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Foot-and-Mouth Disease

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Also Known As:

Foot and Mouth Disease; Disease, Foot-and-Mouth; Diseases, Foot-and-Mouth; Foot-and-Mouth Diseases

Networked: 514 relevant articles (16 outcomes, 42 trials/studies) for this Disease, Comments

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Disease Context: Research Results

Virus Diseases: 1327
- RNA Virus Infections: 50
  - Picornaviridae Infections: 39
    - Foot-and-Mouth Disease: 514
Animal Diseases: 117
- Foot-and-Mouth Disease: 514

Related Diseases

1.	Classical Swine Fever (Swine Fever)
2.	Pseudorabies
3.	Human Influenza (Influenza)
4.	Tuberculosis
5.	Malaria

Experts

1.	Barnett, P V: 10 articles (04/2008 - 02/2001)
2.	Paton, D J: 7 articles (04/2008 - 05/2005)
3.	Neitzert, E: 6 articles (07/2008 - 01/2000)
4.	Malirat, V: 6 articles (07/2008 - 01/2000)
5.	Bergmann, I E: 6 articles (07/2008 - 01/2000)
6.	De Clercq, K: 6 articles (06/2008 - 12/2001)
7.	Dekker, A: 5 articles (03/2009 - 11/2003)
8.	Goris, N: 5 articles (06/2008 - 11/2006)
9.	Reid, S M: 5 articles (03/2008 - 12/2001)
10.	Ferris, N P: 5 articles (03/2008 - 09/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Foot-and-Mouth Disease:

