Necrotizing Ulcerative Gingivitis (Trench Mouth)

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77 relevant articles (1 outcomes, 6 trials/studies) found for this Disease

Description: An acute or chronic GINGIVITIS characterized by redness and swelling, NECROSIS extending from the interdental papillae along the gingival margins, PAIN; HEMORRHAGE, necrotic odor, and often a pseudomembrane. The condition may extend to the ORAL MUCOSA; TONGUE; PALATE; or PHARYNX. The etiology is somewhat unclear, but may involve a complex of FUSOBACTERIUM NUCLEATUM along with spirochetes BORRELIA or TREPONEMA.

Also Known As:

Trench Mouth; Gingivitis, Necrotizing Ulcerative; Vincent's Infection; Angina, Vincent; Anginas, Vincent; Infection, Vincent; Infection, Vincent's; Mouth, Trench; Stomatitides, Ulcerative; Ulcerative Gingivitis, Necrotizing; Ulcerative Stomatitides; Ulcerative Stomatitis; Vincents Infection; Stomatitis, Ulcerative; Vincent Angina; Vincent Infection

Relationship Network

Disease Context: Research Results

Bacterial Infections and Mycoses

Infection: 225242

Necrotizing Ulcerative Gingivitis: 77

Bacterial Infections: 6830

Gram-Negative Bacterial Infections: 240

Fusobacteriaceae Infections

Fusobacterium Infections: 11

Necrotizing Ulcerative Gingivitis: 77

Stomatognathic Diseases: 273

Mouth Diseases: 56

Periodontal Diseases: 3754

Gingival Diseases: 75

Gingivitis: 1713

Necrotizing Ulcerative Gingivitis: 77

Related Diseases

1.	Dental Plaque
2.	Lichen Planus (Lichen Ruber Planus)
3.	Periodontitis
4.	Gingivitis
5.	Pemphigus (Pemphigus Vulgaris)

Experts

1.	Cacciapuoti, M: 2 articles (03/2004 - 09/2000)
2.	Cozzani, E: 2 articles (03/2004 - 09/2000)
3.	Parodi, A: 2 articles (03/2004 - 09/2000)
4.	Savage, Kofo O: 1 article (09/2005)
5.	Phillips, Reshma S: 1 article (09/2005)
6.	Enwonwu, Cyril O: 1 article (09/2005)
7.	Di Marco, E: 1 article (03/2004)
8.	Zerega, B: 1 article (03/2004)
9.	Descalzi Cancedda, F: 1 article (03/2004)
10.	Schüpbach, P: 1 article (05/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Necrotizing Ulcerative Gingivitis:

