Foreign-Body Reaction

04/26/2020 - "Recently, various studies using different autologous stem cells have achieved promising results by improving the pelvic ligament and muscle regeneration and conferring the tissue elasticity and strength to the damaged tissue in PFD, as well as reduced inflammatory reactions, collagen deposition, and foreign body reaction. "
12/01/2012 - "A morphological study was also carried out to evaluate the foreign body reaction and the formation of neovascularization and collagen. "
04/01/2010 - "Subsequent studies are needed to elucidate interaction of collagen and MMP-2 in chronic foreign body reaction."
01/01/2002 - "To study the spatiotemporal processes of angiogenesis during a foreign body reaction (FBR), biodegradable bovine collagen type-1 (COL-I) discs were implanted in mice for a period up to 28 days. "
04/01/1984 - "Histologic study of the collagen implant fails to show evidence of significant foreign body reaction. "

06/01/2017 - "Regarding biocompatibility, the in vivo evaluation performed by histological analysis, showed a mild to moderate chronic inflammatory reaction with no foreign body reaction, demonstrating that both hydrogels show good results for in vivo biodegradation and biocompatibility, therefore are most adequate for biomedical applications."
03/15/2011 - "The objectives for this study were to characterize the temporal evolution of the foreign body reaction (FBR) to acellular PEG-based hydrogels prepared from PEG diacrylate precursors when implanted subcutaneously in immunocompentent c57bl/6 mice by (immuno)histochemical analysis and gene expression. "
06/01/2001 - "Pathologic studies of these expanded fragments of hydrogel material after removal showed in vivo hydrolysis with foreign body reaction and dystrophic calcification. "
09/01/1998 - "Subcutaneous implantation studies in mice showed that in vivo the hydrogel was biocompatible since the foreign body reaction seen around the implanted hydrogel samples was moderate and became minimal upon increasing implantation time. "
01/01/2023 - "Precision porous templated scaffolds (PTS) are a hydrogel construct of uniformly sized interconnected spherical pores that induce a pro-healing response (reducing the foreign body reaction, FBR) exclusively when the pores are 30-40µm in diameter. "

01/01/2020 - "However, even polypropylene (PP), endorsed as the "gold standard" of all prosthetic materials used in this field, is still subject to many complications caused by the foreign body reaction (FBR). "
01/01/2022 - "Characterization of innate and adaptive immune cells involved in the foreign body reaction to polypropylene meshes in the human abdomen."
01/01/2021 - "In conclusion, in our animal model, microporous and heavy-weight polypropylene meshes produce greater inflammatory and foreign body reaction. "
04/01/2013 - "Cross-linked biological and TIGR MSM meshes demonstrated highest tensile strength but were only partially incorporated, with similar foreign body reaction and adhesion formation as polypropylene meshes in the TIGR MSM group, and minimal degradation and moderate adhesion formation in the cross-linked biological group. "
09/01/2010 - "However, infectious complications associated with erosions have occasionally been reported because of a foreign body reaction to the polypropylene mesh. "

12/01/2003 - "When extensive mass loss started, a mild-to-moderate secondary foreign body reaction, related to clearance of the polymer fragments, was triggered. "
09/01/2001 - "This study further confirmed the biocompatibility of the polymer, with no foreign body reaction in any of the groups. "
08/15/2018 - "In group E animals, a minimal foreign body reaction was observed around the polymer. "
04/01/2017 - "Interfacing Polymers and Tissues: Quantitative Local Assessment of the Foreign Body Reaction of Mononuclear Phagocytes to Polymeric Materials."
12/01/2014 - "Foreign body reaction to hydrophilic polymer was recently reported. "

10/01/1997 - "No signs of degradation of or of an osteolytic foreign-body reaction to poly(L-lactide) at the host tissue-implant interface could be observed within the follow-up times of this study."
05/01/1990 - "It is concluded that the biodegradable poly (L-lactic acid) used in these implantation studies is tissue compatible, and evokes a foreign body reaction with minor macrophage and giant cell activity, as observed during this 3-week implantation period. "
10/01/2020 - "Foreign Body Reaction to Poly-D-L-Lactic Acid Resorbable Plates Used in Craniofacial Surgery."
06/13/2018 - "Furthermore, the dried PU films assembled from PU NPs have a similar effect on macrophage polarization and present a smaller shifting foreign body reaction (FBR) in vivo than the conventional poly(l-lactic acid). "
12/01/2014 - "To the authors' knowledge, this report is the first description of a patient presenting with a delayed foreign body reaction to a broken poly-L-lactic acid bioabsorbable screw at the lateral femoral epicondyle after posterolateral corner reconstruction. "

