain remission in 81.8% of children with minimal change nephrotic syndrome, 66.7% of children with diffuse mesangial proliferation and in only 16.7% of children with focal segmental glomerulosclerosis at the end of three years of the study. "
10/01/2014 - "Morphological and biochemical studies on renal biopsies from patients with minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS) showed that glomeruli, and in particular podocytes, from MCD patients had higher levels of Beclin1-mediated autophagic activity than glomeruli from FSGS patients. "
09/01/2013 - "In the present study, we aim to measure the serum levels of miR-192 and miR-205 and their correlation with clinicopathological data in patients with primary focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). "
01/01/2013 - "The study was undertaken to develop a potential new markers for distinguishing minimal change nephrotic syndrome (MCNS) and focal segmental glomerulosclerosis (FSGS) in children. "
|3.||Prednisone (Sone)FDA LinkGeneric
06/01/2013 - "Prednisone is a mainstay of treatment for patients with focal segmental glomerulosclerosis (FSGS), a disease characterized by reduced podocyte number and glomerulosclerosis. "
04/01/2013 - "A prospective, multicenter trial was conducted in 9 nephrology centers from 2006 to 2008, in patients with SRNS (defined as failure to respond to 1 mg/kg/day of prednisone for 8, and 16 weeks, in focal segmental glomerulosclerosis). "
09/01/2004 - "Prednisone is the initial treatment of primary focal segmental glomerulosclerosis. "
03/01/2004 - "As the patient had no benefit from the prednisone therapy, she underwent to another biopsy which detected, this time, a Focal Glomerulosclerosis. "
04/15/2003 - "Treatment of recurrent focal glomerulosclerosis after renal transplantation: is prednisone essential to maintain a sustained remission?"
|4.||Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/01/2010 - "We found therapy with cyclophosphamide to be promising in patients with focal segmental glomerulosclerosis."
07/01/2008 - "Group 1 consisted of 22 children [3 focal segmental glomerulosclerosis (FSGS), 19 minimal-change NS (MCNS)] who received cyclophosphamide (CP) orally for 2.5 +/- 0.5 months. "
01/01/2006 - "We herein report the results of intravenous pulse cyclophosphamide (IVCP) therapy of 5 patients with steroid-resistant focal segmental glomerulosclerosis (FSGS). "
01/01/2006 - "Intravenous pulse cyclophosphamide therapy in focal segmental glomerulosclerosis."
09/01/2004 - "Cyclophosphamide in the treatment of focal segmental glomerulosclerosis."
|5.||Tacrolimus (Prograf)FDA LinkGeneric
05/01/2014 - "Efficacy of tacrolimus in the treatment of children with focal segmental glomerulosclerosis."
01/01/2013 - "Toxicity was seen in 7 and 3 patients receiving CyA and tacrolimus, respectively, and 5 patients each with minimal change and focal segmental glomerulosclerosis. "
01/01/2006 - "The use of tacrolimus in steroid-resistant (SR) focal segmental glomerulosclerosis (FSGS) has been reported in single and small series case reports. "
01/01/2006 - "Management of steroid-resistant focal segmental glomerulosclerosis in children using tacrolimus."
03/17/1990 - "FK 506 in steroid-resistant focal sclerosing glomerulonephritis of childhood."
03/01/2001 - "Although much of the interest in pulse methylprednisolone therapy (PMT) has centered around its use in children with focal segmental glomerulosclerosis, PMT has also been shown to be effective in the treatment of other proteinuric renal diseases. "
12/01/2006 - "Methylprednisolone was effective and safe in treating nephrotic children with primary focal segmental glomerulosclerosis. "
06/01/2007 - "Low-dose methylprednisolone pulse therapy in Chinese children with steroid resistant focal segmental glomerulosclerosis."
