A poxvirus infection of poultry and other birds characterized by the formation of wart-like nodules on the skin and diphtheritic necrotic masses (cankers) in the upper digestive and respiratory tracts.
Also Known As:
Bird Pox; Fowl Pox; Diphtheria, Fowl; Diphtherias, Fowl; Fowl Diphtherias; Pox, Bird; Pox, Fowl; Birdpox; Epithelioma Contagiosum; Fowl Diphtheria; Variola Avium
Networked: 166 relevant articles (12 outcomes, 28 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Influenza in Birds (Avian Flu)
2. Vaccinia
3. Melanoma (Melanoma, Malignant)
4. Human Influenza (Influenza)
5. Ovarian Neoplasms (Ovarian Cancer)


1. Schlom, Jeffrey: 13 articles (10/2010 - 10/2002)
2. Radaelli, Antonia: 9 articles (01/2015 - 01/2003)
3. Zanotto, Carlo: 8 articles (01/2015 - 01/2003)
4. Hodge, James W: 8 articles (10/2010 - 10/2002)
5. Gulley, James L: 7 articles (09/2015 - 02/2005)
6. Arlen, Philip M: 7 articles (09/2015 - 02/2005)
7. De Giuli Morghen, Carlo: 7 articles (01/2015 - 01/2003)
8. Hill, Adrian V S: 7 articles (12/2009 - 06/2004)
9. Panicali, Dennis: 7 articles (12/2008 - 07/2003)
10. Swayne, David E: 6 articles (01/2014 - 03/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fowlpox:
1. VaccinesIBA
2. Hemagglutinins (Hemagglutinin)IBA
3. AntigensIBA
4. DNA (Deoxyribonucleic Acid)IBA
5. AntibodiesIBA
6. DisinfectantsIBA
7. Bacterial VaccinesIBA
8. Prostate-Specific Antigen (Semenogelase)IBA
01/01/2015 - "PROSTVAC immunotherapy is a heterologous prime-boost regimen of two different recombinant pox-virus vectors; vaccinia as the primary immunotherapy, followed by boosters employing fowlpox, to provoke immune responses against prostate-specific antigen. "
09/01/2015 - "E9802 was a phase 2 multi-institution study conducted to evaluate the safety and effectiveness of vaccinia and fowlpox prostate-specific antigen (PSA) vaccine (step 1) followed by combination with androgen ablation therapy (step 2) in patients with PSA progression without visible metastasis. "
10/01/2007 - "Patients were given recombinant fowlpox-prostate specific antigen/triad of co-stimulatory molecules alone or recombinant vaccinia-prostate specific antigen/triad of co-stimulatory molecules followed by recombinant fowlpox-prostate specific antigen/triad of co-stimulatory molecules on a prime and boost schedule with or without recombinant-granulocyte-macrophage colony-stimulating factor protein or recombinant fowlpox-granulocyte-macrophage colony-stimulating factor vector. "
02/01/2002 - "The serum IgG response to cell surface antigens expressed on LNCAP [prostate-specific antigen (PSA)-positive] and PC-3 (PSA-negative) were analyzed in individuals with advanced disease receiving vaccinia- or fowlpox-expressed PSA (v-PSA or f-PSA, respectively) by flow cytometry. "
01/01/2006 - "Based on previous studies that demonstrated the safety profile and preliminary clinical activity of prostate specific antigen (PSA) targeted therapeutic vaccines, as well as recent laboratory data supporting the value of the addition of co-stimulatory molecules B7-1, ICAM-1, and LFA-3 (designated TRICOM) to these vaccines, we conducted a Phase I study to evaluate the safety and immunogenicity of a novel vaccinia and fowlpox vaccine incorporating the PSA gene sequence and TRICOM. "
9. Proteins (Proteins, Gene)IBA
10. Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
07/01/2004 - "We show here that freshly isolated human B cells can be efficiently infected by a replication-defective fowlpox recombinant vector, designated rF-TRICOM (TRIad of COstimulatory Molecules), to markedly increase surface expression of the human costimulatory molecule B7-1 and moderately increase expression of intercellular adhesion molecule-1 (ICAM-1) and leukocyte function-associated antigen-3 (LFA-3). "
05/15/2008 - "We report here a pilot study of 25 patients treated with a poxviral vaccine regimen consisting of the genes for CEA and MUC-1, along with a triad of costimulatory molecules (TRICOM; composed of B7.1, intercellular adhesion molecule 1, and lymphocyte function-associated antigen 3) engineered into vaccinia (PANVAC-V) as a prime vaccination and into fowlpox (PANVAC-F) as a booster vaccination. "
05/01/2003 - "These mice were vaccinated with recombinant poxviral vectors [recombinant vaccinia, recombinant fowlpox (rF)] encoding the CEA transgene as well as a triad of costimulatory molecules [B7-1, ICAM-1, and LFA-3 (TRICOM)]. "
08/02/2000 - "Two recombinant poxvirus vectors (replication-defective avipox [fowlpox; rF] and a replication-competent vaccinia [rV]) have been engineered to express a triad of costimulatory molecules (B7-1, intercellular adhesion molecule-1, and leukocyte function-associated antigen-3; designated TRICOM). "
10/15/2002 - "The vaccines used were recombinant vaccinia virus containing the transgenes for CEA and three T-cell costimulatory molecules [B7-1, ICAM-1, and LFA-3, designated recombinant vaccinia (rV)-CEA/TRICOM], with each transgene under the control of individual poxvirus promoters, and a replication-defective avipox virus (fowlpox; rF) containing the same four transgenes (designated rF-CEA/TRICOM). "

Therapies and Procedures

1. Tissue Therapy (Cell Therapy)
2. Highly Active Antiretroviral Therapy (HAART)
3. Intradermal Injections
4. Immunotherapy