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G(M3) Ganglioside

A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Also Known As:
Ganglioside GM3; II3NeuAcLacCer; Sialyl Lactosylceramide; GM3, Ganglioside; Lactosylceramide, Sialyl; Hematoside; Sialyllactosylceramide
Networked: 168 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rengifo, Enrique: 7 articles (01/2015 - 10/2004)
2. Carr, Adriana: 7 articles (01/2015 - 01/2011)
3. Rengifo, Charles E: 7 articles (01/2015 - 01/2011)
4. Kabayama, Kazuya: 7 articles (01/2012 - 02/2002)
5. Blanco, Rancés: 6 articles (01/2015 - 01/2011)
6. Cedeño, Mercedes: 6 articles (01/2015 - 01/2011)
7. Lee, Young-Choon: 6 articles (08/2014 - 07/2006)
8. Chung, Tae-Wook: 6 articles (08/2014 - 07/2006)
9. Kim, Cheorl-Ho: 6 articles (08/2014 - 07/2006)
10. Choi, Hee-Jung: 6 articles (08/2014 - 07/2006)

Related Diseases

1. Experimental Melanoma
2. Mucolipidoses (Sialidosis)
3. Lewis Lung Carcinoma
4. Neoplasms (Cancer)
5. Melanoma (Melanoma, Malignant)

Related Drugs and Biologics

1. N-Acetylneuraminic Acid (Sialic Acid)
2. CDw17 antigen (lactosylceramide)
3. ceramide trihexoside
4. RV 538 (PDMP)
5. Insulin Receptor
6. Epidermal Growth Factor (EGF)
7. HK1-ceramide 2
8. Antigens
9. Gangliosides
10. Neuraminidase (Sialidase)

Related Therapies and Procedures

1. Immunotherapy