Fibrocystic Breast Disease (Chronic Cystic Mastitis)

234  relevant articles (8 outcomes, 39 trials/studies) found for this Disease

Chronic Cystic Mastitis; Mammary Dysplasia; Adenosis of Breast; Cystic Breast Disease; Cystic Disease of Breast; Fibrocystic Changes of Breast; Fibrocystic Disease of Breast; Microglandular Adenosis; Adenoses, Microglandular; Adenosis, Microglandular; Breast Adenosis; Breast Cystic Disease; Breast Cystic Diseases; Breast Disease, Cystic; Breast Disease, Fibrocystic; Breast Fibrocystic Change; Breast Fibrocystic Changes; Breast Fibrocystic Disease; Cystic Mastitis, Chronic; Disease, Cystic Breast; Disease, Fibrocystic Breast; Dysplasia, Breast; Dysplasia, Mammary; Mastopathy, Fibrocystic; Microglandular Adenoses; Breast Dysplasia; Fibrocystic Mastopathy

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Fibroadenoma
2.	Endometrial Neoplasms (Endometrial Cancer)
3.	Leiomyoma (Uterine Fibroids)
4.	Iron-Deficiency Anemia (Anemia, Iron Deficiency)
5.	Hemorrhage

Experts

1.	Castillo, Eugenio: 1 article (11/2006)
2.	Mirabent, Felio: 1 article (11/2006)
3.	Garibay, Miguel: 1 article (11/2006)
4.	Rezaei, Michaeal: 1 article (04/2006)
5.	Mousavi, Seyed R: 1 article (04/2006)
6.	Reszeć, Joanna: 1 article (11/2003)
7.	Sulkowska, Mariola: 1 article (11/2003)
8.	Famulski, Waldemar: 1 article (11/2003)
9.	Sulkowski, Stanisław: 1 article (11/2003)
10.	Kańczuga-Koda, Luiza: 1 article (11/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fibrocystic Breast Disease:

