Flail Chest

Subscribe to Selected New Research on Flail Chest

99 relevant articles (6 outcomes, 4 trials/studies) found for this Disease

Description: A complication of multiple rib fractures, rib and sternum fractures, or thoracic surgery. A portion of the chest wall becomes isolated from the thoracic cage and exhibits paradoxical respiration.

Also Known As:

Chest, Flail; Chest, Stove-in; Stove in Chest; Stove-in Chest

Relationship Network

Disease Context: Research Results

Disorders of Environmental Origin

Wounds and Injuries: 60713

Thoracic Injuries: 309

Flail Chest: 99

Related Diseases

1.	Syndrome
2.	Pain (Aches)
3.	Dislocations
4.	Brain Injuries (Brain Injury)
5.	Wounds and Injuries (Trauma)

Experts

1.	Linton, David M: 1 article (12/2006)
2.	Sviri, Sigal: 1 article (12/2006)
3.	Sato, Sshisan: 1 article (08/2006)
4.	Nagahiro, Itaru: 1 article (08/2006)
5.	Yaida, Yutaka: 1 article (08/2006)
6.	Ishii, Noriko: 1 article (08/2006)
7.	Doi, Yoshitesu: 1 article (08/2006)
8.	Kurasako, Toshiaki: 1 article (08/2006)
9.	Matsumoto, Mutsuko: 1 article (08/2006)
10.	Al-Ansari, Mariam A: 1 article (08/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Flail Chest:

1.	Polypropylenes (Polypropylene)IBA 01/01/2002 - "Reconstruction using Marlex mesh combined with moldable metal plates was carried out to prevent flail chest in nine patients, resection alone was performed in five patients, and a muscular flap was used in two patients" 05/01/1997 - "An unusual case of flail chest: surgical repair using Marlex mesh." 01/01/2006 - "A second repair with Marlex and stainless-steel mesh was required in two patients; for flail chest after an autologous bone graft in one; and following re-recurrence of breast carcinoma in another patient who had undergone a musculocutaneous flap repair" Order ALL the reference details at left...
2.	OxygenIBA 02/01/2007 - "Isolated flail chest may be successfully managed with aggressive pulmonary toilet including facemask oxygen, CPAP, and chest physiotherapy" 10/01/1979 - "Effects of contusion and flail chest on pulmonary perfusion and oxygen exchange." 06/01/1996 - "The effect on ventilatory function of fixation of a flail segment in internal (FIP) and external (FEP) position and oxygen administration was studied in an experimental flail chest with pleural indemnity" Order ALL the reference details at left...
3.	Methylprednisolone FDA LinkGeneric 01/01/1985 - "Accordingly, we have since 1976 administered high doses of methylprednisolone already on admission in patients with multiple rib fractures and/or flail chest (30 mg/kg i.v. X 3 at 8 hr intervals)" 09/01/1987 - "Thus, on admission methylprednisolone 30 mg/kg body weight was given to 107 patients having at least four rib fractures or a flail chest" 03/01/1992 - "Seven patients with varying degrees of paradoxical chest wall movement (flail chest) were managed conservatively at the University of Port Harcourt Teaching Hospital with frusemide, methylprednisolone, non administration of crystalloid fluids and limitation of fluid intake" Order ALL the reference details at left...
4.	Methylmethacrylate (Metaplex)IBA 06/01/2006 - "We describe a simple and practical method of operative stabilization of flail chest using a prosthetic mesh and methylmethacrylate anchored to the ribs and sternum" 06/01/2006 - "Operative stabilization of flail chest using a prosthetic mesh and methylmethacrylate." Order ALL the reference details at left...
5.	Stainless Steel (Steel, Stainless)IBA 01/01/2006 - "A second repair with Marlex and stainless-steel mesh was required in two patients; for flail chest after an autologous bone graft in one; and following re-recurrence of breast carcinoma in another patient who had undergone a musculocutaneous flap repair" Order ALL the reference details at left...
6.	Polytetrafluoroethylene (Teflon)FDA Link 06/01/1996 - "The effect on ventilatory function of fixation of a flail segment in internal (FIP) and external (FEP) position and oxygen administration was studied in an experimental flail chest with pleural indemnity" Order ALL the reference details at left...
7.	PolyestersIBA 04/01/1992 - "In conclusion, the polyester mesh prevents flail chest and seems to be a satisfactory material for chest wall reconstruction." Order ALL the reference details at left...
8.	Meperidine (Pethidine)FDA LinkGeneric 11/01/1985 - "A 76-year-old man with a flail chest injury was given a lumber epidural injection of meperidine" Order ALL the reference details at left...
9.	HormonesIBA 05/01/1980 - "The authors measured antidiuretic hormone (ADH) excretion and renal and cardiovascular function in eight patients with flail chest during four ventilatory conditions: continuous positive-pressure ventilation (CPPV), intermittent positive pressure ventilation (IPPV), spontaneous breathing with continuous positive airway pressure (CPAP) and spontaneous breathing (SB)" Order ALL the reference details at left...
10.	Furosemide (Lasix)FDA LinkGeneric 03/01/1992 - "Seven patients with varying degrees of paradoxical chest wall movement (flail chest) were managed conservatively at the University of Port Harcourt Teaching Hospital with frusemide, methylprednisolone, non administration of crystalloid fluids and limitation of fluid intake" Order ALL the reference details at left...