1.	Tetracycline (Achromycin)FDA LinkGeneric 12/01/1987 - "intermedius in periodontal lesions and lesions of acute necrotizing ulcerative gingivitis, then tetracycline may be effective in disrupting establishment of these organisms at concentrations well below those required to achieve a bacteriostatic effect." Order ALL the reference details at left...
2.	Immunoglobulin G (IgG)IBA 12/01/1967 - "IgG cryoglobulinaemia Case report and immunological studies of a patient with recurrent ulcerative stomatitis and high content of cold precipitable immunoglobulin in serum." 01/01/2000 - "METHODS: Direct immunofluorescence revealed a speckled pattern of IgG deposits in the basal one-third of the epithelium, while indirect immunofluorescence confirmed the presence of stratified epithelium-specific antinuclear antigen (SES-ANA), both pathognomonic for chronic ulcerative stomatitis. " 09/01/1983 - "Bacterial IgG and IgM antibody titers in acute necrotizing ulcerative gingivitis." 08/01/1991 - "These studies extend recent observations that showed that subjects with acute necrotizing ulcerative gingivitis had both pathogen-related spirochetes in dental plaque and serum immunoglobulin G to pathogen-restricted antigens on T. " 09/01/1983 - "IgG AND IgM ANTIBODY TITERS to eight bacterial isolates were measured by indirect immunofluorescence and ELISA in sera from acute necrotizing ulcerative gingivitis (ANUG) patients during the acute phase, from ANUG patients during the convalescent phase, from patients with gingivitis and from subjects with normal gingiva. " Order ALL the reference details at left...
3.	Fibrinogen (Factor I)IBA 12/01/1987 - "Previous studies from our laboratory have shown that a strain of Bacteroides intermedius, VPI 8944, an organism isolated originally from a patient with acute necrotizing ulcerative gingivitis, binds human fibrinogen rapidly, reversibly, specifically, saturably, and with high affinity (M.S. " 12/01/1986 - "Results of previous studies from our laboratory have shown that a strain of Bacteroides intermedius isolated originally from a patient with acute necrotizing ulcerative gingivitis binds and degrades human fibrinogen (M.S. " Order ALL the reference details at left...
4.	AntigensIBA 03/01/2004 - "The antibody to the 70-kd antigen in chronic ulcerative stomatitis and lichen planus." 01/01/2000 - "METHODS: Direct immunofluorescence revealed a speckled pattern of IgG deposits in the basal one-third of the epithelium, while indirect immunofluorescence confirmed the presence of stratified epithelium-specific antinuclear antigen (SES-ANA), both pathognomonic for chronic ulcerative stomatitis. " 08/01/1991 - "These studies extend recent observations that showed that subjects with acute necrotizing ulcerative gingivitis had both pathogen-related spirochetes in dental plaque and serum immunoglobulin G to pathogen-restricted antigens on T. " 09/01/2008 - "METHODS: We studied the pre-immune and immune serum of a rabbit immunized with a peptide corresponding to the N-terminus of the 70-kDa antigen chronic ulcerative stomatitis protein; sera from two patients, one with oral erosive lichen planus and one with cutaneous lichen planus who presented stratified epithelium-specific antinuclear antibodies at high titer; and a third serum from a patient with cutaneous lichen planus without stratified epithelium-specific antinuclear antibodies. " 09/01/2008 - "Patients with oral erosive and cutaneous lichen planus may have antibodies directed against the chronic ulcerative stomatitis protein antigen of 70-kDa." Order ALL the reference details at left...
5.	Immunoglobulins (Immunoglobulin)IBA 12/01/1967 - "IgG cryoglobulinaemia Case report and immunological studies of a patient with recurrent ulcerative stomatitis and high content of cold precipitable immunoglobulin in serum." Order ALL the reference details at left...
6.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 06/01/1965 - "STUDIES OF VITAMIN-C IN ULCERATIVE STOMATITIS." Order ALL the reference details at left...
7.	cupric sulfide (CuS)IBA 07/01/2008 - "Chronic ulcerative stomatitis (CUS) is a recently described condition with specific immunopathologic findings. " 09/01/2007 - "Chronic ulcerative stomatitis (CUS) is a recently described mucocutaneous condition in which patients experience chronic, painful, ulcerative lesions of the oral mucosa. " 08/01/2007 - "Chronic ulcerative stomatitis (CUS) is a recently described mucocutaneous disease characterized by involvement of mucosal surfaces and skin. " 12/01/2003 - "Chronic ulcerative stomatitis (CUS) is a mucocutaneous disease primarily involving mucosal surfaces, but occasionally may involve the skin. " 10/01/2001 - "CUSP, the most abundant cutaneous product of p63, has been identified as an autoantigen in chronic ulcerative stomatitis (CUS). " Order ALL the reference details at left...
8.	Antinuclear AntibodiesIBA 04/01/1996 - "Another case is reported herein and the subject of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies (SES-ANA) is reviewed. " 04/01/1996 - "Chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies." 05/01/1992 - "Chronic ulcerative stomatitis associated with stratified epithelial specific antinuclear antibodies. " 05/01/1991 - "Ten cases of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibody." 02/01/1990 - "Both in vivo binding to the oral mucosa and skin of a stratified epithelium-specific antinuclear antibody and high titers of these antibodies in serum are markers of this disease, which we refer to as chronic ulcerative stomatitis associated with stratified epithelium-specific antinuclear antibody." Order ALL the reference details at left...
9.	Penicillins (Penicillin)FDA Link 07/01/1984 - "However, they are useful for cases of acute necrotizing ulcerative gingivitis requiring systemic antibiotic therapy when penicillin is precluded. " 01/01/1951 - "[Treatment of ulcerative stomatitis with penicillin candy]" 01/01/1950 - "[Treatment of acute forms of ulcerative stomatitis with penicillin.]" 11/01/1948 - "Penicillin in the treatment of Vincent's infection; a survey." 12/01/1947 - "[Treatment of Plaut-Vincent angina by intramuscular injections of penicillin.]" Order ALL the reference details at left...
10.	AntibodiesIBA 09/01/2000 - "Chronic ulcerative stomatitis: antibodies reacting with the 70-kDa molecule react with epithelial nuclei." 09/01/2008 - "CONCLUSIONS: Our results confirm that antibodies specifically directed against the chronic ulcerative stomatitis protein are not a distinctive marker of chronic ulcerative stomatitis, but may also be detected in oral erosive and cutaneous lichen planus." 06/01/2007 - "BACKGROUND: Antibodies to stratified epithelia characterize chronic ulcerative stomatitis, an entity that very closely resembles erosive lichen planus both clinically and histologically. " 02/01/1990 - "Both in vivo binding to the oral mucosa and skin of a stratified epithelium-specific antinuclear antibody and high titers of these antibodies in serum are markers of this disease, which we refer to as chronic ulcerative stomatitis associated with stratified epithelium-specific antinuclear antibody." 09/01/2008 - "Patients with oral erosive and cutaneous lichen planus may have antibodies directed against the chronic ulcerative stomatitis protein antigen of 70-kDa." Order ALL the reference details at left...

Therapies and Procedures

1.	Oral Hygiene (Dental Hygiene) 11/01/1993 - "This study was designed to determine the association between oral hygiene status and necrotizing ulcerative gingivitis (NUG), as well as the severity of NUG in Nigerian children. " 11/01/1993 - "Oral hygiene status and necrotizing ulcerative gingivitis in Nigerian children." 03/01/2006 - "Summary INTRODUCTION: Poor oral hygiene, measles and malnutrition have been implicated as predisposing factors to Acute Necrotizing Ulcerative Gingivitis (ANUG) and cancrum oris, common oral diseases prevalent among children ages 3-6 years in rural communities. " Order ALL the reference details at left...
2.	Periodontics 03/01/1987 - "ABC's periodontics: "V" is for Vincent's infection." 11/01/1979 - "Periodontics--special emphasis emergencies: necrotizing ulcerative gingivitis and third molars." Order ALL the reference details at left...
3.	Dental Scaling 02/01/1991 - "The purpose of this paper is to review the treatment modalities of acute necrotizing ulcerative gingivitis and illustrate an alternative treatment approach of periodic scaling, root planing, and antimicrobial rinses with 0.12% chlorhexidine. " Order ALL the reference details at left...
4.	Traditional Medicine (Folk Remedies) 04/04/2007 - "(Family: Oleaceae) is used in folk medicine for treating ulcerative stomatitis, skin diseases, ulcers, wounds, corns - a hard or soft hyperkeratosis of the sole of the human foot secondary to friction and pressure (Stedman's Medical Dictionary, 28th ed. " Order ALL the reference details at left...
5.	Intramuscular Injections 12/01/1947 - "[Treatment of Plaut-Vincent angina by intramuscular injections of penicillin.]" Order ALL the reference details at left...

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