Folic Acid (Vitamin M)

A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Also Known As:
Vitamin M; Folacin; Folate; Folic Acid, (D)-Isomer; Folic Acid, (DL)-Isomer; Folic Acid, Calcium Salt (1:1); Folic Acid, Monopotassium Salt; Folic Acid, Monosodium Salt; Folic Acid, Potassium Salt; Folic Acid, Sodium Salt; Folvite; Pteroylglutamic Acid; L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
Networked: 11697 relevant articles (563 outcomes, 1936 trials/studies)

Relationship Network

Drug Context: Research Results


1. Low, Philip S: 70 articles (10/2015 - 05/2002)
2. Selhub, Jacob: 58 articles (12/2015 - 02/2002)
3. Scott, John M: 44 articles (06/2015 - 01/2002)
4. Leamon, Christopher P: 43 articles (07/2015 - 06/2002)
5. Finnell, Richard H: 41 articles (04/2015 - 02/2002)
6. Willett, Walter C: 38 articles (12/2015 - 03/2002)
7. Vollset, Stein Emil: 35 articles (12/2015 - 01/2003)
8. Müller, Cristina: 35 articles (10/2015 - 05/2006)
9. Lee, Robert J: 34 articles (11/2015 - 01/2002)
10. Ulrich, Cornelia M: 34 articles (10/2015 - 05/2002)

Related Diseases

1. Neoplasms (Cancer)
06/01/2003 - "Folate is one of the important constituents of vegetables and fruits that may provide protection against cancer. "
09/13/2002 - "Nevertheless, prominent examples do exist where folate targeting has significantly improved the outcome of a macromolecule-based therapy, leading to complete cures of established tumors in many cases. "
08/01/2002 - "Understanding the mechanisms by which folate status modulates carcinogenesis is important for advancing insight into cancer biology and for facilitating those efforts to translate research in folate and carcinogenesis into effective and safe public health initiatives."
07/07/2012 - "The proposed imaging technique combines several well-established individual concepts into one novel integrated procedure and significantly improves its tumor-imaging capability: the near-infrared excitation for UCNs minimizes tissue autofluorescence and allows imaging into deeper tissue; the improvement in the signal to noise ratio (SNR) is at least a magnitude better than that of a conventional fluorescence imaging technique, and the modification of UCNs with folic acid significantly improves the tumor targeting efficiency by utilizing its affinity for the folic acid receptor that is often over expressed in tumors. "
12/01/2011 - "We suggest that the synergistic effect of folate receptor-mediated internalization and VRP-mediated overcoming MDR could be beneficial in treatment of MDR solid tumors by targeting delivery of micellar PTX into tumor cells. "
2. Neural Tube Defects (Exencephaly)
3. Hyperhomocysteinemia
4. Stroke (Strokes)
5. Anemia

Related Drugs and Biologics

1. Folic Acid (Vitamin M)
2. Vitamin B 12 (Cyanocobalamin)
3. Homocysteine
4. Vitamins
5. Methotrexate (Mexate)
6. Iron
7. Vitamin B 6
8. Micronutrients
9. Liposomes (Liposome)
10. Pyridoxine (Pyridoxin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Renal Dialysis (Hemodialysis)
4. Transplantation (Transplant Recipients)
5. Transplants (Transplant)