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Fibrous Dysplasia of Bone

A disease of bone marked by thinning of the cortex and replacement of bone marrow by gritty fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC). (From Dorland, 28th ed)
Also Known As:
Bone Fibrous Dysplasia; Bone Fibrous Dysplasias; Osteitis Fibrosa Disseminata
Networked: 53 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Polyostotic Fibrous Dysplasia (McCune Albright Syndrome)
3. Neoplasms (Cancer)
4. Precocious Puberty
5. Osteoporosis

Experts

1. Collins, Michael T: 4 articles (11/2014 - 08/2006)
2. Lala, R: 4 articles (08/2002 - 02/2000)
3. Matarazzo, P: 4 articles (08/2002 - 02/2000)
4. Robey, Pamela G: 3 articles (11/2014 - 08/2006)
5. Bastepe, Murat: 3 articles (11/2011 - 09/2007)
6. de Sanctis, C: 3 articles (08/2002 - 02/2000)
7. Chapurlat, Roland: 2 articles (12/2014 - 09/2008)
8. Bianco, Paolo: 2 articles (11/2014 - 11/2014)
9. Riminucci, Mara: 2 articles (11/2014 - 11/2014)
10. Kelly, Marilyn H: 2 articles (11/2014 - 08/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fibrous Dysplasia of Bone:
1. pegvisomantFDA LinkGeneric
2. Alendronate (Alendronate Sodium)FDA LinkGeneric
3. pamidronate (APD)FDA LinkGeneric
4. GTP Phosphohydrolases (GTPases)IBA
5. DiphosphonatesIBA
6. Codon (Codons)IBA
7. Gs GTP-Binding Protein alpha Subunits (G(s)alpha)IBA
8. GTP-Binding Proteins (G-Protein)IBA
9. Testosterone (Sustanon)FDA Link
10. Growth Hormone (Somatotropin)IBA

Therapies and Procedures

1. Transplants (Transplant)
2. Bone Transplantation (Bone Grafting)
3. Curettage
4. Ovariectomy (Oophorectomy)
5. Osteotomy