1.	VaccinesIBA 03/01/1985 - "Improved foot and mouth disease (FMD) vaccines which have increased efficiency and stability are highly desirable. " 03/01/2009 - "Although present conventional foot-and-mouth disease (FMD) vaccines can prevent clinical disease, protection is short lived ( approximately 6 months), often requiring frequent revaccination for prophylactic control, and vaccination does not induce rapid protection against challenge or prevent the development of the carrier state. " 04/07/2008 - "Previous work in pigs, has demonstrated that full protection against foot-and-mouth disease (FMD) can be achieved following vaccination with chimeric foot-and-mouth disease virus (FMDV) vaccines, in which the VP1 G-H loop had been substituted with that from another serotype. " 12/01/2002 - "Prospects, including time-frames, for improved foot and mouth disease vaccines." 09/01/1996 - "Natural and vaccine-induced immunity to foot and mouth disease: the prospects for improved vaccines." Order ALL the reference details at left...
2.	SaponinsIBA 01/01/1976 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. " 06/01/1973 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. " 06/01/1967 - "[On several tests of the value of saponin used alone as an adjuvant in the preparation of foot-and-mouth disease vaccine]" 03/01/1965 - "[On the active immunization of swine against foot-and-mouth disease using saponin vaccine]" 05/01/1972 - "[Efficacy of foot-and-mouth disease vaccine in pigs treated with formaldehyde GOA saponin prepared with A22 foot-and-mouth virus]" Order ALL the reference details at left...
3.	DNA (Deoxyribonucleic Acid)IBA 01/01/2005 - "DNA vaccine has been tested for protection against foot-and-mouth disease. " 09/01/2006 - "DNA vaccination against foot-and-mouth disease via electroporation: study of molecular approaches for enhancing VP1 antigenicity." 08/01/2008 - "Enhanced immune response of DNA vaccine (VP1-pCDNA) adsorbed on cationic PLG for foot and mouth disease in guinea pigs." 08/01/2007 - "Effects of chronic heat stress on immune responses of the foot-and-mouth disease DNA vaccination." 01/15/2006 - "Extract from Agaricus blazei Murill can enhance immune responses elicited by DNA vaccine against foot-and-mouth disease." Order ALL the reference details at left...
4.	hydroxide ionIBA 01/01/1977 - "A foot-and-mouth disease trivalent vaccine composed of strains A24 Cruzeiro, O1 Caseros and C2 Resende elicited no immune response in swine when adjuvanted with aluminium hydroxide but was effective when emulsified in oil. " 12/13/2008 - "Ten male Arabian oryx (Oryx leucoryx) were vaccinated with a commercially available standard aqueous foot-and-mouth-disease vaccine containing aluminium hydroxide as an adjuvant, and their antibody titres against serotypes O and A were measured using solid-phase blocking elisa and the virus neutralisation test. " 07/01/1970 - "Immunological studies with cell cultured aluminium hydroxide gel adsorbed formalin inactivated foot and mouth disease type Asia I monovalent vaccine." 10/01/2007 - "Outbreaks of foot-and-mouth disease (FMD) from January 1982 through December 2003 were used to examine variations in serotype- and species-specific risk for three control programmes in Colombia: (1982-1983) vaccination, using an aluminium hydroxide, saponin adjuvant, required but not enforced; (1984-1996) vaccination, using an oil double-emulsion adjuvant, required but not enforced; and (1997-2003) enforced vaccination, using an oil double-emulsion adjuvant, restricted animal movement enforced, and slaughter of infected animals. " 06/21/2002 - "Immune responses of goats against foot-and-mouth disease quadrivalent vaccine: comparison of double oil emulsion and aluminium hydroxide gel vaccines in eliciting immunity." Order ALL the reference details at left...
5.	Neutralizing AntibodiesIBA 02/01/1989 - "The resulting novel type of vaccine tripalmitoyl-S-glyceryl-cysteinylserylseryl-FMDV-VP1 (135-154) induces a long-lasting high protection against foot-and-mouth disease and serotype-specific virus-neutralizing antibodies in guinea-pigs after a single administration without any additional adjuvant or carrier. " 11/01/1962 - "Studies on the nature of the nature of the neutralization reaction and the competition for neutralizing antibody between components of the virus system of foot-and-mouth disease." 01/01/1992 - "A potency test method for foot and mouth disease vaccine based on the serum neutralizing antibody response produced in cattle." 01/01/1990 - "[Seasonal variations in the formation of virus-neutralizing antibodies in cattle after vaccination against foot-and-mouth disease]" 04/01/1987 - "Sources of variability in foot and mouth disease vaccine potency estimates based on serum neutralizing antibody assay." Order ALL the reference details at left...
6.	Formaldehyde (Formol)IBA 09/01/1969 - "[Control of the activity of anti-foot-and-mouth disease GOA-formol vaccine on mice]" 09/01/1966 - "[On the immunizing properties of GOAL-formol vaccine and GNKI dry virus vaccine against foot-and-mouth disease]" 05/01/1972 - "[Efficacy of foot-and-mouth disease vaccine in pigs treated with formaldehyde GOA saponin prepared with A22 foot-and-mouth virus]" 07/01/1970 - "Immunological studies with cell cultured aluminium hydroxide gel adsorbed formalin inactivated foot and mouth disease type Asia I monovalent vaccine." 01/01/1999 - "The first experimental vaccines against foot-and-mouth disease were made in 1925 by Vallee, Carre and Rinjard using formaldehyde inactivation of tongue tissue from cattle infected with the virus. " Order ALL the reference details at left...
7.	Capsid Proteins (Capsid Protein)IBA 03/01/1999 - "Evidence of partial protection against foot-and-mouth disease in cattle immunized with a recombinant adenovirus vector expressing the precursor polypeptide (P1) of foot-and-mouth disease virus capsid proteins." 12/01/2005 - "Non-capsid proteins to identify foot-and-mouth disease viral circulation in cattle irrespective of vaccination." 07/01/2002 - "A reverse transcription-dependent polymerase chain reaction (RT-PCR) is described that amplifies the genes encoding the capsid proteins VP1-3 of at least three evolutionary lineages each of the foot-and-mouth disease (FMD) virus types A, Asia1 and O. " 01/01/1993 - "Protection of swine against foot-and-mouth disease with viral capsid proteins expressed in heterologous systems." 12/01/1989 - "These results show that in the course of a foot-and-mouth disease outbreak, immunologically relevant amino acid substitutions occur mainly in viral capsid protein VP1." Order ALL the reference details at left...
8.	Immunoglobulin FragmentsIBA 03/18/2009 - "We aim to develop a method that confers rapid protection against foot-and-mouth disease (FMD) by passive immunization with recombinant llama single-domain antibody fragments (VHHs). " 03/18/2009 - "Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs." 03/10/2007 - "Passive immunization of guinea pigs with llama single-domain antibody fragments against foot-and-mouth disease." 11/25/2008 - "Passive immunization of pigs with bispecific llama single-domain antibody fragments against foot-and-mouth disease and porcine immunoglobulin." Order ALL the reference details at left...
9.	Complement System Proteins (Complement)IBA 05/01/1976 - "[Study of immunity in foot-and-mouth disease using the complement-binding inhibition reaction]" 10/01/1973 - "[Quantitative studies of the complement fixation technique after Wadsworth, Maltaner and Maltaner in the foot-and-mouth disease. " 10/01/1973 - "[Quantitative studies of the complement fixation technique after Wadsworth, Maltaner and Maltaner in foot-and-mouth disease. " 07/01/1973 - "[Quantitative studies of the complement fixation technique after Wadsworth, Maltaner & Maltaner in the foot-and-mouth disease. " 05/01/1988 - "A comparison of enzyme-linked immunosorbent assay, complement fixation and virus isolation for foot and mouth disease diagnosis." Order ALL the reference details at left...
10.	AntigensIBA 05/01/1986 - "Foot-and-mouth disease vaccination: a multifactorial study of the influence of antigen dose and potentially competitive immunogens on the response of cattle of different ages." 04/01/1966 - "[Preparation of concentrated foot-and-mouth disease antigen on cell culture for the study of 3 "O" type variants: O Flanders--O Sicily 58--O Spain 64]" 04/01/2007 - "Antigen and vaccine banks: technical requirements and the role of the european antigen bank in emergency foot and mouth disease vaccination." 03/01/2007 - "Initial results demonstrating the feasibility of a multiplexed liquid array immunoassay for foot-and-mouth disease viral antigen detection and simultaneous serotype differentiation are presented. " 04/12/2006 - "Previous work, in sheep vaccinated with emergency foot-and-mouth disease (FMD) vaccine, indicated the benefit of increasing the antigen payload in inhibiting local virus replication and consequently persistence following an indirect aerosol challenge with a virus homologous to the vaccine strain. " Order ALL the reference details at left...