1.	Danazol (Azol)FDA LinkGeneric 12/01/1975 - "Furthermore, Danazol was found to be effective in three patients with chronic cystic mastitis and one patient with fibrocystic disease" 03/01/1982 - "Improved diagnostic procedures and use of a new steroidal agent, danazol (Danocrine), should reduce the need for surgical intervention in fibrocystic breast disease" 07/01/1976 - "Danazol in a dose of 400 mg daily was administrated to 40 patients with chronic cystic mastitis and resulted in a marded improvement in both objective and subjective symptoms in 87.5% of the patients studied" 11/01/1988 - "A prospective randomized double blind trial, using danazol in a dose of 200 mg twice a day, was carried out on 80 women presenting with severe cyclical symptomatic benign mammary dysplasia" 01/01/1984 - "The purpose of the investigation was to study various aspects of danazol treatment in patients with fibrocystic breast disease and pronounced mastodynia" Order ALL the reference details at left...
2.	Progestins (Progestagens)IBA 06/01/1984 - "Progestins, according to Hatcher, also produce these noncontraceptive benefits: protection against PID; decreased dysmenorrhea; decreased menstrual blood loss, decreased iron deficiency anemia; protection against endometrial cancer; protection against fibrocystic breast disease, and fibroadenomas of the breast; decreased bleeding from fibroids; decreased growth of fibroids" 08/01/1982 - "Progestins are effective in managing the increased breast tenderness and aggravation of fibrocystic breast disease that may occur in some estrogen-treated postmenopausal women" 11/30/1975 - "On the basis of the known action of several hormones on the development and functions of the mammary glands, it is concluded that, in addition to an excessive estrogen action or a deficiency of progestins, as is commonly believed, several other hormonal dysfunctions may favor the appearance and development of breast dysplasia and hyperplasia" 08/01/1987 - "While oestrogens may cause cystic lesions and epithelial proliferation in the mammary glands of experimental animals and certain progestogens (chlormadinone acetate and medroxyprogesterone acetate) may induce severe myoepithelial hyperplasia in beagles, the classical oral contraceptives (oestrogens and progestogens) reduce the incidence of fibrocystic breast disease in women" Order ALL the reference details at left...
3.	alpha-TocopherolFDA Link 01/01/1985 - "From this study, d, 1 alpha-tocopherol does not seem to be beneficial in the treatment of patients with mammary dysplasia." 09/01/1981 - "Seventeen young women with clinically confirmed mammary dysplasia and six age-matched controls were treated with alpha-tocopherol" 09/01/1981 - "Endocrine parameters and alpha-tocopherol therapy of patients with mammary dysplasia." 04/01/1981 - "Twenty-six patients with clinically confirmed mammary dysplasia and five age-matched controls were treated with alpha-tocopherol, 600 mg/day" 04/01/1981 - "The results suggest that alpha-tocopherol may serve as an effective agent in treating patients with benign disease, as well as correct the inherent abnormality in serum cholesterol distribution in mammary dysplasia patients." Order ALL the reference details at left...
4.	Estrogens (Estrogen)FDA Link 09/01/1987 - "Safety of estrogen therapy for women with fibrocystic breast disease." 10/01/1974 - "Mammary dysplasia in monkeys caused by estrogens]" 05/01/1999 - "The human breast epithelial cell line, MCF-10A, derived from tissue from a woman undergoing a cutaneous mastectomy for fibrocystic breast disease, is negative for estrogen receptor expression, has undergone minimal genetic changes, retains many of the characteristics of normal breast epithelium and fails to exhibit growth in nude mice" 02/01/1985 - "Use of estrogen replacement therapy was positively associated with fibrocystic breast disease; the odds of disease increased with duration of use, reaching an approximately fivefold excess odds for those who had taken menopausal estrogens for 10 or more years" 01/01/1990 - "Further studies are needed to answer the main question: whether estrogen patterns could represent additive parameters to further categorize breast cystic disease (BCD) or whether they are of minor interest to determine patients' risk of developing breast cancer." Order ALL the reference details at left...
5.	LisurideIBA 12/01/1991 - "To study the efficacy of lisuride in fibrocystic mastopathy, we conducted a clinical trial in 23 out patients, aged 19-50 years, randomly recruited from the gynecological service of the ISSSTE, Dr. Darío Fernández Fierro" 12/01/1991 - "Treatment of fibrocystic breast disease with lisuride]" Order ALL the reference details at left...
6.	ovexIBA 04/01/1981 - "The incidences of cystic-type mammary dysplasia in TP rats, TP rats with E, TP rats with OVEX and E and TP rats with P were 65.5, 86.7, 91.3 and 0%, respectively." 04/01/1981 - "In TP rats with OVEX, a high incidence of mammary dysplasia was found in those given E (95.7%) but not in those given P (0%)" 04/01/1981 - "Ovariectomy (OVEX) of TP rats induced a significant and marked decrease in the incidence of mammary dysplasia (3.7%)" Order ALL the reference details at left...
7.	ProlactinIBA 12/01/1979 - "The sole case of male breast dysplasia analysed in this study did not respond to either human, ovine or bovine prolactin" 01/01/1979 - "63 patients with regular ovulatory cycles, and with fibro-cystic breast disease were selected for observation to study luteal deficiency and prolactin role in the etiology of the disease" 10/01/1992 - "Serum prolactin (PRL) concentrations at baseline and after TRH stimulation were determined in 15 healthy women and in 51 premenopausal patients suffering from Gross Cystic Breast Disease" 10/01/1992 - "Serum prolactin levels in women with gross cystic breast disease." 07/01/1991 - "Different immunoreactivity between cyst fluid and serum prolactin in women with cystic breast disease." Order ALL the reference details at left...
8.	CoffeeIBA 05/01/1986 - "On the basis of the results of the present and previous randomized controlled studies, it thus appears possible to exclude that abstention from coffee and other MTX-containing beverages can substantially reduce signs and symptoms of fibrocystic breast disease within a few months." 02/01/1998 - "On the basis of clinical observations that some women with fibrocystic breast disease experienced resolution of the disease on eliminating methylxanthines from their diet, it has been suggested that coffee intake might be related to breast carcinogenesis" 01/01/1990 - "Reliability was fair to good for less serious or less well-defined medical conditions/procedures, such as cystic breast disease, and for current habits, such as daily coffee consumption" 11/01/1980 - "Coffee and fibrocystic breast disease." 09/01/1985 - "The hypothesis has been raised that coffee consumption may increase the incidence of breast cancer, based on the report that fibrocystic breast disease, a risk factor for breast cancer, regresses after abstention from coffee and other methylxanthines" Order ALL the reference details at left...
9.	Caffeine (No Doz)FDA LinkGeneric 09/01/1986 - "Nonassociation of caffeine and fibrocystic breast disease." 09/01/1984 - "Prospective study of "fibrocystic breast disease" and caffeine consumption." 05/01/1984 - "In a hospital-based case-control study that included 634 women with fibrocystic breast disease and 1,066 comparison women in Connecticut, the occurrence of fibrocystic breast disease was positively associated with average daily consumption of caffeine" 05/01/1984 - "Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study." 06/01/1981 - "Measuring the effect of caffeine restriction on fibrocystic breast disease: the role of graphic stress telethermometry as an objective monitor of disease." Order ALL the reference details at left...
10.	ProgesteroneFDA LinkGeneric 03/01/1979 - "Clinical studies with women being treated with either MPA or progesterone have shown no evidence of treatment-related mammary dysplasia" 08/01/1996 - "Measuring the level of progesterone in 80 women who according to the ultrasound images had fibrocystic mastopathy" 08/01/1996 - "Comparison of ultrasonographic results of the breast with progesterone levels in women with fibrocystic mastopathy]" 05/01/2000 - "Effect of natural "micronized" progesterone on the chorionic gonadotropin concentrations in cyst fluids of women with gross cystic breast disease." 01/01/1986 - "The pathophysiology of fibrocystic breast disease is determined by estrogen predominance and progesterone deficiency that result in hyperproliferation of connective tissue (fibrosis), which is followed by facultative epithelial proliferation; the risk of breast cancer is increased twofold to fourfold in these patients" Order ALL the reference details at left...

