Flucytosine (Ancobon)

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695 relevant articles (91 outcomes, 59 trials/studies) found for this Drug

Description: A fluorinated cytosine analog that is used as an antifungal agent.

Also Known As:

Ancobon; Alcobon; Allphar Brand of Flucytosine; Ancotil; CSP Brand of Flucytosine; Dermatech Brand of Flucytosine; ICN Pharmaceuticals Brand of Flucytosine; Roche Brand of Flucytosine; 5-Fluorocytosine; 2(1H)-Pyrimidinone, 4-amino-5-fluoro-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

N(4)-hydroxy-5-fluorocytosine

Experts

1.	Hamada, H: 3 articles (07/2000 - 01/2000)
2.	Dromer, Françoise: 2 articles (01/2008 - 01/2006)
3.	Lortholary, Olivier: 2 articles (01/2008 - 01/2006)
4.	Reed, Paul: 2 articles (10/2007 - 08/2005)
5.	Sharp, Andrew: 2 articles (10/2007 - 08/2005)
6.	Keevil, Brian: 2 articles (10/2007 - 08/2005)
7.	Hope, William W: 2 articles (10/2007 - 08/2005)
8.	Drusano, George L: 2 articles (10/2007 - 08/2005)
9.	Warn, Peter A: 2 articles (10/2007 - 08/2005)
10.	Denning, David W: 2 articles (10/2007 - 08/2005)

Related Diseases

1.	Infection 06/01/1975 - "The fungi infection was successfully eradicated by a single oral dose of 5-Fluorocytosine (20 mg/kg) after each dialysis treatment" 01/01/1995 - "Flucytosine is effective in the treatment of serious fungal infections" 08/01/1984 - "The combination of bursectomy and flucytosine treatment cured the infection." 08/01/1978 - "The infection responded well to treatment with 5-fluorocytosine" 11/01/1975 - "No resistance to 5-fluorocytosine developed, and the candida infection was eradicated" Get all the results and reference details, order at left...
2.	Cryptococcosis 01/01/1976 - "Multiple lymphonodular cryptococcosis, cured by 5-fluorocytosine." 04/01/2003 - "Flucytosine and cryptococcosis: which in vitro test is the best predictor of outcome?" 08/01/1998 - "Flucytosine (5-FC) monotherapy for cryptococcosis is not advocated because drug resistance emerges during therapy" 08/01/1998 - "Flucytosine monotherapy for cryptococcosis." 01/19/1980 - "Treatment of cryptococcosis with flucytosine]" Get all the results and reference details, order at left...
3.	Candidiasis (Moniliasis) 12/01/1996 - "Efficacy of continuous flucytosine infusion against Candida lusitaniae in experimental hematogenous murine candidiasis." 09/01/1988 - "Clinical efficacy of flucytosine on urinary candidiasis]" 01/01/1985 - "In a previous study with flucytosine (5-FC) susceptibility of 40 Candida albicans isolates in vitro proved statistically correlated with response in systemic murine candidiasis in vivo, although exceptions occurred with individual isolates" 11/01/2006 - "We used a pharmacodynamic model of disseminated candidiasis to define an in vivo drug exposure breakpoint for flucytosine (5FC) against Candida albicans" 11/01/2005 - "For acute disseminated candidiasis, the combination of DAMB plus flucytosine is recommended" Get all the results and reference details, order at left...
4.	Acquired Immunodeficiency Syndrome (AIDS) 10/01/1999 - "Disseminated acanthamoeba infection in a patient with AIDS: response to 5-fluorocytosine therapy." 12/09/1988 - "Anaphylaxis to flucytosine in a patient with AIDS." 06/01/1998 - "These data indicate that treatment with fluconazole and short-term flucytosine is a cost-effective and safe regimen that improves the quality of life for patients with AIDS-associated CM in developing countries where human immunodeficiency virus is endemic." 04/01/1988 - "Mycological-diagnostic assessment of the efficacy of amphotericin B + flucytosine to control Cryptococcus neoformans in AIDS patients." 02/01/1995 - "Thirty-one consecutive AIDS patients with cryptococcal disease were enrolled in a study of the efficacy and safety of short-course primary treatment with a relatively high dose of amphotericin B (1 mg/[kg.d] for 14 days); 26 patients also received flucytosine (100-150 mg/[kg.d], given either intravenously or orally)" Get all the results and reference details, order at left...
5.	Cryptococcal Meningitis 10/01/2007 - "CONCLUSION: The present study demonstrated the substantial increasing of survival time of HIV-infected patients with cryptococcal meningitis by initiated ART even in a resource limited setting (no flucytosine, local combined antiretroviral drugs with NVP based regimens)." 07/01/2008 - "METHODS: Sixty-four HIV-seropositive, antiretroviral therapy-naive patients in Cape Town, South Africa, who experienced their first episode of cryptococcal meningitis during the period May 2005-June 2006 were randomized to receive either (1) AmB, 0.7 mg/kg per day, plus flucytosine, 25 mg/kg 4 times per day (group 1; 30 patients); or (2) AmB, 1 mg/kg per day, plus flucytosine, 25 mg/kg 4 times per day (group 2; 34 patients)" 03/01/2007 - "Oral versus intravenous flucytosine in patients with human immunodeficiency virus-associated cryptococcal meningitis." 10/01/2000 - "For instance, AmB plus flucytosine is preferred in cryptococcal meningitis and candidemia" 09/01/1987 - "19F nuclear magnetic resonance was used for the analysis of flucytosine (FC; 5-fluorocytosine) metabolites in biological fluids of a patient with cryptococcal meningitis who was intravenously injected with this drug at a daily dose of 7.5 g (2.5 g at 8-hr intervals)" Get all the results and reference details, order at left...
158 Diseases and 695 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Amphotericin B (Amphotericin)
2.	Fluconazole (Zonal)
3.	Itraconazole (Sporanox)
4.	Cytosine Deaminase
5.	Ketoconazole (Nizoral)
6.	Antifungal Agents
7.	AmBisome (liposomal amphotericin B)
8.	Fluorouracil (Carac)
9.	Ganciclovir (Cytovene)
10.	Thymidine Kinase
115 Drugs and Important Bio-Agents and 522 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Transplantation (Transplant Recipients)
2.	Drug Therapy (Chemotherapy)
3.	Aftercare (After-Treatment)
4.	Decompression
5.	Atherectomy
27 Therapies and Procedures and 78 more articles analyzed in the Research Interface, order at left...

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