Therapies and Procedures

1.	Corneal Transplantation (Keratoplasty) 01/01/2009 - "Pig is used both for the prevention of foot-and-mouth disease and human diseases, sheep is a model for corneal transplantation, and the horse naturally develops arthritis. " Order ALL the reference details at left...
2.	Skin Transplantation (Skin Grafting) 05/01/2004 - "A sloughed hoof in a young bull as a sequela of foot and mouth disease was treated by skin grafting. " Order ALL the reference details at left...
3.	Organotherapy 01/01/1953 - "[Foot-and-mouth disease; isotherapy, organotherapy and homeotherapy.]" Order ALL the reference details at left...
4.	Microspheres (Microsphere) 07/01/2000 - "Latex beads agglutination (LA) for the detection of the antibody against virus infection-associated (VIA) antigen of foot-and-mouth disease (FMD) virus was estimated using experimentally infected animals. " 07/01/2000 - "Application of latex beads agglutination test for the detection of the antibody against virus-infection-associated (VIA) antigen of foot-and-mouth disease (FMD) virus." Order ALL the reference details at left...
5.	Intravenous Injections 11/05/1962 - "[The prevention of foot-and-mouth disease in cattle by intravenous injection of purified lactoglobulin antibodies.]" Order ALL the reference details at left...

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