Therapies and Procedures

1.	Ovariectomy (Oophorectomy) 04/01/1981 - "Ovariectomy (OVEX) of TP rats induced a significant and marked decrease in the incidence of mammary dysplasia (3.7%)" 12/01/1992 - "t-PA activity in DMBA-mammary carcinoma was decreased markedly by oophorectomy and recovered upon estradiol administration to reach the maximum level at 12 hr. In contrast to its effect on DMBA-mammary carcinoma, estradiol had no effect on t-PA activity in DMBA-mammary dysplasia" Order ALL the reference details at left...
2.	Fat-Restricted Diet (Diet, Fat Restricted) 09/01/1988 - "Two groups of women, postmenopausal women treated for breast cancer and premenopausal women with cystic breast disease accompanied by cyclical mastaligia, participated in an intervention program to determine the feasibility of such a low-fat diet" 09/01/1987 - "Effect of a low-fat diet on hormone levels in women with cystic breast disease." 04/01/1987 - "Effect of a low-fat diet on hormone levels in women with cystic breast disease" 04/01/1987 - "Effect of a low-fat diet on hormone levels in women with cystic breast disease" 04/01/1987 - "It is concluded that the bioactivity of prolactin may be elevated in the serum of patients with cystic breast disease and cyclic mastalgia, without corresponding increases in levels determined by radioimmunoassay; that this abnormality is reversible by a reduction in dietary fat consumption to 20% of the total kilocalories; and that serum prolactin may provide a valuable biomarker in clinical trials of a low-fat diet in women at high breast cancer risk." Order ALL the reference details at left...
3.	Lasers (Laser) 01/01/1983 - "Use of laser flow cytometry in the study of fibrocystic mastopathy and breast cancer]" Order ALL the reference details at left...
4.	Drug Therapy (Chemotherapy) 11/01/2003 - "The purpose of the study was to evaluate the expression and localisation of Cx43 in 40 cases of mammary dysplasia and 29 cases of breast cancer (without primary chemotherapy)" Order ALL the reference details at left...
5.	Estrogen Replacement Therapy 09/01/1987 - "These results suggest an etiologic role of estrogen replacement therapy in the development or promotion of fibrocystic breast disease." 09/01/1987 - "In a hospital-based case-control study conducted in New Haven, Connecticut, women experiencing estrogen replacement therapy were found to be at twice the risk of nonusers for histologically confirmed fibrocystic breast disease (odds ratio = 2; 95 percent confidence limits = 1-3.9) if their menopause was natural" 09/01/1987 - "Estrogen replacement therapy and fibrocystic breast disease." 11/01/1986 - "The association between replacement estrogen use and subsequent development of fibrocystic breast disease was studied at Group Health Cooperative of Puget Sound" 02/01/1985 - "There was no evidence that the positive association between estrogen replacement therapy and the occurrence of fibrocystic breast disease could be explained by differential medical care utilization or other possible risk factors of biopsied fibrocystic breast disease." Order ALL the reference details at left...