08/01/1996 - "While it is evident that poly-p-dioxanon is less reactive than polyglycolide, recent studies, including the case above, have shown that Orthosorb pins are not exempt from the same type of foreign-body reaction as the Biofix products."
11/01/1994 - "The authors present two case studies which describe a destructive, nonspecific foreign-body reaction encountered while using the Biofix absorbable rod system. "
08/01/1992 - "The degradation of polyglycolide was accompanied histologically by a typical non-specific foreign-body reaction. "
01/01/2003 - "All three suture materials produced a foreign body reaction; the least severe was with polyglycolic acid sutures. "
05/01/1996 - "Foreign-body reaction and the course of osteolysis after polyglycolide implants for fracture fixation: experimental study in sheep."

08/01/1989 - "Based on the results of the present study and on previous biomechanical data, expanded PTFE should be considered as a material for pulley reconstruction; it is incorporated by host tissues, elicits no foreign body reaction and causes no adhesions or traumatic changes to underlying flexor tendons. "
04/28/2018 - "On the contrary, the implantation of a synthetic matrix made of polytetrafluoroethylene used as control was only surrounded by vWF⁺ cells, with no cell migration inside the scaffold and clear foreign body reaction (giant cells were visible). "
06/01/2008 - "Teflon implant wear debris particles appear to trigger a multinucleated giant cell foreign body reaction. "
04/01/2008 - "eComment: Foreign body reaction to polytetrafluoroethylene."
01/01/2000 - "Histopathology findings showed that PTFE patches created a strong peripheral foreign body reaction with dystrophic calcification, whereas FP was well incorporated with intrapatch fibroblastic activity and neovascularsation. "

12/26/2013 - "The lifetime and efficacy of a subcutaneously implanted glucose biosensor could be greatly improved by a self-cleaning membrane capable of periodic physical removal of adhered cells associated with the foreign body reaction. "
12/23/2022 - "Despite the success of continuous glucose measuring systems operating through the skin for about 14 days, long-term implantable biosensors are facing challenges caused by the foreign-body reaction. "
06/25/2019 - "A self-cleaning, mechanically robust membrane for minimizing the foreign body reaction: towards extending the lifetime of sub-Q glucose biosensors."
12/30/2015 - "The foreign body reaction is the major cause of the dysfunction and relatively short lifetime associated with implanted glucose biosensors. "
02/15/2011 - "Collectively, the results suggest that intermittent sustained NO release from implant surfaces may improve glucose diffusion for subcutaneously implanted sensors by mitigating the foreign body reaction."

06/01/1986 - "The absorption of Vicryl mesh results in a temporary but pronounced foreign-body reaction. "
06/01/1986 - "According to studies by Dociu (1978), the resorption of Vicryl sutures causes only a slight foreign-body reaction in the back musculature of rats. "
01/01/2008 - "Early biological response of fibroblasts as a major component of foreign body reaction was most affected by the filament construction of the mesh combining polypropylene with multifilament, partially absorbable polyglactin fibres. "
07/01/1989 - "Furthermore, development of absorbable suture material like Dexon and Vicryl benefited by minimizing granulation stenosis at anastomosis due to less foreign body reaction. "
04/01/2000 - "In the late phase Vicryl was surrounded by an increasing amount of multinucleated macrophages and a thin capsule, whilst around Resolut and Bio-Gide a strong foreign body reaction was observed. "

01/01/2021 - "Curcumin treatment significantly reduced inflammation, foreign body reaction, granulation tissue formation, medulla spinalis retraction, and EF formation compared with positive control group (P < 0.05); however, no significant differences were found between the 2 groups that received different doses of curcumin. "
01/01/2021 - "The results of the present study showed that systemic administration of curcumin was effective in reducing EF formation, inflammation, granulation tissue formation, medulla spinalis retraction, and foreign body reaction in the laminectomy area. "

