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Fumarate Hydratase (Fumarase)

An enzyme that catalyzes the reversible hydration of fumaric acid to yield L-malic acid. It is one of the citric acid cycle enzymes. EC 4.2.1.2.
Also Known As:
Fumarase; Hydratase, Fumarate; (S)-Malate hydro-lyase
Networked: 192 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Linehan, W Marston: 19 articles (12/2014 - 12/2003)
2. Aaltonen, Lauri A: 14 articles (11/2013 - 04/2002)
3. Launonen, Virpi: 12 articles (11/2010 - 04/2002)
4. Pollard, Patrick J: 11 articles (05/2014 - 01/2006)
5. Kiuru, Maija: 10 articles (06/2010 - 04/2002)
6. Lehtonen, Rainer: 8 articles (06/2010 - 04/2002)
7. Yang, Youfeng: 7 articles (12/2014 - 08/2009)
8. Aittomäki, Kristiina: 7 articles (06/2010 - 04/2002)
9. Frizzell, Norma: 6 articles (11/2015 - 10/2011)
10. Neckers, Len: 6 articles (12/2014 - 08/2005)

Related Diseases

1. Cataract (Cataracts)
2. Neoplasms (Cancer)
3. Kidney Neoplasms (Kidney Cancer)
4. Renal Cell Carcinoma (Grawitz Tumor)
5. Leiomyoma (Uterine Fibroids)

Related Drugs and Biologics

1. Ibuprofen (Motrin)
2. Catalase
3. Succinate Dehydrogenase (Fumarate Reductase)
4. hereditary Leiomyomatosis and renal cell cancer
5. Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))
6. Oxidoreductases
7. Aconitate Hydratase (Aconitase)
8. Reed's syndrome
9. L-Lactate Dehydrogenase (Lactate Dehydrogenase)
10. Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)

Related Therapies and Procedures

1. Ligation