12/01/2006 - "To examine the effectiveness of pulse methylprednisolone in children with nephrotic primary focal segmental glomerulosclerosis. "
12/01/2006 - "Methylprednisolone treatment in children with nephrotic primary focal segmental glomerulosclerosis."
|7.||Prednisolone (Predate)FDA LinkGeneric
04/01/1994 - "They were divided into groups according to renal pathology: (1) steroid-sensitive NS (SSNS) not receiving prednisolone therapy, (2) SSNS on prednisolone, (3) focal segmental glomerulosclerosis (FSGS), (4) SSNS in remission and not receiving prednisolone therapy, (5) congenital NS (CNS). "
12/01/2007 - "There was initial renal histology of minimal change (MCD) in 28 children, focal segmental glomerulosclerosis (FSGS) in 7 and mesangial proliferative glomerulonephritis (MsPGN) in the other 2. These patients were divided into 2 groups: one group received the induction therapy consisting of intravenous CTX and prednisolone, and the another group were treated with CsA [initial dose 3-5mg/(kg d)] and prednisolone. "
03/01/2011 - "In our study, two important facts were noted: 1) the predominant histopathological subtype was the focal segmental glomerulosclerosis; 2) a high remission rate was achieved in our patients using a combined cyclosporine-prednisolone treatment regimen. "
04/01/2004 - "For steroid resistant focal segmental glomerulosclerosis (FSGS) intravenous pulses of methyl-prednisolone and cyclosporine were also given. "
01/01/1987 - "Cyclosporin and prednisolone: do they prevent recurrence of focal segmental glomerulosclerosis?"
03/01/2001 - "Although focal segmental glomerulosclerosis was initially considered to be a steroid-resistant disease, several studies have shown a better responsiveness to more prolonged courses of steroids. "
07/01/2005 - "Effects of steroids in focal segmental glomerulosclerosis in a predominantly African-American population."
01/01/2008 - "In primary focal segmental glomerulosclerosis, treatment with steroids forecasted a high renal survival and proteinuria remission. "
01/01/2013 - "Half of patients with nephrotic syndrome caused by primary focal segmental glomerulosclerosis (FSGS) have resistance to treatment with steroids. "
09/01/2012 - "It has been proposed as treatment for the idiopathic nephrotic syndrome, recurrent idiopathic nephropathy, and focal segmental glomerulosclerosis refractory to steroids. "
|9.||rituximab (Mabthera)FDA Link
10/01/2013 - "Successful treatment of adult-onset collapsing focal segmental glomerulosclerosis with rituximab."
09/01/2012 - "Treatment with rituximab resulted in amelioration of NS in 17 of the 18 patients with focal segmental glomerulosclerosis (FSGS), while only one patient remained NR. "
01/01/2012 - "Rituximab treatment for adult patients with focal segmental glomerulosclerosis."
12/01/2011 - "Case report: successful treatment of recurrent focal segmental glomerulosclerosis with a novel rituximab regimen."
06/01/2011 - "Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis."
03/01/2012 - "Raised serum creatinine at presentation does not adversely affect steroid response in primary focal segmental glomerulosclerosis in adults."
01/01/2012 - "Association between the proportion of sclerotic glomeruli and serum creatinine in primary focal segmental glomerulosclerosis."
12/01/2006 - "He turned out to be uremic due to focal segmental glomerulosclerosis (creatinine 4.5 mg/dl, MDRD creatinine clearance 12 ml/min). "
01/01/2012 - "Apart from the degree of interstitial fibrosis, the serum level of creatinine and its clearance rate are well correlated with the proportions of both segmentally and globally sclerosed glomeruli in primary focal segmental glomerulosclerosis."
01/01/2008 - "Remarkably, creatinine, focal glomerulosclerosis and interstitial fibrosis were considerably increased under PM/ACEi. "
07/01/2006 - "Plasmapheresis for recurrent posttransplant focal segmental glomerulosclerosis."
03/15/2001 - "Effect of pre-and postoperative plasmapheresis on posttransplant recurrence of focal segmental glomerulosclerosis in children."