03/01/1982 - "The new suture material is distinguished by greatly extended absorption time, low foreign body reaction and an improved tensile strength. "
10/08/2022 - "Eight consecutive patients who were confirmed as having an intra-tendinous suture foreign body reaction in the histopathological report were enrolled in this study. "
01/01/2017 - "The findings from our in vitro study suggest that four commonly used suture materials cause upregulation of pro-inflammatory markers indicative of an early foreign body reaction, with no balance from anti-inflammatory markers. "
05/01/2023 - "LTS may decrease the inflammatory and foreign body reaction caused by sutures. "
10/08/2022 - "In conclusion, intra-tendinous suture reaction is a rare complication following an Achilles tendon repair using nonabsorbable suture material, but it can be treated adequately with only surgical excision of foreign body reaction tissue and primary repair using absorbable suture material."

12/01/2020 - "This case report represents the late-onset foreign body reaction due to PLLA facial injections."
08/01/2016 - "To our knowledge, a general consensus of staging and treatment guidelines for managing gluteal foreign body reaction to injectables has not yet been established. "
08/01/2016 - "A staging system for gluteal foreign body reaction to injectables."
02/01/2009 - "Injectable implants used for soft-tissue augmentation may lead to a granulomatous foreign-body reaction. "
07/01/2020 - "Injections from illegal fillers resulted to foreign body reaction (22 cases, 78.6%) and infections (6 cases, 21.4%). "

04/01/1998 - "OBJECTIVE: This study evaluates the effect of stent deployment pressure on stent deployment, coronary vessel injury, subacute reclosure and foreign body reaction in a porcine coronary model. "
02/01/2023 - "Foreign body reaction after CyPass® Micro-Stent implantation: a case series."
12/01/2015 - "Only a few inflammatory cells were seen in the PCL/PLGA stent group after 12 weeks, and the foreign body reaction was more severe in the control group. "
08/01/2006 - "In addition to the well-known foreign body reaction around the graft, numerous polymorphonuclear cells characteristic of the first step of healing were present in tissues around stent-grafts retrieved at surgical conversion. "
07/01/2001 - "Hydrolyzation of the stent was histologically evident at 12 months, with mild foreign-body reaction detectable in 2 of 5 aortas sampled at this time point. "

01/01/2014 - "Using a novel technique for PET/US fusion, ultrasound and PET were coregistered to clarify that PET hypermetabolism was due to a foreign body reaction after plug hernioplasty performed several years earlier. "
05/01/2016 - "Surgical mesh, commonly used in hernioplasty, has been associated with increased F-FDG uptake related to an inflammatory foreign body reaction and is a known cause of false-positive PET scans. "
01/01/2023 - "The aim of this study was twofold: to describe the pathophysiology of autoimmunity and foreign body reaction and to undertake a systematic review of surgical mesh implanted at the time of hernia repair and the subsequent development of autoimmune disease. "
10/01/2015 - "Moreover, the three stitch hernioplasty method is a simple method, easy for the beginners to adopt, has less foreign body reaction, less time consuming, causes less tissue trauma, and lesser chance for vascular injury."
01/01/2016 - "At 2 and 12 weeks, oxidative damage, fibroblast accumulation, apoptosis and macrophages were significantly decreased in coated PPM samples compared to uncoated PPM. These results demonstrate that a non-biodegradable hydrogel coating of PPM led to significant reduction in foreign body reaction, oxidative stress and apoptosis compared to uncoated PPM in vivo, and suggest that this coating could be clinically useful in hernia repair."

01/01/2020 - "Future studies should focus on the development of absorbable implants with improved biocompatibility aiming to further decrease the potential of foreign-body reaction and eliminate the need for additional reoperative procedures."
03/01/2014 - "Local foreign-body reaction to commercial biodegradable implants: an in vivo animal study."
12/01/2010 - "Delayed foreign-body reaction to absorbable implants in metacarpal fracture treatment."
01/01/2019 - "Absorbable Implant Foreign Body Reaction Masquerading as Orbital Cellulitis."
03/01/2007 - "However, bioabsorbable implants elicit a local foreign-body reaction that may lead to osteolysis. "