Therapies and Procedures

1.	Artificial Respiration (Mechanical Ventilation) 01/01/1984 - "Patients with traumatic flail chest and paradoxical respiration need first of all immediate intubation and artificial respiration, afterwards operative stabilization is beneficial in selected patients" 10/01/1990 - "We conclude that 40% of flail chest are controllable without mechanical ventilation and that the result of this conservative therapy is superior to any other treatments." 04/01/2002 - "METHODS: Thirty-seven consecutive severe flail chest patients who required mechanical ventilation were enrolled in this study" 03/01/1980 - "Spirometric study of flail chest treated by artificial respiration]" 12/01/2005 - "Through a prospective randomized comparative study, treatment of flail chest by a non-surgical method of packing, strapping, and mechanical ventilation vs. surgical fixation were compared" Order ALL the reference details at left...
2.	Intermittent Positive-Pressure Ventilation 12/01/1995 - "Among 64 cases of flail chest injury, 25 were managed by internal fixation of ribs, whereas the remaining 38 were managed by endotracheal intubation and intermittent positive-pressure ventilation alone" 05/01/2005 - "A comparative study of continuous positive airway pressure (CPAP) and intermittent positive pressure ventilation (IPPV) in patients with flail chest." 03/01/2002 - "However, IPPV has not proven to be beneficial in traumatic brain injury and flail chest, in the absence of other indications." 05/01/2005 - "We conducted a prospective, randomised study of continuous positive airway pressure (CPAP) given via a face mask to spontaneously breathing patients compared with intermittent positive pressure ventilation (IPPV) with endotracheal intubation (ETI) in 52 patients with flail chest who required mechanical ventilation" 05/01/1980 - "The authors measured antidiuretic hormone (ADH) excretion and renal and cardiovascular function in eight patients with flail chest during four ventilatory conditions: continuous positive-pressure ventilation (CPPV), intermittent positive pressure ventilation (IPPV), spontaneous breathing with continuous positive airway pressure (CPAP) and spontaneous breathing (SB)" Order ALL the reference details at left...
3.	Intensive Care (Surgical Intensive Care) 01/01/1993 - "In the ten survivors with flail chest, stability was achieved without secondary dislocation, giving good pain relief, improved respiratory mechanics and reduced duration of ventilatory support and intensive care requirements" 05/01/1977 - "A patient with flail-chest injury, and associated abdominal and musculo-skeletal trauma, required several modes of mechanical ventilation in the Surgical Intensive Care Unit Ventilator modalities included mechanical ventilation with positive end-expiratory pressure (PEEP) and intermittent mandatory ventilation (IMV) with continuous positive airway pressure (CPAP) during 12 days of intensive respiratory care" Order ALL the reference details at left...
4.	Drug Therapy (Chemotherapy) 03/01/1980 - "On the other hand, prolonged stabilization of the chest wall in the second patient until a chemotherapy-induced remission occurred was associated with resolution of the flail chest." Order ALL the reference details at left...
5.	Continuous Positive Airway Pressure 01/01/2001 - "During the second half of the period examined, we routinely adopted three characteristic procedures in the treatment of flail chest injury, namely, pressure support on spontaneous breathing, continuous positive airway pressure via a mask, and respiratory physical therapy by physical therapists" 05/01/2005 - "A comparative study of continuous positive airway pressure (CPAP) and intermittent positive pressure ventilation (IPPV) in patients with flail chest." 05/01/2005 - "We conducted a prospective, randomised study of continuous positive airway pressure (CPAP) given via a face mask to spontaneously breathing patients compared with intermittent positive pressure ventilation (IPPV) with endotracheal intubation (ETI) in 52 patients with flail chest who required mechanical ventilation" 05/01/1977 - "A patient with flail-chest injury, and associated abdominal and musculo-skeletal trauma, required several modes of mechanical ventilation in the Surgical Intensive Care Unit Ventilator modalities included mechanical ventilation with positive end-expiratory pressure (PEEP) and intermittent mandatory ventilation (IMV) with continuous positive airway pressure (CPAP) during 12 days of intensive respiratory care" 05/01/1980 - "The authors measured antidiuretic hormone (ADH) excretion and renal and cardiovascular function in eight patients with flail chest during four ventilatory conditions: continuous positive-pressure ventilation (CPPV), intermittent positive pressure ventilation (IPPV), spontaneous breathing with continuous positive airway pressure (CPAP) and spontaneous breathing (SB)" Order ALL the reference details at left...

Best Treatments:
Research Summary Report
on Flail Chest

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 6 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>