12/01/2000 - "The role of plasmapheresis in the treatment of focal segmental glomerulosclerosis (FSGS)."
08/01/1998 - "Plasmapheresis in the treatment of steroid-resistant focal segmental glomerulosclerosis in native kidneys."
11/01/1997 - "Plasmapheresis in the treatment of steroid-resistant focal segmental glomerulosclerosis."
04/01/2005 - "According to data reported by the North American Pediatric Renal Transplantation Cooperative Study, patients with focal segmental glomerulosclerosis (FSGS) as primary renal disease have a recurrence rate of 30% after the first RTx. "
12/27/1997 - "Study of the in vitro effect on glomerular albumin permselectivity of serum before and after renal transplantation in focal segmental glomerulosclerosis."
10/01/2015 - "Recurrence of idiopathic focal segmental glomerulosclerosis (FSGS) after renal transplantation is believed to be caused by a circulating factor(s). "
10/01/2015 - "Recurrent focal segmental glomerulosclerosis after kidney transplantation."
07/01/2015 - "Focal segmental glomerulosclerosis commonly recurs following kidney transplantation. "
|3.||Transplantation (Transplant Recipients)
09/01/1996 - "However, focal segmental glomerulosclerosis manifested sooner after transplantation in study than control patients (mean 37 versus 82 months). "
01/01/2015 - "Data was collected to examine baseline characteristics and outcomes of transplant recipients with HIVAN defined pathologically as collapsing focal segmental glomerulosclerosis (FSGS) with tubulo-interstitial disease. "
12/01/2012 - "The phenomenon of focal segmental glomerulosclerosis post-transplantation--a one-hit wonder?"
07/01/2008 - "Recurrent focal segmental glomerulosclerosis (FSGS) is a major challenge in the field of transplantation. "
06/01/2008 - "Focal segmental glomerulosclerosis (FSGS) is associated with circulating permeability activity (Palb) and recurs after transplantation in about 30% of patients. "
11/01/2013 - "The two subjects with post-transplant recurrence of focal segmental glomerulosclerosis (FSGS) demonstrated the most significant improvement in FSPF (p = 0.006). "
05/01/2013 - "Surveillance biopsies at three and six months post-transplant revealed no evidence for focal segmental glomerulosclerosis in the study group. "
11/01/2000 - "Recurrent focal segmental glomerulosclerosis (FSGS) in renal transplants provides a unique opportunity to study the pathogenesis of FSGS in human beings, because the patients are monitored carefully to identify the onset of disease, the recurrence is presumed to have the same etiology as the primary disease, renal biopsy is a tool to study the pathogenesis of the lesion, and therapeutic intervention provides a mechanism to test pathogenesis. "
06/01/1992 - "Recurrence of focal segmental glomerulosclerosis posttransplantation: a special report of the North American Pediatric Renal Transplant Cooperative Study."
10/01/2015 - "The inclusion criteria were a functioning graft at 1 year posttransplant, data availability and no recurrence of focal-segmental glomerulosclerosis. "
|5.||Homologous Transplantation (Allograft)
06/01/2004 - "Given the differential effect of race on focal segmental glomerulosclerosis (FSGS) progression in native kidneys, recurrence of FSGS in the transplanted kidney, and allograft source, the authors conducted this study to evaluate the influence of FSGS by race and allograft source. "
06/01/2015 - "To explore the role of immunoadsorption (IA) for the treatment of idiopathic focal segmental glomerulosclerosis (FSGS) recurrence in the renal allograft, if applied in a personalized manner. "
03/01/2015 - "Focal segmental glomerulosclerosis in renal allografts: Is it possible to diagnose the etiology?"
09/01/2014 - "Focal segmental glomerulosclerosis recurrence in the renal allograft."
03/01/2013 - "Recurrence of focal segmental glomerulosclerosis (FSGS) in pediatric kidney allografts is associated with poor graft survival. "